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Clustering has long been a popular unsupervised learning approach to identify groups of similar objects and discover patterns from unlabeled data in many applications. Yet, coming up with meaningful interpretations of the estimated clusters…

Methodology · Statistics 2020-05-26 Minjie Wang , Tianyi Yao , Genevera I. Allen

Neural spike trains, which are sequences of very brief jumps in voltage across the cell membrane, were one of the motivating applications for the development of point process methodology. Early work required the assumption of stationarity,…

Applications · Statistics 2011-08-01 Robert E. Kass , Ryan C. Kelly , Wei-Liem Loh

Over the past decades, linear mixed models have attracted considerable attention in various fields of applied statistics. They are popular whenever clustered, hierarchical or longitudinal data are investigated. Nonetheless, statistical…

Methodology · Statistics 2021-09-20 Katarzyna Reluga , María José Lombardía , Stefan Andreas Sperlich

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

With the rising number of interconnected devices and sensors, modeling distributed sensor networks is of increasing interest. Recurrent neural networks (RNN) are considered particularly well suited for modeling sensory and streaming data.…

Machine Learning · Computer Science 2017-11-15 Stephan Baier , Sigurd Spieckermann , Volker Tresp

The activity of ensembles of simultaneously recorded neurons can be represented as a set of points in the space of firing rates. Even though the dimension of this space is equal to the ensemble size, neural activity can be effectively…

Neurons and Cognition · Quantitative Biology 2016-03-17 Luca Mazzucato , Alfredo Fontanini , Giancarlo La Camera

Irregular sampling occurs in many time series modeling applications where it presents a significant challenge to standard deep learning models. This work is motivated by the analysis of physiological time series data in electronic health…

Machine Learning · Computer Science 2021-06-08 Satya Narayan Shukla , Benjamin M. Marlin

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

Neurons and Cognition · Quantitative Biology 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Conventional analysis of neuroscience data involves computing average neural activity over a group of trials and/or a period of time. This approach may be particularly problematic when assessing the response patterns of neurons to more than…

Understanding how stimuli and synaptic connectivity in uence the statistics of spike patterns in neural networks is a central question in computational neuroscience. Maximum Entropy approach has been successfully used to characterize the…

Biological Physics · Physics 2016-11-26 Rodrigo Cofre , Bruno Cessac

This paper presents a constructive algorithm that achieves successful one-shot learning of hidden spike-patterns in a competitive detection task. It has previously been shown (Masquelier et al., 2008) that spike-timing-dependent plasticity…

Neurons and Cognition · Quantitative Biology 2017-08-31 Toby Lightheart , Steven Grainger , Tien-Fu Lu

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

Following the work of arXiv:2101.09512, we are interested in clustering a given multi-variate series in an unsupervised manner. We would like to segment and cluster the series such that the resulting blocks present in each cluster are…

Humans perform remarkably well in many cognitive tasks including pattern recognition. However, the neuronal mechanisms underlying this process are not well understood. Nevertheless, artificial neural networks, inspired in brain circuits,…

Neurons and Cognition · Quantitative Biology 2018-06-28 Gianluca Susi , Luis Anton Toro , Leonides Canuet , Maria Eugenia Lopez , Fernando Maestu , Claudio R. Mirasso , Ernesto Pereda

A variety of real-world processes (over networks) produce sequences of data whose complex temporal dynamics need to be studied. More especially, the event timestamps can carry important information about the underlying network dynamics,…

Machine Learning · Computer Science 2017-03-27 Shuai Xiao , Junchi Yan , Mehrdad Farajtabar , Le Song , Xiaokang Yang , Hongyuan Zha

Growth mixture models are an important tool for detecting group structure in repeated measures data. Unlike traditional clustering methods, they explicitly model the repeat measurements on observations, and the statistical framework they…

Methodology · Statistics 2017-10-20 Abby Flynt , Nema Dean

Until recently obtaining data on populations of networks was typically rare. However, with the advancement of automatic monitoring devices and the growing social and scientific interest in networks, such data has become more widely…

Methodology · Statistics 2020-01-22 Mirko Signorelli , Ernst Wit

In natural scenes, objects generally appear together with other objects. Yet, theoretical studies of neural population coding typically focus on the encoding of single objects in isolation. Experimental studies suggest that neural responses…

Neurons and Cognition · Quantitative Biology 2015-01-05 A. Emin Orhan , Wei Ji Ma

The investigation of input-output systems often requires a sophisticated choice of test inputs to make best use of limited experimental time. Here we present an iterative algorithm that continuously adjusts an ensemble of test inputs…

Biological Physics · Physics 2009-11-07 Christian K. Machens

Neurons can code for multiple variables simultaneously and neuroscientists are often interested in classifying neurons based on their receptive field properties. Statistical models provide powerful tools for determining the factors…

Neurons and Cognition · Quantitative Biology 2022-10-28 Mehrad Sarmashghi , Shantanu P. Jadhav , Uri T. Eden