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The period from 2019 to the present marks one of the most significant paradigm shifts in information retrieval (IR) and natural language processing (NLP), culminating in the emergence of powerful large language models (LLMs) from 2022…

Information Retrieval · Computer Science 2026-03-17 Zhichao Xu , Fengran Mo , Zhiqi Huang , Crystina Zhang , Puxuan Yu , Bei Wang , Jimmy Lin , Vivek Srikumar

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Although traditional statistical techniques and machine learning methods have contributed significantly to genetics and, in particular, inherited disease diagnosis, they often struggle with complex, high-dimensional data, a challenge now…

Machine Learning · Computer Science 2025-08-29 Anton Changalidis , Yury Barbitoff , Yulia Nasykhova , Andrey Glotov

The proliferation of long-form documents presents a fundamental challenge to information retrieval (IR), as their length, dispersed evidence, and complex structures demand specialized methods beyond standard passage-level techniques. This…

Information Retrieval · Computer Science 2025-10-28 Minghan Li , Miyang Luo , Tianrui Lv , Yishuai Zhang , Siqi Zhao , Ercong Nie , Guodong Zhou

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

Machine Learning · Computer Science 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Generative Retrieval (GR) is an emerging paradigm in information retrieval that leverages generative models to directly map queries to relevant document identifiers (DocIDs) without the need for traditional query processing or document…

Information Retrieval · Computer Science 2024-06-05 Tzu-Lin Kuo , Tzu-Wei Chiu , Tzung-Sheng Lin , Sheng-Yang Wu , Chao-Wei Huang , Yun-Nung Chen

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

The advent of Large Language Models (LLMs) heralds a pivotal shift in online user interactions with information. Traditional Information Retrieval (IR) systems primarily relied on query-document matching, whereas LLMs excel in comprehending…

Information Retrieval · Computer Science 2023-11-22 Samira Ghodratnama , Mehrdad Zakershahrak

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

The research field of Information Retrieval (IR) has evolved significantly, expanding beyond traditional search to meet diverse user information needs. Recently, Large Language Models (LLMs) have demonstrated exceptional capabilities in…

Content-based image retrieval (CBIR) with self-supervised learning (SSL) accelerates clinicians' interpretation of similar images without manual annotations. We develop a CBIR from the contrastive learning SimCLR and incorporate a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Kristin Qi , Jiali Cheng , Daniel Haehn

The purpose of this Paper is to describe our research on different feature extraction and matching techniques in designing a Content Based Image Retrieval (CBIR) system. Due to the enormous increase in image database sizes, as well as its…

Multimedia · Computer Science 2010-02-10 Mr. Kondekar V. H. , Mr. Kolkure V. S. , Prof. Kore S. N

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of…