English
Related papers

Related papers: Transfer Learning for T-Cell Response Prediction

200 papers

Data scarcity, bias, and experimental noise are all frequently encountered problems in the application of deep learning to chemical and material science disciplines. Transfer learning has proven effective in compensating for the lack in…

Chemical Physics · Physics 2021-03-16 Florence H. Vermeire , William H. Green

With the emergence of large-scale pre-trained neural networks, methods to adapt such "foundation" models to data-limited downstream tasks have become a necessity. Fine-tuning, preference optimization, and transfer learning have all been…

Machine Learning · Statistics 2025-07-09 Javan Tahir , Surya Ganguli , Grant M. Rotskoff

Cancer claims millions of lives yearly worldwide. While many therapies have been made available in recent years, by in large cancer remains unsolved. Exploiting computational predictive models to study and treat cancer holds great promise…

Quantitative Methods · Quantitative Biology 2022-11-22 Alexander Partin , Thomas S. Brettin , Yitan Zhu , Oleksandr Narykov , Austin Clyde , Jamie Overbeek , Rick L. Stevens

The impressive performance of deep learning architectures is associated with a massive increase in model complexity. Millions of parameters need to be tuned, with training and inference time scaling accordingly, together with energy…

Machine Learning · Computer Science 2023-11-10 Paolo Didier Alfano , Vito Paolo Pastore , Lorenzo Rosasco , Francesca Odone

Transfer learning where the behavior of extracting transferable knowledge from the source domain(s) and reusing this knowledge to target domain has become a research area of great interest in the field of artificial intelligence.…

Machine Learning · Computer Science 2021-09-29 Junyu Xuan , Jie Lu , Guangquan Zhang

Supervised transfer learning has received considerable attention due to its potential to boost the predictive power of machine learning in scenarios where data are scarce. Generally, a given set of source models and a dataset from a target…

Machine Learning · Statistics 2024-01-23 Shunya Minami , Kenji Fukumizu , Yoshihiro Hayashi , Ryo Yoshida

Modern software systems are built to be used in dynamic environments using configuration capabilities to adapt to changes and external uncertainties. In a self-adaptation context, we are often interested in reasoning about the performance…

Software Engineering · Computer Science 2017-04-24 Pooyan Jamshidi , Miguel Velez , Christian Kästner , Norbert Siegmund , Prasad Kawthekar

We study transfer learning for a linear regression task using several least-squares pretrained models that can be overparameterized. We formulate the target learning task as optimization that minimizes squared errors on the target dataset…

Machine Learning · Computer Science 2026-02-19 Daniel Boharon , Yehuda Dar

Clinical prediction is an essential task in the healthcare industry. However, the recent success of transformers, on which large language models are built, has not been extended to this domain. In this research, we explore the use of…

Computation and Language · Computer Science 2023-05-08 Zekai Chen , Mariann Micsinai Balan , Kevin Brown

Transfer Learning (TL) plays a crucial role when a given dataset has insufficient labeled examples to train an accurate model. In such scenarios, the knowledge accumulated within a model pre-trained on a source dataset can be transferred to…

Computation and Language · Computer Science 2018-01-22 Tushar Semwal , Gaurav Mathur , Promod Yenigalla , Shivashankar B. Nair

Transfer learning methods, and in particular domain adaptation, help exploit labeled data in one domain to improve the performance of a certain task in another domain. However, it is still not clear what factors affect the success of domain…

Computation and Language · Computer Science 2021-06-25 Nicolai Pogrebnyakov , Shohreh Shaghaghian

Transfer learning has emerged as a powerful technique in many application problems, such as computer vision and natural language processing. However, this technique is largely ignored in application to genetic data analysis. In this paper,…

Applications · Statistics 2022-06-22 Jinghang Lin , Shan Zhang , Qing Lu

Predicting student performance under varying data distributions is a challenging task. This study proposes a method to improve prediction accuracy by employing transfer learning techniques on the dataset with varying distributions. Using…

Computers and Society · Computer Science 2024-07-19 Yan Zhao

Transfer learning enhances model performance by utilizing knowledge from related domains, particularly when labeled data is scarce. While existing research addresses transfer learning under various distribution shifts in independent…

Machine Learning · Computer Science 2025-04-30 Liyuan Wang , Jiachen Chen , Kathryn L. Lunetta , Danyang Huang , Huimin Cheng , Debarghya Mukherjee

A long-standing challenge in Reinforcement Learning is enabling agents to learn a model of their environment which can be transferred to solve other problems in a world with the same underlying rules. One reason this is difficult is the…

Machine Learning · Computer Science 2019-05-16 Kai Olav Ellefsen , Jim Torresen

Transfer learning is widely used to adapt large pretrained models to new tasks with only a small amount of new data. However, a challenge persists -- the features from the original task often do not fully cover what is needed for unseen…

Machine Learning · Computer Science 2026-02-10 Xingyu Alice Yang , Jianyu Zhang , Léon Bottou

We study the problem of predicting the future, though only in the probabilistic sense of estimating a future state of a time-varying probability distribution. This is not only an interesting academic problem, but solving this extrapolation…

Machine Learning · Statistics 2014-11-21 Christoph H. Lampert

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

In practical machine learning settings, the data on which a model must make predictions often come from a different distribution than the data it was trained on. Here, we investigate the problem of unsupervised multi-source domain…

Machine Learning · Computer Science 2020-09-17 Dustin Wright , Isabelle Augenstein

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz