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Nowadays, a lot of scientific efforts are concentrated on the diagnosis of Alzheimer's Disease (AD) applying deep learning methods to neuroimaging data. Even for 2017, there were published more than a hundred papers dedicated to AD…

Machine Learning · Computer Science 2018-07-31 Yaroslav Shmulev , Mikhail Belyaev

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Learning representations that transfer well to diverse downstream tasks remains a central challenge in representation learning. Existing paradigms -- contrastive learning, self-supervised masking, and denoising auto-encoders -- balance this…

Machine Learning · Computer Science 2025-09-29 Micha Livne

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

We present a new pre-training strategy called M$^{3}$3D ($\underline{M}$ulti-$\underline{M}$odal $\underline{M}$asked $\underline{3D}$) built based on Multi-modal masked autoencoders that can leverage 3D priors and learned cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Muhammad Abdullah Jamal , Omid Mohareri

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that progressively destroys memory and other cognitive domains of the brain. While effective therapeutic management of AD is still in development, it seems reasonable to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-10 Oleg Michailovich , Rinat Mukhometzianov

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Recently,…

Artificial Intelligence · Computer Science 2023-10-06 Kwanseok Oh , Da-Woon Heo , Ahmad Wisnu Mulyadi , Wonsik Jung , Eunsong Kang , Kun Ho Lee , Heung-Il Suk

While deep learning-based Alzheimer's disease (AD) diagnosis has recently made significant advancements, particularly in predicting the conversion of mild cognitive impairment (MCI) to AD based on MRI images, there remains a critical gap in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Donggyu Lee , Juhyeon Park , Taesup Moon

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

Deep learning models for medical image analysis often act as black boxes, seldom aligning with clinical guidelines or explicitly linking decisions to supporting evidence. This is especially critical in Alzheimer's disease (AD), where…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Qiuhui Chen , Xuancheng Yao , Zhenglei Zhou , Xinyue Hu , Yi Hong

Prognostic modeling is essential for forecasting future clinical scores and enabling early detection of Alzheimers disease (AD). While most existing methods focus on predicting the ADAS-Cog global score, they often overlook the predictive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Nur Amirah Abd Hamid , Mohd Ibrahim Shapiai , Daphne Teck Ching Lai

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Vision Transformer has recently gained tremendous popularity in medical image segmentation task due to its superior capability in capturing long-range dependencies. However, transformer requires a large amount of labeled data to be…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Lei Zhu , Jun Zhou , Rick Siow Mong Goh , Yong Liu

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

Learning robust and scalable visual representations from massive multi-view video data remains a challenge in computer vision and autonomous driving. Existing pre-training methods either rely on expensive supervised learning with 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Jialv Zou , Bencheng Liao , Qian Zhang , Wenyu Liu , Xinggang Wang

This paper describes a multi-modal approach for the automatic detection of Alzheimer's disease proposed in the context of the INESC-ID Human Language Technology Laboratory participation in the ADReSS 2020 challenge. Our classification…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-01 Anna Pompili , Thomas Rolland , Alberto Abad

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…

Volumetric neuroimaging examinations like structural Magnetic Resonance Imaging (sMRI) are routinely applied to support the clinical diagnosis of dementia like Alzheimer's Disease (AD). Neuroradiologists examine 3D sMRI to detect and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Meike Nauta , Vincenzo Positano , Christin Seifert