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Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Chat models are capable of answering a wide range of questions, however, the accuracy of their responses is highly uncertain. In this research, we propose a specialized PEFT-MedAware model where we utilize parameter-efficient fine-tuning…

Computation and Language · Computer Science 2023-11-20 Keivalya Pandya

The integration of Large Language Models (LLMs) into healthcare promises to transform medical diagnostics, research, and patient care. Yet, the progression of medical LLMs faces obstacles such as complex training requirements, rigorous…

Machine Learning · Computer Science 2024-04-26 Emre Can Acikgoz , Osman Batur İnce , Rayene Bench , Arda Anıl Boz , İlker Kesen , Aykut Erdem , Erkut Erdem

As large language models (LLMs) like OpenAI's GPT series continue to make strides, we witness the emergence of artificial intelligence applications in an ever-expanding range of fields. In medicine, these LLMs hold considerable promise for…

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Recent advances in large language models (LLMs) have enabled general-purpose systems to perform increasingly complex domain-specific reasoning without extensive fine-tuning. In the medical domain, decision-making often requires integrating…

Computation and Language · Computer Science 2025-08-14 Shansong Wang , Mingzhe Hu , Qiang Li , Mojtaba Safari , Xiaofeng Yang

The rapid advancement of large language models(LLMs) has prompted significant interest in their potential applications in medical domains. This paper presents a comprehensive benchmark evaluation of 27 state-of-the-art LLMs on Chinese…

Computation and Language · Computer Science 2025-12-25 Chiung-Yi Tseng , Danyang Zhang , Tianyang Wang , Hongying Luo , Lu Chen , Junming Huang , Jibin Guan , Junfeng Hao , Junhao Song , Xinyuan Song , Ziqian Bi

Large Language Models (LLMs) have brought huge improvements to Artificial Intelligence (AI), which can be applied to general-purpose tasks. However, their application to textual or spoken medical consultations is still an open research…

Artificial Intelligence · Computer Science 2026-05-27 Heriberto Cuayahuitl , Grace Jang

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large Language Models have been tested on medical student-level questions, but their performance in specialized fields like Critical Care Medicine (CCM) is less explored. This study evaluated Meta-Llama 3.1 models (8B and 70B parameters) on…

Computation and Language · Computer Science 2025-09-25 Mahmoud Alwakeel , Aditya Nagori , An-Kwok Ian Wong , Neal Chaisson , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Large Language Models are traditionally finetuned on large instruction datasets. However recent studies suggest that small, high-quality datasets can suffice for general purpose instruction following. This lack of consensus surrounding…

Machine Learning · Computer Science 2023-12-29 Aditi Jha , Sam Havens , Jeremy Dohmann , Alex Trott , Jacob Portes

Large-scale language models (LLMs) like ChatGPT have demonstrated impressive abilities in generating responses based on human instructions. However, their use in the medical field can be challenging due to their lack of specific, in-depth…

Computation and Language · Computer Science 2025-02-25 Yubo Wang , Xueguang Ma , Wenhu Chen

Open-weight versions of large language models (LLMs) are rapidly advancing, with state-of-the-art models like DeepSeek-V3 now performing comparably to proprietary LLMs. This progression raises the question of whether small open-weight LLMs…

Computation and Language · Computer Science 2025-09-24 Damian Stachura , Joanna Konieczna , Artur Nowak

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Leveraging Large Language Models' remarkable proficiency in text-based tasks, recent works on Multi-modal LLMs (MLLMs) extend them to other modalities like vision and audio. However, the progress in these directions has been mostly focused…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sanjoy Chowdhury , Sayan Nag , Subhrajyoti Dasgupta , Jun Chen , Mohamed Elhoseiny , Ruohan Gao , Dinesh Manocha
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