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Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

Biological Physics · Physics 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

While cell crawling on a solid surface is relatively well understood, and relies on substrate adhesion, some cells can also swim in the bulk, through mechanisms that are still largely unclear. Here, we propose a minimal model for in-bulk…

Soft Condensed Matter · Physics 2017-12-11 Thomas Le Goff , Benno Liebchen , Davide Marenduzzo

Single and collective cellular oscillations involving the actomyosin cytoskeleton have been observed in numerous biological systems. We show here that a generic model of a contractile material, which is turning over and contracts against an…

Biological Physics · Physics 2014-02-24 Kai Dierkes , Angughali Sumi , Jérôme Solon , Guillaume Salbreux

The emergence of a body axis is a fundamental step in the development of multicellular organisms. In simple systems such as $\textit{Hydra}$, growing evidence suggests that mechanical forces generated by collective cellular activity play a…

Soft Condensed Matter · Physics 2026-01-09 Arthur Hernandez , Cuncheng Zhu , Luca Giomi

Active materials form a class of far-from-equilibrium systems that are driven internally and exhibit self-organization which can be harnessed to perform mechanical work. Inspired by experiments on synthetic active networks we examine limits…

Soft Condensed Matter · Physics 2024-05-02 Shahriar Shadkhoo , Matt Thomson

We have developed several distinct model systems of microtubule-based 3D active isotropic fluids and have compared their dynamical and structural properties. The non-equilibrium dynamics of these fluids is powered by three different types…

Nanoscale molecular transport plays a crucial role in regulating mass diffusion and responsiveness in condensed matter systems. In soft porous crystals, in particular, adsorption of guest molecules induces host framework deformation and…

Soft Condensed Matter · Physics 2026-01-28 Kota Mitsumoto , Kyohei Takae

The interaction of the actin cytoskeleton with cell-substrate adhesions is necessary for cell migration. While the trajectories of motile cells have a stochastic character, investigations of cell motility mechanisms rarely elaborate on the…

Quantitative Methods · Quantitative Biology 2019-03-21 Aydar Uatay

Grasping, in both biological and engineered mechanisms, can be highly sensitive to the gripper and object morphology, as well as perception, and motion planning. Here we circumvent the need for feedback or precise planning by using an array…

Light provides a powerful means of controlling physical behavior of materials but is rarely used to power and guide active matter systems. We demonstrate optical control of liquid crystalline topological solitons dubbed "skyrmions", which…

Soft Condensed Matter · Physics 2020-04-22 Hayley R. O. Sohn , Changda D. Liu , Robert Voinescu , Zezhang Chen , Ivan I. Smalyukh

Chiral active materials are abundant in nature, including the cytoskeleton with attached motor proteins, rotary clusters of bacteria flagella, and self-spinning starfish embryos. These materials break both time reversal and mirror-image…

Soft Condensed Matter · Physics 2025-10-17 Cheng-Tai Lee , Tom C. Lubensky , Tomer Markovich

The motility of adherent eukaryotic cells is driven by the dynamics of the actin cytoskeleton. Despite the common force-generating actin machinery, different cell types often show diverse modes of locomotion that differ in their shape…

Biological Physics · Physics 2022-07-15 T. Moldenhawer , E. Moreno , D. Schindler , S. Flemming , M. Holschneider , W. Huisinga , S. Alonso , C. Beta

In active matter systems, self-propelled particles can self-organize to undergo collective motion, leading to persistent dynamical behavior out of equilibrium. In cells, cytoskeletal filaments and motor proteins self-organize into complex…

Soft Condensed Matter · Physics 2020-05-19 Jeffrey M. Moore , Tyler N. Thompson , Matthew A. Glaser , Meredith D. Betterton

Inspired by recent experiments of cells accumulating on anisotropic substrates, we study a two-dimensional, compressible, isotropic, active fluid in the presence of anisotropic friction. We find that regions of anisotropic friction that are…

Soft Condensed Matter · Physics 2026-03-04 Cody D. Schimming , Brian A. Camley

The sliding friction force exerted by stochastic linkers interacting with a moving filament is calculated. The elastic properties of the substrate on which the linkers are anchored are shown to strongly influence the friction force. In some…

Soft Condensed Matter · Physics 2015-06-17 Pierre Sens

Understanding the out-of-equilibrium properties of noisy microscale systems and the extent to which they can be modulated externally, is a crucial scientific and technological challenge. It holds the promise to unlock disruptive new…

Soft Condensed Matter · Physics 2022-09-21 Stephen Williams , Raphaël Jeanneret , Idan Tuval , Marco Polin

Self-assembly is one of the crucial mechanisms allowing to design multifunctional materials. Soft hybrid materials contain components of different nature and exhibit competitive interactions which drive self-organisation into structures of…

We introduce a simple model of self-propelled agents connected by linear springs, with no explicit alignment rules. Below a critical noise level, the agents self-organize into a collectively translating or rotating group. We derive…

Soft Condensed Matter · Physics 2013-01-15 Eliseo Ferrante , Ali Emre Turgut , Marco Dorigo , Cristián Huepe

Biological systems tightly regulate their physiological state using control signals. This includes the actomyosin cytoskeleton, a contractile active gel that consumes chemical free energy to drive many examples of cellular mechanical…

Soft Condensed Matter · Physics 2025-03-03 James Clarke , Francis Cavanna , Aniket Marne , Anthony Davolio , José Alvarado

How internal forces are transduced into motion through soft, fluid membranes remains a fundamental question in the study of active systems. To investigate this coupling, we develop a minimal system consisting of a single ferromagnetic…

Soft Condensed Matter · Physics 2025-07-11 Paula Magrinya , Arin Escobar Ortiz , Juan L. Aragones , Laura R. Arriaga
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