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Related papers: Thermodynamic limits on general far-from-equilibri…

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Physical systems driven away from equilibrium by an external controller dissipate heat to the environment; the excess entropy production in the thermal reservoir can be interpreted as a "cost" to transform the system in a finite time. The…

Statistical Mechanics · Physics 2024-12-31 Jérémie Klinger , Grant M. Rotskoff

Central to the functioning of a living cell is its ability to control the readout or expression of information encoded in the genome. In many cases, a single transcription factor protein activates or represses the expression of many genes.…

Molecular Networks · Quantitative Biology 2013-05-29 Aleksandra M. Walczak , Gapser Tkacik , William Bialek

Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…

Molecular Networks · Quantitative Biology 2017-04-12 Thomas E. Ouldridge , Christopher C. Govern , Pieter Rein ten Wolde

Living systems are maintained out-of-equilibrium by external driving forces. At stationarity, they exhibit emergent selection phenomena that break equilibrium symmetries and originate from the expansion of the accessible chemical space due…

Statistical Mechanics · Physics 2026-04-01 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

Empirical complex systems must differentially respond to external perturbations and, at the same time, internally distribute information to coordinate their components. While networked backbones help with the latter, they limit the…

Physics and Society · Physics 2025-04-18 Arsham Ghavasieh , Manlio De Domenico

We find the charge and heat currents caused by a temperature difference applied to a superconducting point contact or to a quantum point contact between a superconducting and normal conductors. The results are formulated in terms of the…

Mesoscale and Nanoscale Physics · Physics 2019-04-24 Sergey S. Pershoguba , Leonid I. Glazman

Living systems maintain or increase local order by working against the Second Law of Thermodynamics. Thermodynamic consistency is restored as they dissipate heat, thereby increasing the net entropy of their environment. Recently introduced…

Biological Physics · Physics 2021-05-03 Dominic J. Skinner , Jörn Dunkel

While ubiquitous, energy redistribution remains a poorly understood facet of the nonequilibrium thermodynamics of biomolecules. At the molecular level, finite-size effects, pronounced nonlinearities, and ballistic processes produce behavior…

Biological Physics · Physics 2019-11-15 Justin E. Elenewski , Kirill A. Velizhanin , Michael Zwolak

Molecular transport maintains cellular structures and functions. For example, lipid and protein diffusion sculpts the dynamic shapes and structures on the cell membrane that perform essential cellular functions, such as cell signaling.…

Soft Condensed Matter · Physics 2024-04-17 Saurav G. Varma , Argha Mitra , Sumantra Sarkar

Nonequilibrium thermodynamics (NET) investigates processes in systems out of global equilibrium. On a mesoscopic level, it provides a statistical dynamic description of various complex phenomena such as chemical reactions, ion transport,…

Statistical Mechanics · Physics 2016-04-20 Hong Qian , Signe Kjelstrup , Anatoly B. Kolomeisky , Dick Bedeaux

Living systems at the molecular scale are composed of many constituents with strong and heterogeneous interactions, operating far from equilibrium, and subject to strong fluctuations. These conditions pose significant challenges to…

Statistical Mechanics · Physics 2023-04-11 Emma Lathouwers , Joseph N. E. Lucero , David A. Sivak

The effect of a thermal environment on electron (or hole) transfer through molecular bridges and on the electron conduction properties of such bridges is studied. Our steady state formalism based on an extension of the Redfield theory (D.…

Condensed Matter · Physics 2009-11-07 Dvira Segal , Abraham Nitzan

We establish a fundamental connection between score-based diffusion models and non-equilibrium thermodynamics by deriving performance limits based on entropy rates. Our main theoretical contribution is a lower bound on the negative…

Machine Learning · Computer Science 2025-10-08 Nathan X. Kodama , Michael Hinczewski

The processing of quantum information is limited by fundamental physical constraints on how information can be encoded, transmitted, and extracted. In particular, the non-orthogonality of quantum states limits their distinguishability, and…

Quantum Physics · Physics 2025-10-17 André T. Cesário , Tiago Debarba

Molecular motors work collectively to transport cargo within cells, with anywhere from one to several hundred motors towing a single cargo. For a broad class of collective-transport systems, we use tools from stochastic thermodynamics to…

Statistical Mechanics · Physics 2022-09-13 Matthew P. Leighton , David A. Sivak

We develop an axiomatic reconstruction of thermodynamics based entirely on two primitive components: a description of what aspects of a system are observed and a reference measure that encodes the underlying descriptive convention. These…

Chemical Physics · Physics 2026-01-21 Tatsuaki Tsuruyama

All current formulations of nonequilibrium thermodynamics of open chemical reaction networks rely on the assumption of non-interacting species. We develop a general theory which accounts for interactions between chemical species within a…

Statistical Mechanics · Physics 2021-03-09 Francesco Avanzini , Emanuele Penocchio , Gianmaria Falasco , Massimiliano Esposito

Equilibrating proteins and other biomacromolecules is cardinal for molecular dynamics simulation of such biological systems in which they perform free dynamics without any externally-applied mechanical constraint, until thermodynamic…

Soft Condensed Matter · Physics 2021-02-11 Ashkan Shekaari , Mahmoud Jafari

We report an experimental and theoretical analysis of the energy exchanged between two conductors kept at different temperature and coupled by the electric thermal noise. Experimentally we determine, as functions of the temperature…

Statistical Mechanics · Physics 2015-06-12 Sergio Ciliberto , Alberto Imparato , Antoine Naert , Marius Tanase

In this paper, we consider the energy cost of communicating using molecular communication. In a simplified scenario, we show that the energy bound in Landauer's principle can be achieved, implying that molecular communication can approach…

Information Theory · Computer Science 2018-05-10 Andrew W. Eckford , Benjamin Kuznets-Speck , Michael Hinczewski , Peter J. Thomas