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Related papers: Transfer Learning for T-Cell Response Prediction

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Tabular data is prevalent across diverse domains in machine learning. With the rapid progress of deep tabular prediction methods, especially pretrained (foundation) models, there is a growing need to evaluate these methods systematically…

Machine Learning · Computer Science 2025-11-10 Han-Jia Ye , Si-Yang Liu , Hao-Run Cai , Qi-Le Zhou , De-Chuan Zhan

Motivated by the size of cell line drug sensitivity data, researchers have been developing machine learning (ML) models for predicting drug response to advance cancer treatment. As drug sensitivity studies continue generating data, a common…

In this paper, we study transfer learning for high-dimensional factor-augmented sparse linear models, motivated by applications in economics and finance where strongly correlated predictors and latent factor structures pose major challenges…

Methodology · Statistics 2026-03-23 Bo Fu , Dandan Jiang

Using transfer learning to adapt a pre-trained "source model" to a downstream "target task" can dramatically increase performance with seemingly no downside. In this work, we demonstrate that there can exist a downside after all: bias…

Machine Learning · Computer Science 2022-07-07 Hadi Salman , Saachi Jain , Andrew Ilyas , Logan Engstrom , Eric Wong , Aleksander Madry

Domain adaptation is the supervised learning setting in which the training and test data are sampled from different distributions: training data is sampled from a source domain, whilst test data is sampled from a target domain. This paper…

Machine Learning · Statistics 2016-10-21 Wouter M. Kouw , Jesse H. Krijthe , Marco Loog , Laurens J. P. van der Maaten

Brain tumor is one of the leading causes of cancer death. The high-grade brain tumors are easier to recurrent even after standard treatment. Therefore, developing a method to predict brain tumor recurrence location plays an important role…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Tongxue Zhou , Alexandra Noeuveglise , Romain Modzelewski , Fethi Ghazouani , Sébastien Thureau , Maxime Fontanilles , Su Ruan

Thomson scattering (TS) diagnostics provide reliable, minimally perturbative measurements of fundamental plasma parameters, such as electron density ($n_e$) and electron temperature ($T_e$). Deep neural networks can provide accurate…

Transfer learning for deep neural networks is the process of first training a base network on a source dataset, and then transferring the learned features (the network's weights) to a second network to be trained on a target dataset. This…

Machine Learning · Computer Science 2019-01-29 Hassan Ismail Fawaz , Germain Forestier , Jonathan Weber , Lhassane Idoumghar , Pierre-Alain Muller

Transfer learning is a common practice that alleviates the need for extensive data to train neural networks. It is performed by pre-training a model using a source dataset and fine-tuning it for a target task. However, not every source…

Machine Learning · Computer Science 2024-10-01 Jiseok Lee , Brian Kenji Iwana

Building accurate models for rare skin diseases remains challenging due to the lack of sufficient labeled data and the inherently long-tailed distribution of available samples. These issues are further complicated by inconsistencies in how…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Zeynep Özdemir , Hacer Yalim Keles , Ömer Özgür Tanrıöver

The models and weights of prior trained Convolutional Neural Networks (CNN) created to perform automated isotopic classification of time-sequenced gamma-ray spectra, were utilized to provide source domain knowledge as training on new…

Data Analysis, Statistics and Probability · Physics 2020-03-25 Eric T. Moore , Johanna L. Turk , William P. Ford , Nathan J. Hoteling , Lance S. McLean

T-cell receptors can recognize foreign peptides bound to major histocompatibility complex (MHC) class-I proteins, and thus trigger the adaptive immune response. Therefore, identifying peptides that can bind to MHC class-I molecules plays a…

Quantitative Methods · Quantitative Biology 2020-12-09 Ziqi Chen , Martin Renqiang Min , Xia Ning

T cell receptor (TCR) recognition of peptide-MHC (pMHC) complexes is a central component of adaptive immunity, with implications for vaccine design, cancer immunotherapy, and autoimmune disease. While recent advances in machine learning…

Quantitative Methods · Quantitative Biology 2026-03-09 Jiarui Li , Zixiang Yin , Zhengming Ding , Samuel J. Landry , Ramgopal R. Mettu

Surrogate models provide efficient alternatives to computationally demanding real world processes but often require large datasets for effective training. A promising solution to this limitation is the transfer of pre-trained surrogate…

Machine Learning · Computer Science 2025-05-14 Shuaiqun Pan , Diederick Vermetten , Manuel López-Ibáñez , Thomas Bäck , Hao Wang

Self-supervised learning has demonstrated considerable potential in hyperspectral representation, yet its application in cross-domain transfer scenarios remains under-explored. Existing methods, however, still rely on source domain…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jianshu Chao , Tianhua Lv , Qiqiong Ma , Yunfei Qiu , Li Fang , Huifang Shen , Wei Yao

The focus in machine learning has branched beyond training classifiers on a single task to investigating how previously acquired knowledge in a source domain can be leveraged to facilitate learning in a related target domain, known as…

Machine Learning · Computer Science 2018-10-30 Tyler R. Scott , Karl Ridgeway , Michael C. Mozer

Transfer learning is known to perform efficiently in many applications empirically, yet limited literature reports the mechanism behind the scene. This study establishes both formal derivations and heuristic analysis to formulate the theory…

Machine Learning · Computer Science 2023-05-10 Huan-Hsin Tseng , Hsin-Yi Lin , Kuo-Hsuan Hung , Yu Tsao

Whole-Slide Image (WSI) is an important tool for estimating cancer prognosis. Current studies generally follow a conventional cancer-specific paradigm in which each cancer corresponds to a single model. However, this paradigm naturally…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Pei Liu , Luping Ji , Jiaxiang Gou , Xiangxiang Zeng

Understanding how information propagates in real-life complex networks yields a better understanding of dynamic processes such as misinformation or epidemic spreading. The recently introduced branch of machine learning methods for learning…

Social and Information Networks · Computer Science 2023-02-21 Sebastian Mežnar , Nada Lavrač , Blaž Škrlj

Health registers contain rich information about individuals' health histories. Here our interest lies in understanding how individuals' health trajectories evolve in a nationwide longitudinal dataset with coded features, such as clinical…

Machine Learning · Computer Science 2024-12-13 Hans Moen , Vishnu Raj , Andrius Vabalas , Markus Perola , Samuel Kaski , Andrea Ganna , Pekka Marttinen