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Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…

Methodology · Statistics 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

Neurons in cortical circuits exhibit coordinated spiking activity, and can produce correlated synchronous spikes during behavior and cognition. We recently developed a method for estimating the dynamics of correlated ensemble activity by…

Neurons and Cognition · Quantitative Biology 2013-12-17 Hideaki Shimazaki

Computational modeling is becoming a widely used methodology in modern neuroscience. However, as the complexity of the phenomena under study increases, the analysis of the results emerging from the simulations concomitantly becomes more…

Neurons and Cognition · Quantitative Biology 2020-03-16 Sergio E. Galindo , Pablo Toharia , Oscar D. Robles , Eduardo Ros , Luis Pastor , Jesús A. Garrido

Spiking neural network models characterize the emergent collective dynamics of circuits of biological neurons and help engineer neuro-inspired solutions across fields. Most dynamical systems' models of spiking neural networks typically…

Computational Physics · Physics 2023-04-12 Georg Börner , Fabio Schittler Neves , Marc Timme

Multivariate time-dependent data, where multiple features are observed over time for a set of individuals, are increasingly widespread in many application domains. To model these data we need to account for relations among both time…

Methodology · Statistics 2021-04-08 Alessandro Casa , Charles Bouveyron , Elena Erosheva , Giovanna Menardi

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang

Additive models are flexible regression tools that handle linear as well as nonlinear terms. The latter are typically modelled via smoothing splines. Additive mixed models extend additive models to include random terms when the data are…

Methodology · Statistics 2019-06-10 Marco Geraci

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

Traditional neuron models use analog values for information representation and computation, while all-or-nothing spikes are employed in the spiking ones. With a more brain-like processing paradigm, spiking neurons are more promising for…

Neural and Evolutionary Computing · Computer Science 2021-02-05 Qiang Yu , Shiming Song , Chenxiang Ma , Linqiang Pan , Kay Chen Tan

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

It is often of interest to perform clustering on longitudinal data, yet it is difficult to formulate an intuitive model for which estimation is computationally feasible. We propose a model-based clustering method for clustering objects that…

Methodology · Statistics 2020-05-19 Daniel K. Sewell , Yuguo Chen , William Bernhard , Tracy Sulkin

Objective. Spike sorting, a critical step in neural data processing, aims to classify spiking events from single electrode recordings based on different waveforms. This study aims to develop a novel online spike sorter, NeuSort, using…

Neural and Evolutionary Computing · Computer Science 2023-09-19 Hang Yu , Yu Qi , Gang Pan

The statistical analysis of group studies in neuroscience is particularly challenging due to the complex spatio-temporal nature of the data, its multiple levels and the inter-individual variability in brain responses. In this respect,…

Methodology · Statistics 2025-05-15 Nicolò Margaritella , Vanda Inácio , Ruth King

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines…

Neurons and Cognition · Quantitative Biology 2015-05-13 S. Feldt , J. Waddell , V. L. Hetrick , J. D. Berke , M. Zochowski

Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides…

Machine Learning · Statistics 2017-10-25 Norbert Binkiewicz , Joshua T. Vogelstein , Karl Rohe

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

We introduce a new supervised learning algorithm based to train spiking neural networks for classification. The algorithm overcomes a limitation of existing multi-spike learning methods: it solves the problem of interference between…

Neural and Evolutionary Computing · Computer Science 2021-08-12 Huy Le Nguyen , Dominique Chu

Humans have an exquisite sense of touch which robotic and prosthetic systems aim to recreate. We developed algorithms to create neuron-like (neuromorphic) spiking representations of texture that are invariant to the scanning speed and…

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan
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