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Large language models (LLMs) have achieved impressive performance in text summarization, yet their performance often falls short when applied to specialized domains that differ from their original pre-training distribution. While…

Computation and Language · Computer Science 2025-10-10 Xue-Yong Fu , Elena Khasanova , Md Tahmid Rahman Laskar , Harsh Saini , Shashi Bhushan TN

The rise of large language models (LLMs) has created a significant disparity: industrial research labs with their computational resources, expert teams, and advanced infrastructures, can effectively fine-tune LLMs, while individual…

The emergence of Large Language Models (LLMs) presents unprecedented opportunities to revolutionize medical contrastive vision-language pre-training. In this paper, we show how LLMs can facilitate large-scale supervised pre-training,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yingtai Li , Haoran Lai , Xiaoqian Zhou , Shuai Ming , Wenxin Ma , Wei Wei , Shaohua Kevin Zhou

Chemical Language Models (CLMs) pre-trained on large scale molecular data are widely used for molecular property prediction. However, the common belief that increasing training resources such as model size, dataset size, and training…

Machine Learning · Computer Science 2026-05-14 Tatsuya Sagawa , Ryosuke Kojima

Large language models (LLMs) have shown strong ability in generating rich representations across domains such as natural language processing and generation, computer vision, and multimodal learning. However, their application in biomedical…

Genomics · Quantitative Biology 2025-09-30 Luxuan Zhang , Douglas Jiang , Qinglong Wang , Haoqi Sun , Feng Tian

Large pre-trained language models (PLMs) have demonstrated strong performance on natural language understanding (NLU) tasks through fine-tuning. However, fine-tuned models still suffer from overconfident predictions, especially in…

Computation and Language · Computer Science 2023-05-31 Guande He , Jianfei Chen , Jun Zhu

While Large Language Models (LLMs) have exhibited remarkable emergent capabilities through extensive pre-training, they still face critical limitations in generalizing to specialized domains and handling diverse linguistic variations, known…

Computation and Language · Computer Science 2025-05-28 Jinwu Hu , Zhitian Zhang , Guohao Chen , Xutao Wen , Chao Shuai , Wei Luo , Bin Xiao , Yuanqing Li , Mingkui Tan

Text representation plays a critical role in tasks like clustering, retrieval, and other downstream applications. With the emergence of large language models (LLMs), there is increasing interest in harnessing their capabilities for this…

Computation and Language · Computer Science 2025-12-25 Yeqin Zhang , Yizheng Zhao , Chen Hu , Binxing Jiao , Daxin Jiang , Ruihang Miao , Cam-Tu Nguyen

We introduce a new pretraining approach geared for multi-document language modeling, incorporating two key ideas into the masked language modeling self-supervised objective. First, instead of considering documents in isolation, we pretrain…

Computation and Language · Computer Science 2021-09-06 Avi Caciularu , Arman Cohan , Iz Beltagy , Matthew E. Peters , Arie Cattan , Ido Dagan

Large pre-trained models have been vital in recent advancements in domains like language and vision, making model training for individual downstream tasks more efficient and provide superior performance. However, tackling time-series…

Machine Learning · Computer Science 2024-12-06 Harshavardhan Kamarthi , B. Aditya Prakash

Massively multilingual pre-trained language models (MMPLMs) are developed in recent years demonstrating superpowers and the pre-knowledge they acquire for downstream tasks. This work investigates whether MMPLMs can be applied to clinical…

Computation and Language · Computer Science 2023-06-06 Lifeng Han , Gleb Erofeev , Irina Sorokina , Serge Gladkoff , Goran Nenadic

Large Language Models (LLMs) have shown promise in clinical decision support, yet their application to triage remains underexplored. We systematically investigate the capabilities of LLMs in emergency department triage through two key…

Artificial Intelligence · Computer Science 2025-08-06 Joseph Lee , Tianqi Shang , Jae Young Baik , Duy Duong-Tran , Shu Yang , Lingyao Li , Li Shen

The utilization of large language models (LLMs) in the Healthcare domain has generated both excitement and concern due to their ability to effectively respond to freetext queries with certain professional knowledge. This survey outlines the…

Computation and Language · Computer Science 2025-01-28 Kai He , Rui Mao , Qika Lin , Yucheng Ruan , Xiang Lan , Mengling Feng , Erik Cambria

Multilingual Pre-trained Language models (multiPLMs), trained on the Masked Language Modelling (MLM) objective are commonly being used for cross-lingual tasks such as bitext mining. However, the performance of these models is still…

Computation and Language · Computer Science 2025-01-13 Aloka Fernando , Surangika Ranathunga

Pretrained language models (PTLMs) are typically learned over a large, static corpus and further fine-tuned for various downstream tasks. However, when deployed in the real world, a PTLM-based model must deal with data distributions that…

Computation and Language · Computer Science 2022-07-20 Xisen Jin , Dejiao Zhang , Henghui Zhu , Wei Xiao , Shang-Wen Li , Xiaokai Wei , Andrew Arnold , Xiang Ren

Large Language Models (LLMs) have shown remarkable success in supporting a wide range of knowledge-intensive tasks. In specialized domains, there is growing interest in leveraging LLMs to assist subject matter experts with domain-specific…

Computation and Language · Computer Science 2025-12-01 Aman Kumar , Ekant Muljibhai Amin , Xian Yeow Lee , Lasitha Vidyaratne , Ahmed K. Farahat , Dipanjan D. Ghosh , Yuta Koreeda , Chetan Gupta

Multilingual Large Language Models (LLMs) struggle with cross-lingual tasks due to data imbalances between high-resource and low-resource languages, as well as monolingual bias in pre-training. Existing methods, such as bilingual…

Computation and Language · Computer Science 2026-04-14 Weihua Zheng , Chang Liu , Zhengyuan Liu , Xin Huang , Kui Wu , Muhammad Huzaifah Md Shahrin , Aiti Aw , Roy Ka-Wei Lee

A visual-language model (VLM) pre-trained on natural images and text pairs poses a significant barrier when applied to medical contexts due to domain shift. Yet, adapting or fine-tuning these VLMs for medical use presents considerable…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Aisha Urooj Khan , John Garrett , Tyler Bradshaw , Lonie Salkowski , Jiwoong Jason Jeong , Amara Tariq , Imon Banerjee

The increasing use of tools and solutions based on Large Language Models (LLMs) for various tasks in the medical domain has become a prominent trend. Their use in this highly critical and sensitive domain has thus raised important questions…

Computation and Language · Computer Science 2024-01-09 Jean-Baptiste Excoffier , Tom Roehr , Alexei Figueroa , Jens-Michalis Papaioannou , Keno Bressem , Matthieu Ortala

Large Language Models (LLMs), being generic task solvers, are versatile. However, despite the vast amount of data they are trained on, there are speculations about their adaptation capabilities to a new domain. Additionally, the simple…

Computation and Language · Computer Science 2025-09-03 Anum Afzal , Mehul Kumawat , Florian Matthes