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This chapter presents methodological reflections on the necessity and utility of artificial intelligence in generative design. Specifically, the chapter discusses how generative design processes can be augmented by AI to deliver in terms of…

Artificial Intelligence · Computer Science 2023-10-16 Pirouz Nourian , Shervin Azadi , Roy Uijtendaal , Nan Bai

Generative design refers to computational design methods that can automatically conduct design exploration under constraints defined by designers. Among many approaches, topology optimization-based generative designs aim to explore diverse…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Seowoo Jang , Soyoung Yoo , Namwoo Kang

Protein engineering is experiencing a paradigmatic shift through the integration of geometric deep learning into computational design workflows. While traditional strategies, such as rational design and directed evolution, have enabled…

Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

The rise of generative artificial intelligence (AI) has facilitated automated product design but often neglects valuable consumer preference data within companies' internal datasets. Additionally, external sources such as social media and…

General Economics · Economics 2025-05-22 Hui Li , Jian Ni , Fangzhu Yang

Consumer-grade printers are widely available, but their ability to print complex objects is limited. Therefore, new designs need to be discovered that serve the same function, but are printable. A representative such problem is to produce a…

Neural and Evolutionary Computing · Computer Science 2018-04-20 Cem C. Tutum , Supawit Chockchowwat , Etienne Vouga , Risto Miikkulainen

Mechanical design and manufacturing workflows conventionally begin with conceptual design, followed by the creation of a computer-aided design (CAD) model and fabrication through material-extrusion (MEX) printing. This process requires…

Machine Learning · Computer Science 2026-03-20 Ziyue Wang , Yayati Jadhav , Peter Pak , Amir Barati Farimani

3D generative modeling is accelerating as the technology allowing the capture of geometric data is developing. However, the acquired data is often inconsistent, resulting in unregistered meshes or point clouds. Many generative learning…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Thomas Besnier , Sylvain Arguillère , Emery Pierson , Mohamed Daoudi

Generating 3D models lies at the core of computer graphics and has been the focus of decades of research. With the emergence of advanced neural representations and generative models, the field of 3D content generation is developing rapidly,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Xiaoyu Li , Qi Zhang , Di Kang , Weihao Cheng , Yiming Gao , Jingbo Zhang , Zhihao Liang , Jing Liao , Yan-Pei Cao , Ying Shan

In aerodynamic shape optimization, the convergence and computational cost are greatly affected by the representation capacity and compactness of the design space. Previous research has demonstrated that using a deep generative model to…

Machine Learning · Computer Science 2021-01-11 Wei Chen , Arun Ramamurthy

Generative artificial intelligence has recently progressed from static image and video synthesis to 3D content generation, culminating in the emergence of 4D generation-the task of synthesizing temporally coherent dynamic 3D assets guided…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Qiaowei Miao , Kehan Li , Jinsheng Quan , Zhiyuan Min , Shaojie Ma , Yichao Xu , Yi Yang , Ping Liu , Yawei Luo

While deep generative models (DGMs) have gained popularity, their susceptibility to biases and other inefficiencies that lead to undesirable outcomes remains an issue. With their growing complexity, there is a critical need for early…

Machine Learning · Computer Science 2024-12-18 Vidya Prasad , Anna Vilanova , Nicola Pezzotti

Test Driven Development (TDD) is one of the major practices of Extreme Programming for which incremental testing and refactoring trigger the code development. TDD has limited adoption in the industry, as it requires more code to be…

Software Engineering · Computer Science 2025-01-15 Moritz Mock , Jorge Melegati , Barbara Russo

Deep generative models (DGM) are neural networks with many hidden layers trained to approximate complicated, high-dimensional probability distributions using a large number of samples. When trained successfully, we can use the DGMs to…

Machine Learning · Computer Science 2021-04-13 Lars Ruthotto , Eldad Haber

This paper presents a novel decoder-based approach for generating manufacturable 3D structures optimized for additive manufacturing. We introduce a deep learning framework that decodes latent representations into geometrically valid,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Abhishek Kumar

With the remarkable success of generative models like ChatGPT, Artificial Intelligence Generated Content (AIGC) is undergoing explosive development. Not limited to text and images, generative models can generate industrial time series data,…

Machine Learning · Computer Science 2025-02-18 Lei Ren , Haiteng Wang , Jinwang Li , Yang Tang , Chunhua Yang

Materials discovery is decisive for tackling urgent challenges related to energy, the environment, health care and many others. In chemistry, conventional methodologies for innovation usually rely on expensive and incremental strategies to…

Machine Learning · Computer Science 2020-06-09 Daniel Schwalbe-Koda , Rafael Gómez-Bombarelli

Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zirong Li , Siyuan Mei , Weiwen Wu , Andreas Maier , Lina Gölz , Yan Xia

The idea of using deep-learning-based molecular generation to accelerate discovery of drug candidates has attracted extraordinary attention, and many deep generative models have been developed for automated drug design, termed molecular…

Biomolecules · Quantitative Biology 2024-05-01 Odin Zhang , Haitao Lin , Hui Zhang , Huifeng Zhao , Yufei Huang , Yuansheng Huang , Dejun Jiang , Chang-yu Hsieh , Peichen Pan , Tingjun Hou

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang