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This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation across various domains, including medicine. We present a comprehensive evaluation of GPT-4, a state-of-the-art LLM, on…

Computation and Language · Computer Science 2023-04-13 Harsha Nori , Nicholas King , Scott Mayer McKinney , Dean Carignan , Eric Horvitz

The development of open-source, multilingual medical language models can benefit a wide, linguistically diverse audience from different regions. To promote this domain, we present contributions from the following: First, we construct a…

Computation and Language · Computer Science 2024-06-04 Pengcheng Qiu , Chaoyi Wu , Xiaoman Zhang , Weixiong Lin , Haicheng Wang , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Language Models (LLMs) have become ubiquitous across various domains, transforming the way we interact with information and conduct research. However, most high-performing LLMs remain confined behind proprietary walls, hindering…

Large Language Models (LLMs) consistently excel in diverse medical Natural Language Processing (NLP) tasks, yet their substantial computational requirements often limit deployment in real-world healthcare settings. In this work, we…

Computation and Language · Computer Science 2026-02-20 Pietro Ferrazzi , Mattia Franzin , Alberto Lavelli , Bernardo Magnini

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

Large Language Models (LLMs) have achieved remarkable performance on a wide range of Natural Language Processing (NLP) benchmarks, often surpassing human-level accuracy. However, their reliability in high-stakes domains such as medicine,…

We are introducing SM70, a 70 billion-parameter Large Language Model that is specifically designed for SpassMed's medical devices under the brand name 'JEE1' (pronounced as G1 and means 'Life'). This large language model provides more…

Computation and Language · Computer Science 2023-12-13 Anubhav Bhatti , Surajsinh Parmar , San Lee

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Large Language Models (LLMs) show potential in medicine, yet clinical adoption is hindered by concerns over factual accuracy, language-specific limitations (e.g., Japanese), and critically, their reliability when required to generate…

Computation and Language · Computer Science 2025-04-28 Wataru Kawakami , Keita Suzuki , Junichiro Iwasawa

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

The rapid advancement of large language models (LLMs) has accelerated their integration into clinical decision support, particularly in prescription review. To enable systematic and fine-grained evaluation, we developed RxBench, a…

Computation and Language · Computer Science 2025-12-03 Yan Yang , Mouxiao Bian , Peiling Li , Bingjian Wen , Ruiyao Chen , Kangkun Mao , Xiaojun Ye , Tianbin Li , Pengcheng Chen , Bing Han , Jie Xu , Kaifeng Qiu , Junyan Wu

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Recent breakthroughs in generative reasoning have fundamentally reshaped how large language models (LLMs) address complex tasks, enabling them to dynamically retrieve, refine, and organize information into coherent multi-step reasoning…

Machine Learning · Computer Science 2026-01-06 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

This paper presents the overview of the development and fine-tuning of large language models (LLMs) designed specifically for answering medical questions. We are mainly improving the accuracy and efficiency of providing reliable answers to…

Computation and Language · Computer Science 2025-01-30 Aysegul Ucar , Soumik Nayak , Anunak Roy , Burak Taşcı , Gülay Taşcı

The recent success of large language models (LLMs) and the scaling law has led to a widespread adoption of larger models. Particularly in the healthcare industry, there is an increasing demand for locally operated LLMs due to security…

Computation and Language · Computer Science 2024-09-23 Issey Sukeda