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Recent advances in text-to-image (T2I) diffusion models have enabled increasingly realistic synthesis of vehicle damage, raising concerns about their reliability in automated insurance workflows. The ability to generate crash-like imagery…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Teerapong Panboonyuen

Hematoxylin and Eosin (H&E) staining is a widely used sample preparation procedure for enhancing the saturation of tissue sections and the contrast between nuclei and cytoplasm in histology images for medical diagnostics. However, various…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Fangda Li , Zhiqiang Hu , Wen Chen , Avinash Kak

Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Due to the domain gap between real-world and synthetic hazy images, current data-driven dehazing algorithms trained on synthetic datasets perform well on synthetic data but struggle to generalize to real-world scenarios. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Shijun Zhou , Xing Xie , Baojie Fan , Jiandong Tian

Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Recently, large-scale text-to-image (T2I) diffusion models have emerged as a powerful tool for image-to-image translation (I2I), allowing open-domain image translation via user-provided text prompts. This paper proposes frequency-controlled…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Xiang Gao , Zhengbo Xu , Junhan Zhao , Jiaying Liu

An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Thomas Lampert , Odyssée Merveille , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Image-to-image translation (I2I), and particularly its subfield of appearance transfer, which seeks to alter the visual appearance between images while maintaining structural coherence, presents formidable challenges. Despite significant…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Yuteng Ye , Guanwen Li , Hang Zhou , Cai Jiale , Junqing Yu , Yawei Luo , Zikai Song , Qilong Xing , Youjia Zhang , Wei Yang

High-resolution spatial transcriptomics (HR-ST) technologies offer unprecedented insights into tissue architecture but lack standardized frameworks for histological annotation. We present ST2HE, a cross-platform generative framework that…

Quantitative Methods · Quantitative Biology 2025-10-16 Zhentao Liu , Arun Das , Wen Meng , Yu-Chiao Chiu , Shou-Jiang Gao , Yufei Huang

Multiplex immunofluorescence (MxIF) is an emerging imaging technique that produces the high sensitivity and specificity of single-cell mapping. With a tenet of 'seeing is believing', MxIF enables iterative staining and imaging extensive…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Shunxing Bao , Yucheng Tang , Ho Hin Lee , Riqiang Gao , Sophie Chiron , Ilwoo Lyu , Lori A. Coburn , Keith T. Wilson , Joseph T. Roland , Bennett A. Landman , Yuankai Huo

Deep generative models have advanced text-to-online handwriting generation (TOHG), which aims to synthesize realistic pen trajectories conditioned on textual input and style references. However, most existing methods still primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Wei Pan , Huiguo He , Hiuyi Cheng , Yilin Shi , Lianwen Jin

Incomplete data are common in real-world tabular applications, where numerical, categorical, and discrete attributes coexist within a single dataset. This heterogeneous structure presents significant challenges for existing diffusion-based…

Machine Learning · Computer Science 2025-11-19 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal

This paper introduces Hierarchical Image Steganography, a novel method that enhances the security and capacity of embedding multiple images into a single container using diffusion models. HIS assigns varying levels of robustness to images…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Youmin Xu , Xuanyu Zhang , Jiwen Yu , Chong Mou , Xiandong Meng , Jian Zhang

Applying diffusion models to image-to-image translation (I2I) has recently received increasing attention due to its practical applications. Previous attempts inject information from the source image into each denoising step for an iterative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Mengfei Xia , Yu Zhou , Ran Yi , Yong-Jin Liu , Wenping Wang

The integrity of the reconstructed human epidermis generated in vitro could be assessed using histological analyses combined with immunohistochemical staining of keratinocyte differentiation markers. Computer-based analysis of scanned…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Dawid Zamojski , Agnieszka Gogler , Dorota Scieglinska , Michal Marczyk

Differences in staining and imaging procedures can cause significant color variations in histopathology images, leading to poor generalization when deploying deep-learning models trained from a different data source. Various color…

Large-scale text-to-image diffusion models have been a revolutionary milestone in the evolution of generative AI and multimodal technology, allowing wonderful image generation with natural-language text prompt. However, the issue of lacking…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Xiang Gao , Jiaying Liu

The large volume and variety of imaging data from high-throughput screening (HTS) in the pharmaceutical industry present an excellent resource for training virtual staining models. However, the potential of models trained under one set of…

Machine Learning · Computer Science 2024-10-01 Samuel Tonks , Cuong Nguyen , Steve Hood , Ryan Musso , Ceridwen Hopely , Steve Titus , Minh Doan , Iain Styles , Alexander Krull

Spatial transcriptomics (ST) bridges gene expression and tissue morphology but faces clinical adoption barriers due to technical complexity and prohibitive costs. While computational methods predict gene expression from H&E-stained…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ziqiao Weng , Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee AD Cooper , Weidong Cai , Bo Zhou
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