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Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Artificial Intelligence · Computer Science 2025-09-29 Mbithe Nzomo , Deshendran Moodley

Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…

Electronic health records (EHRs) offer great promises for advancing precision medicine and, at the same time, present significant analytical challenges. Particularly, it is often the case that patient-level data in EHRs cannot be shared…

Methodology · Statistics 2022-07-04 Changgee Chang , Zhiqi Bu , Qi Long

A crucial step within secondary analysis of electronic health records (EHRs) is to identify the patient cohort under investigation. While EHRs contain medical billing codes that aim to represent the conditions and treatments patients may…

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Dataset pruning reduces the storage and training costs of deep learning by selecting an informative subset from a large dataset. However, most existing pruning methods require fully labeled data, which limits their applicability in…

Machine Learning · Computer Science 2026-05-25 Yeseul Cho , Baekrok Shin , Changmin Kang , Chulhee Yun

To date, research on sensor-equipped mobile devices has primarily focused on the purely supervised task of human activity recognition (walking, running, etc), demonstrating limited success in inferring high-level health outcomes from…

Machine Learning · Computer Science 2020-11-10 Dimitris Spathis , Ignacio Perez-Pozuelo , Soren Brage , Nicholas J. Wareham , Cecilia Mascolo

The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potentially unmeasured confounding. In order to improve efficiency, multiple…

Methodology · Statistics 2022-04-19 Baoluo Sun , Zhonghua Liu , Eric Tchetgen Tchetgen

The onset of several silent, chronic diseases such as diabetes can be detected only through diagnostic tests. Due to cost considerations, self-reported outcomes are routinely collected in lieu of expensive diagnostic tests in large-scale…

Applications · Statistics 2015-09-15 Xiangdong Gu , Yunsheng Ma , Raji Balasubramanian

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

A key challenge in building effective regression models for large and diverse populations is accounting for patient heterogeneity. An example of such heterogeneity is in health system risk modeling efforts where different combinations of…

Methodology · Statistics 2022-12-26 Jared D. Huling , Menggang Yu

We introduce BIOMRC, a large-scale cloze-style biomedical MRC dataset. Care was taken to reduce noise, compared to the previous BIOREAD dataset of Pappas et al. (2018). Experiments show that simple heuristics do not perform well on the new…

Computation and Language · Computer Science 2020-05-14 Petros Stavropoulos , Dimitris Pappas , Ion Androutsopoulos , Ryan McDonald

Although increasingly used for research, electronic health records (EHR) often lack gold-standard assessment of key data elements. Linking EHRs to other data sources with higher-quality measurements can improve statistical inference, but…

Methodology · Statistics 2025-03-05 Jenny Shen , Dane Isenberg , Kristin A. Linn , Rebecca A. Hubbard

The extraction of relevant data from Electronic Health Records (EHRs) is crucial to identifying symptoms and automating epidemiological surveillance processes. By harnessing the vast amount of unstructured text in EHRs, we can detect…

Computation and Language · Computer Science 2025-02-10 Juliano Genari , Guilherme Tegoni Goedert

Observational causal inference is useful for decision making in medicine when randomized clinical trials (RCT) are infeasible or non generalizable. However, traditional approaches fail to deliver unconfounded causal conclusions in practice.…

Semi-supervised learning lately has shown much promise in improving deep learning models when labeled data is scarce. Common among recent approaches is the use of consistency training on a large amount of unlabeled data to constrain model…

Machine Learning · Computer Science 2020-11-06 Qizhe Xie , Zihang Dai , Eduard Hovy , Minh-Thang Luong , Quoc V. Le

Wearable devices such as smartwatches are becoming increasingly popular tools for objectively monitoring physical activity in free-living conditions. To date, research has primarily focused on the purely supervised task of human activity…

Signal Processing · Electrical Eng. & Systems 2021-05-26 Dimitris Spathis , Ignacio Perez-Pozuelo , Soren Brage , Nicholas J. Wareham , Cecilia Mascolo

Electronic health records represent a holistic overview of patients' trajectories. Their increasing availability has fueled new hopes to leverage them and develop accurate risk prediction models for a wide range of diseases. Given the…

Electronic health records (EHRs) are increasingly recognized as a cost-effective resource for patient recruitment in clinical research. However, how to optimally select a cohort from millions of individuals to answer a scientific question…

Methodology · Statistics 2023-12-14 Guanghao Zhang , Lauren J. Beesley , Bhramar Mukherjee , Xu Shi

Readily available proxies for time of disease onset such as time of the first diagnostic code can lead to substantial risk prediction error if performing analyses based on poor proxies. Due to the lack of detailed documentation and labor…

Methodology · Statistics 2021-03-09 Stephanie F. Chan , Jue Hou , Xuan Wang , Tianxi Cai
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