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This paper studies the best practices for automatic machine learning (AutoML). While previous AutoML efforts have predominantly focused on unimodal data, the multimodal aspect remains under-explored. Our study delves into classification and…

Machine Learning · Computer Science 2024-12-24 Zhiqiang Tang , Zihan Zhong , Tong He , Gerald Friedland

We present $\textbf{MolT5}$ $-$ a self-supervised learning framework for pretraining models on a vast amount of unlabeled natural language text and molecule strings. $\textbf{MolT5}$ allows for new, useful, and challenging analogs of…

Computation and Language · Computer Science 2022-11-07 Carl Edwards , Tuan Lai , Kevin Ros , Garrett Honke , Kyunghyun Cho , Heng Ji

Molecules and materials are the foundation for the development of modern advanced industries such as energy storage systems and semiconductor devices. However, traditional trial-and-error methods or theoretical calculations are highly…

The recent success of large foundation models in artificial intelligence has prompted the emergence of chemical pre-trained models. Despite the growing interest in large molecular pre-trained models that provide informative representations…

Machine Learning · Computer Science 2025-05-26 Jinho Chang , Jong Chul Ye

Recent technological advancements in multimodal machine learning--including the rise of large language models (LLMs)--have improved our ability to collect, process, and analyze diverse multimodal data such as speech, video, and eye gaze in…

With the significant advancements of Large Language Models (LLMs) in the field of Natural Language Processing (NLP), the development of image-text multimodal models has garnered widespread attention. Current surveys on image-text multimodal…

Computation and Language · Computer Science 2024-06-21 Ruifeng Guo , Jingxuan Wei , Linzhuang Sun , Bihui Yu , Guiyong Chang , Dawei Liu , Sibo Zhang , Zhengbing Yao , Mingjun Xu , Liping Bu

Large Language Models (LLMs) have significantly advanced molecular discovery, but existing multimodal molecular architectures fundamentally rely on autoregressive (AR) backbones. This strict left-to-right inductive bias is sub-optimal for…

Artificial Intelligence · Computer Science 2026-04-08 Seohyeon Shin , HanJun Choi , Jun-Hyung Park , Hong Kook Kim , Mansu Kim

Self-supervised learning has recently gained growing interest in molecular modeling for scientific tasks such as AI-assisted drug discovery. Current studies consider leveraging both 2D and 3D molecular structures for representation…

Machine Learning · Computer Science 2023-10-10 Qiying Yu , Yudi Zhang , Yuyan Ni , Shikun Feng , Yanyan Lan , Hao Zhou , Jingjing Liu

As a prominent direction of Artificial General Intelligence (AGI), Multimodal Large Language Models (MLLMs) have garnered increased attention from both industry and academia. Building upon pre-trained LLMs, this family of models further…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chaoyou Fu , Yi-Fan Zhang , Shukang Yin , Bo Li , Xinyu Fang , Sirui Zhao , Haodong Duan , Xing Sun , Ziwei Liu , Liang Wang , Caifeng Shan , Ran He

The integration of molecular and natural language representations has emerged as a focal point in molecular science, with recent advancements in Language Models (LMs) demonstrating significant potential for comprehensive modeling of both…

Biomolecules · Quantitative Biology 2025-03-19 Qizhi Pei , Rui Yan , Kaiyuan Gao , Jinhua Zhu , Lijun Wu

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

Multimodal Large Language Models (MLLMs) are gaining increasing popularity in both academia and industry due to their remarkable performance in various applications such as visual question answering, visual perception, understanding, and…

Computation and Language · Computer Science 2024-09-09 Jian Li , Weiheng Lu , Hao Fei , Meng Luo , Ming Dai , Min Xia , Yizhang Jin , Zhenye Gan , Ding Qi , Chaoyou Fu , Ying Tai , Wankou Yang , Yabiao Wang , Chengjie Wang

Multimodal Large Models (MLMs) are becoming a significant research focus, combining powerful large language models with multimodal learning to perform complex tasks across different data modalities. This review explores the latest…

Machine Learning · Computer Science 2024-07-02 Xinji Mai , Zeng Tao , Junxiong Lin , Haoran Wang , Yang Chang , Yanlan Kang , Yan Wang , Wenqiang Zhang

Molecules play a crucial role in biomedical research and discovery, particularly in the field of small molecule drug development. Given the rapid advancements in large language models, especially the recent emergence of reasoning models, it…

Artificial Intelligence · Computer Science 2025-12-12 Chenyang Zuo , Siqi Fan , Zaiqing Nie

The rapid progress of Multimodal Large Language Models(MLLMs) has transformed the AI landscape. These models combine pre-trained LLMs with various modality encoders. This integration requires a systematic understanding of how different…

Computation and Language · Computer Science 2025-06-06 Jisu An , Junseok Lee , Jeoungeun Lee , Yongseok Son

Deep learning has been the subject of growing interest in recent years. Specifically, a specific type called Multimodal learning has shown great promise for solving a wide range of problems in domains such as language, vision, audio, etc.…

Machine Learning · Computer Science 2022-11-30 Sushil Thapa

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen

Multimodal deep learning systems which employ multiple modalities like text, image, audio, video, etc., are showing better performance in comparison with individual modalities (i.e., unimodal) systems. Multimodal machine learning involves…

Machine Learning · Computer Science 2022-01-19 Anil Rahate , Rahee Walambe , Sheela Ramanna , Ketan Kotecha

Multimodal models are expected to be a critical component to future advances in artificial intelligence. This field is starting to grow rapidly with a surge of new design elements motivated by the success of foundation models in natural…

Computation and Language · Computer Science 2024-06-11 Sai Munikoti , Ian Stewart , Sameera Horawalavithana , Henry Kvinge , Tegan Emerson , Sandra E Thompson , Karl Pazdernik