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Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

We introduce SLIMP (Skin Lesion Image-Metadata Pre-training) for learning rich representations of skin lesions through a novel nested contrastive learning approach that captures complex relationships between images and metadata. Melanoma…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Dionysis Christopoulos , Sotiris Spanos , Eirini Baltzi , Valsamis Ntouskos , Konstantinos Karantzalos

Histopathology, particularly hematoxylin and eosin (H\&E) staining, plays a critical role in diagnosing and characterizing pathological conditions by highlighting tissue morphology. However, H\&E-stained images inherently lack molecular…

Computational Engineering, Finance, and Science · Computer Science 2025-01-28 Qing Wang , Wen-jie Chen , Bo Li , Jing Su , Guangyu Wang , Qianqian Song

Vision-Language Pre-training (VLP) shows remarkable progress with the assistance of extremely heavy parameters, which challenges deployment in real applications. Knowledge distillation is well recognized as the essential procedure in model…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Huafeng Kuang , Jie Wu , Xiawu Zheng , Ming Li , Xuefeng Xiao , Rui Wang , Min Zheng , Rongrong Ji

Multimodal Large Language Models (MLLMs) have demonstrated remarkable effectiveness in various general-domain scenarios, such as visual question answering and image captioning. Recently, researchers have increasingly focused on empowering…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yan Shu , Chi Liu , Robin Chen , Derek Li , Bryan Dai

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

As the appearance of medical images is influenced by multiple underlying factors, generative models require rich attribute information beyond labels to produce realistic and diverse images. For instance, generating an image of skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peng Huang , Junhu Fu , Bowen Guo , Zeju Li , Yuanyuan Wang , Yi Guo

Statistical Shape Modeling (SSM) effectively analyzes anatomical variations within populations but is limited by the need for manual localization and segmentation, which relies on scarce medical expertise. Recent advances in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Janmesh Ukey , Tushar Kataria , Shireen Y. Elhabian

In vision-language pre-training (VLP), masked image modeling (MIM) has recently been introduced for fine-grained cross-modal alignment. However, in most existing methods, the reconstruction targets for MIM lack high-level semantics, and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Haowei Liu , Yaya Shi , Haiyang Xu , Chunfeng Yuan , Qinghao Ye , Chenliang Li , Ming Yan , Ji Zhang , Fei Huang , Bing Li , Weiming Hu

Image-text matching (ITM) aims to address the fundamental challenge of aligning visual and textual modalities, which inherently differ in their representations, continuous, high-dimensional image features vs. discrete, structured text. We…

Multimedia · Computer Science 2025-07-14 Junyu Chen , Yihua Gao , Mingyong Li

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

This paper explores training medical vision-language models (VLMs) -- where the visual and language inputs are embedded into a common space -- with a particular focus on scenarios where training data is limited, as is often the case in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman

Recent progress in large-scale CLIP-like vision-language models(VLMs) has greatly advanced medical image analysis. However, most existing medical VLMs still rely on coarse image-text contrastive objectives and fail to capture the systematic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Cheng Liang , Chaoyi Wu , Weike Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

3D medical image analysis is pivotal in numerous clinical applications. However, the scarcity of labeled data and limited generalization capabilities hinder the advancement of AI-empowered models. Radiology reports are easily accessible and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xuefeng Ni , Linshan Wu , Jiaxin Zhuang , Qiong Wang , Mingxiang Wu , Varut Vardhanabhuti , Lihai Zhang , Hanyu Gao , Hao Chen

Surgical AI often involves multiple tasks within a single procedure, like phase recognition or assessing the Critical View of Safety in laparoscopic cholecystectomy. Traditional models, built for one task at a time, lack flexibility,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Soham Walimbe , Britty Baby , Vinkle Srivastav , Nicolas Padoy

Vision-language models have become increasingly powerful for tasks that require an understanding of both visual and linguistic elements, bridging the gap between these modalities. In the context of multimodal clinical AI, there is a growing…

Computation and Language · Computer Science 2024-04-30 Masoud Monajatipoor , Zi-Yi Dou , Aichi Chien , Nanyun Peng , Kai-Wei Chang

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

The generation of realistic medical images from text descriptions has significant potential to address data scarcity challenges in healthcare AI while preserving patient privacy. This paper presents a comprehensive study of text-to-image…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Mikhail Chaichuk , Sushant Gautam , Steven Hicks , Elena Tutubalina
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