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In common real-world robotic operations, action and state spaces can be vast and sometimes unknown, and observations are often relatively sparse. How do we learn the full topology of action and state spaces when given only few and sparse…

Machine Learning · Computer Science 2019-07-16 Lingzhi Zhang , Andong Cao , Rui Li , Jianbo Shi

We describe a 3D percolation-type approach to modeling of the processes of aging and certain other properties of tissues analyzed as systems consisting of interacting cells. Lattice sites are designated as regular (healthy) cells, senescent…

Statistical Mechanics · Physics 2016-07-12 Vyacheslav Gorshkov , Vladimir Privman , Sergiy Libert

Epithelial tissues play a fundamental role in various morphogenetic events during development and early embryogenesis. Although epithelial monolayers are often modeled as two-dimensional (2D) elastic surfaces, they distinguish themselves…

Soft Condensed Matter · Physics 2020-06-15 Benjamin Loewe , Francesco Serafin , Suraj Shankar , Mark J. Bowick , M. Cristina Marchetti

The process of morphogenesis, which can be defined as an evolution of the form of an organism, is one of the most intriguing mysteries in the life sciences. It is clear, that gene expression patterns cannot explain the development of the…

Other Quantitative Biology · Quantitative Biology 2013-07-23 Nadya Morozova , Mikhail Shubin

The article presents a new approach to euclidean plane geometry based on projective geometric algebra (PGA). It is designed for anyone with an interest in plane geometry, or who wishes to familiarize themselves with PGA. After a brief…

General Mathematics · Mathematics 2016-11-01 Charles G. Gunn

We study the expressive power of kernel methods and the algorithmic feasibility of multiple kernel learning for a special rich class of kernels. Specifically, we define \emph{Euclidean kernels}, a diverse class that includes most, if not…

Machine Learning · Computer Science 2019-02-14 Pravesh K. Kothari , Roi Livni

In this paper, we analyse a model for the growth of three-dimensional walled cells. In this model the biomechanical expansion of the cell is coupled with the geometry of its wall. We consider that the density of building material depends on…

Analysis of PDEs · Mathematics 2015-02-20 Vincent Calvez , Laetitia Giraldi

It was recently observed by de Vienne et al. that a simple square root transformation of distances between taxa on a phylogenetic tree allowed for an embedding of the taxa into Euclidean space. While the justification for this was based on…

Populations and Evolution · Quantitative Biology 2016-05-04 Mark Layer , John A. Rhodes

The phase-field method has become in recent years the method of choice for simulating microstructural pattern formation during solidification. One of its main advantages is that time-dependent three-dimensional simulations become feasible.…

Materials Science · Physics 2007-05-23 M. Dejmek , R. Folch , A. Parisi , M. Plapp

Numerical investigation of the interaction of electromagnetic fields with eukaryotic cells requires specifically adapted computer models. Virtual microdosimetry, used to investigate exposure, requires volumetric cell models, which are…

Geometrically frustrated solids with non-Euclidean reference metric are ubiquitous in biology and are becoming increasingly relevant in technological applications. Often they acquire a targeted con- figuration of incompatibility through…

Soft Condensed Matter · Physics 2017-08-02 Giuseppe Zurlo , Lev Truskinovsky

One of the central problems in animal and plant developmental biology is deciphering how chemical and mechanical signals interact within a tissue to produce organs of defined size, shape and function. Cell walls in plants impose a unique…

Precise measurements of the lepton properties provide stringent tests of the Standard Model structure and accurate determinations of its parameters. We overview the present status of a few selected topics: lepton universality, QCD tests and…

High Energy Physics - Phenomenology · Physics 2009-11-07 A. Pich

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…

Cells forming various epithelial tissues have a strikingly universal distribution for the number of their edges. It is generally assumed that this topological feature is predefined by the statistics of individual cell divisions in growing…

The shoot apical meristem (SAM) is a dome-shaped collection of cells at the apex of growing plants from which all above-ground tissue ultimately derives. In Arabidopsis thaliana (thale cress), a small flowering weed of the Brassicaceae…

Optimal embedding in the three-dimensional space of exponentially growing squeezed surfaces, like plants leaves, or 2D colonies of exponentially reproducing cells, is considered in the framework of conformal approach. It is shown that the…

Soft Condensed Matter · Physics 2016-11-01 Sergei Nechaev , Kirill Polovnikov

The shape of large on-lattice Eden clusters grown from a single seed is ruled by the underlying lattice anisotropy. This is reflected on the linear growth with time of the interface width ($w\sim t$), in contrast with the KPZ universality…

Statistical Mechanics · Physics 2011-03-09 L. R. Paiva , S. C. Ferreira

We discuss shape profiles emerging in inhomogeneous growth of squeezed tissues. Two approaches are used simultaneously: i) conformal embedding of two-dimensional domain with hyperbolic metrics into the plane, and ii) a pure energetic…

Soft Condensed Matter · Physics 2015-11-25 Sergei Nechaev , Kirill Polovnikov