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Autocatalytic chemical networks play a predominant role in a large number of natural systems such as in metabolic pathways and in ecological networks. Despite recent efforts, the precise impact of thermodynamic constraints on these networks…

Chemical Physics · Physics 2024-06-14 Armand Despons , Yannick de Decker , David Lacoste

We set up a rigorous thermodynamic description of reaction-diffusion systems driven out of equilibrium by time-dependent space-distributed chemostats. Building on the assumption of local equilibrium, nonequilibrium thermodynamic potentials…

Statistical Mechanics · Physics 2018-09-12 Gianmaria Falasco , Riccardo Rao , Massimiliano Esposito

The past twenty years have seen a resurgence of interest in nonequilibrium thermodynamics, thanks to advances in the theory of stochastic processes and in their thermodynamic interpretation. Fluctuation theorems provide fundamental…

Statistical Mechanics · Physics 2017-11-16 Robert Marsland , Jeremy England

In quantum systems, entropy production is typically defined as the quantum relative entropy between two states. This definition provides an upper bound for any flux (of particles, energy, entropy, etc.) of bounded observables, which proves…

Quantum Physics · Physics 2023-11-23 Domingos S. P. Salazar

Fluctuations in biochemical networks, e.g., in a living cell, have a complex origin that precludes a description of such systems in terms of bipartite or multipartite processes, as is usually done in the framework of stochastic and/or…

Statistical Mechanics · Physics 2020-01-29 R. Chétrite , M. L. Rosinberg , T. Sagawa , G. Tarjus

In view of the relation between information and thermodynamics we investigate how much information about an external protocol can be stored in the memory of a stochastic measurement device given an energy budget. We consider a layered…

Quantitative Methods · Quantitative Biology 2015-07-28 Stefano Bo , Marco Del Giudice , Antonio Celani

The productivity of a planetary biosphere is limited by how its free-energy budget is partitioned between maintaining a habitable environment, driving metabolism, and processing heritable information. We derive an upper bound on net primary…

Biological Physics · Physics 2025-12-09 Slava G. Turyshev

We design several examples of constrained, symmetric quantum circuit dynamics that generate non-equilibrium steady states. The qubit networks maintain local memory of the initial conditions and display inhomogeneous subsystem dynamics over…

Quantum Physics · Physics 2025-05-02 Unnati Akhouri , Sarah Shandera , Jackson Henry

Maintained by environmental fluxes, biological systems are thermodynamic processes that operate far from equilibrium without detailed-balance dynamics. Yet, they often exhibit well defined nonequilibrium steady states (NESSs). More…

Statistical Mechanics · Physics 2017-08-02 P. M. Riechers , J. P. Crutchfield

Biological and engineered systems operate by coupling function to the transfer of heat and/or particles down a thermal or chemical gradient. In idealized \textit{deterministically} driven systems, thermodynamic control can be exerted…

Statistical Mechanics · Physics 2016-01-06 Benjamin B. Machta

Living systems operate far from thermal equilibrium by converting the chemical potential of ATP into mechanical work to achieve growth, replication or locomotion. Given time series observations of intra-, inter- or multicellular processes,…

Biological Physics · Physics 2021-11-03 Dominic J. Skinner , Jörn Dunkel

Using information entropy formalism, we consider a one-dimensional system with heat flux and extend the meaning of equilibrium variables to non equilibrium scenarios when classical local equilibrium approach is not applicable; this is…

Statistical Mechanics · Physics 2019-09-10 Sergey Sobolev

When exposed to a thermal gradient, reaction networks can convert thermal energy into the chemical selection of states that would be unfavourable at equilibrium. The kinetics of reaction paths, and thus how fast they dissipate available…

Statistical Mechanics · Physics 2021-09-01 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

We consider a finite-state, continuous-time Markov process, represented in the "linear framework" by a directed graph with labelled edges which specifies the infinitesimal generator of the process. If the graph is strongly connected, the…

Biological Physics · Physics 2023-10-17 Ugur Cetiner , Jeremy Gunawardena

We present a consistent thermodynamic theory for the resonant level model in the wide band limit, whose level energy is driven slowly by an external force. The problem of defining 'system' and 'bath' in the strong coupling regime is…

Mesoscale and Nanoscale Physics · Physics 2017-05-05 Anton Bruch , Mark Thomas , Silvia Viola Kusminskiy , Felix von Oppen , Abraham Nitzan

Genetic regulatory networks enable cells to respond to the changes in internal and external conditions by dynamically coordinating their gene expression profiles. Our ability to make quantitative measurements in these biochemical circuits…

Biological Physics · Physics 2015-03-17 Aleksandra M Walczak , Gašper Tkačik

Thermodynamic principles are often deceptively simple and yet surprisingly powerful. We show how a simple rule, such as the net flow of energy in and out of a moving atom under nonequilibrium steady state condition, can expose the…

Quantum Physics · Physics 2020-11-30 Daniel Reiche , Francesco Intravaia , Jen-Tsung Hsiang , Kurt Busch , Bei-Lok Hu

We show how to construct non-equilibrium thermodynamics for systems too small to be considered thermodynamically in a traditional sense. Through the use of a non-equilibrium ensemble of many replicas of the system which can be viewed as a…

Statistical Mechanics · Physics 2007-05-23 J. M. Rubi , D. Bedeaux , S. Kjelstrup

The analysis of non-equilibrium steady states of biochemical reaction networks relies on finding the configurations of fluxes and chemical potentials satisfying stoichiometric (mass balance) and thermodynamic (energy balance) constraints.…

Molecular Networks · Quantitative Biology 2011-07-13 Daniele De Martino , Matteo Figliuzzi , Andrea De Martino , Enzo Marinari

A positive rate of entropy production at steady state is a distinctive feature of truly non-equilibrium processes. Exact results, while being often limited to simple models, offer a unique opportunity to explore the thermodynamic features…

Statistical Mechanics · Physics 2022-06-29 Henry Alston , Luca Cocconi , Thibault Bertrand
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