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A fundamental issue in biomedical and environmental sciences is the development of sensitive and robust sensors able to probe the analyte of interest, under physiological and pathological conditions or in environmental samples, and with…

Materials Science · Physics 2015-11-10 Loretta L. del Mercato , Maria Moffa , Rosaria Rinaldi , Dario Pisignano

Fourier ptychographic microscopy (FPM) is a powerful computational imaging modality that achieves high space-bandwidth product imaging for biomedical samples. However, its adoption is limited by slow data acquisition due to the need for…

Optics · Physics 2025-09-09 Shi Zhao , Haowen Zhou , Changhuei Yang

Coating thickness measurement and inspection of defects beneath optically opaque surfaces are among the most promising commercial applications of the terahertz (THz) imaging technology. However, there are two main sources of complexity in…

Applied Physics · Physics 2025-05-14 Arash Karimi , Zachery B. Harris , Erica Heller , Paul Vahey , M. Hassan Arbab

Optoelectronic devices based on graphene and other two-dimensional (2D) materials, such as transition metal dichalcogenides (TMDs) are the focus of wide research interest. The characterization these emerging atomically thin materials and…

Instrumentation and Detectors · Physics 2017-05-09 Adolfo De Sanctis , Gareth F. Jones , Nicola J. Townsend , Monica F. Craciun , Saverio Russo

In multi-photon microscopy (MPM), a recent in-vivo fluorescence microscopy system, the task of image restoration can be decomposed into two interlinked inverse problems: firstly, the characterization of the Point Spread Function (PSF) and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Julien Ajdenbaum , Emilie Chouzenoux , Claire Lefort , Ségolène Martin , Jean-Christophe Pesquet

We propose and examine the use of biphoton pairs, such as those created in parametric down conversion or four-wave mixing, to enhance the precision and the resolution of measuring optical displacements by position-sensitive detection. We…

Quantum Physics · Physics 2016-05-04 Kevin Lyons , Shengshi Pang , Paul G. Kwiat , Andrew N. Jordan

We report the application of machine learning to smartphone based colorimetric detection of pH values. The strip images were used as the training set for Least Squares-Support Vector Machine (LS-SVM) classifier algorithms that were able to…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Ali Y. Mutlu , Volkan Kılıç , Gizem K. Özdemir , Abdullah Bayram , Nesrin Horzum , Mehmet E. Solmaz

Detectors inherently capable of resolving photon numbers have undergone a significant development recently, and this is expected to affect multiplexed periodic single-photon sources where such detectors can find their applications. We…

Quantum Physics · Physics 2020-07-29 Ferenc Bodog , Matyas Mechler , Matyas Koniorczyk , Peter Adam

Optical microscopy contributes to the ever-increasing progress in biological and biomedical studies, as it allows the implementation of minimally invasive experimental pipelines to translate the data of measured samples into valuable…

Quantitative Methods · Quantitative Biology 2025-04-03 Elena Corbetta , Thomas Bocklitz

Surface plasmon resonance (SPR) sensors built on photonic crystal fibers (PCFs) have recently become a promising category of optical sensing platforms. This is primarily due to their high sensitivity, compact structural design and ability…

Physiological sensing deep in tissue, remains a clinical challenge. Here a flexible miniaturised sensing optrode providing a platform to perform minimally invasive in vivo in situ measurements is reported. Silica microspheres covalently…

Conventional optical coherent receivers capture the full electrical field, including amplitude and phase, of a signal waveform by measuring its interference against a stable continuous-wave local oscillator (LO). In optical coherent…

Signal Processing · Electrical Eng. & Systems 2020-06-24 Haoshuo Chen , Nicolas K. Fontaine , Joan M. Gene , Roland Ryf , David T. Neilson , Gregory Raybon

Low concentration hydrogen gas detection is of paramount importance both in space applications as well as medical applications. It is also critically important for safe handling of hydrogen below the explosive limit. Here, we report a novel…

Digital holography (DH) has been widely used for imaging and characterization of micro and nanostructures in materials science and biology and has the potential to provide high-resolution, non-destructive measurements of fluid surfaces as…

Two-photon photopolymerization (TPP) has recently become a popular method for the fabrication of three-dimensional (3D) micro- and nanostructures. The reproduction fidelity of the designed micro- and nanostructures is influenced by…

Optics · Physics 2022-07-12 Yanping He , Qi Shao , Shih-chi Chen , Renjie Zhou

In the work, the new method for the design of the wavelength division multiplexer on the basis of 2D photonic crystal integrated circuit for the ultra-short pulses channel separation is proposed and investigated. The method is based on the…

Inspired by the classic theory, we suggest that the performance of a D-shaped fiber optical surface plasmon resonance (SPR) sensor can be improved by manipulating the fiber core mode. To demonstrate this, we propose a novel fiber SPR sensor…

Applied Physics · Physics 2018-05-16 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

Detecting light is fundamental to all optical experiments and applications. At the single photon level, the quantised nature of light requires specialised detectors, which typically saturate for more than one photon, rendering the…

Any characterization of a single-photon source is not complete without specifying its second-order degree of coherence, i.e., its $g^{(2)}$ function. An accurate measurement of such coherence functions commonly requires high-precision…

Quantum Physics · Physics 2009-09-12 M. Razavi , I. Söllner , E. Bocquillon , C. Couteau , R. Laflamme , G. Weihs

Three-dimensional particle tracking is an essential tool in studying dynamics under the microscope, namely, fluid dynamics in microfluidic devices, bacteria taxis, cellular trafficking. The 3d position can be determined using 2d imaging…

Computer Vision and Pattern Recognition · Computer Science 2015-09-08 Eldad Afik