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Osteosarcoma is the most common primary bone cancer whose standard treatment includes pre-operative chemotherapy followed by resection. Chemotherapy response is used for predicting prognosis and further management of patients. Necrosis is…

Objective: This study explores a semi-supervised learning (SSL), pseudo-labeled strategy using diverse datasets to enhance lung cancer (LCa) survival predictions, analyzing Handcrafted and Deep Radiomic Features (HRF/DRF) from PET/CT scans…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Mohammad R. Salmanpour , Arman Gorji , Amin Mousavi , Ali Fathi Jouzdani , Nima Sanati , Mehdi Maghsudi , Bonnie Leung , Cheryl Ho , Ren Yuan , Arman Rahmim

Understanding the severity of conditions shown in images in medical diagnosis is crucial, serving as a key guide for clinical assessment, treatment, as well as evaluating longitudinal progression. This paper proposes Con- PrO: a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Hong Nguyen , Hoang Nguyen , Melinda Chang , Hieu Pham , Shrikanth Narayanan , Michael Pazzani

Adversarial attacks exploit the vulnerabilities of convolutional neural networks by introducing imperceptible perturbations that lead to misclassifications, exposing weaknesses in feature representations and decision boundaries. This paper…

Machine Learning · Computer Science 2024-12-30 Longwei Wang , Navid Nayyem , Abdullah Rakin

The clinical integration of deep learning models for brain tumor diagnosis in neuro-oncology is severely constrained by limited expert-annotated MRI data and substantial inter-institutional domain shift arising from variations in scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sapna Sachan , Amulya Kumar Mahto , Prashant Wagambar Patil

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

Machine Learning · Statistics 2021-03-04 Paidamoyo Chapfuwa , Serge Assaad , Shuxi Zeng , Michael J. Pencina , Lawrence Carin , Ricardo Henao

Lung cancer is the leading cause of cancer death worldwide. The critical reason for the deaths is delayed diagnosis and poor prognosis. With the accelerated development of deep learning techniques, it has been successfully applied…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yujiao Wu , Jie Ma , Xiaoshui Huang , Sai Ho Ling , Steven Weidong Su

The ability to predict lung and heart based diseases using deep learning techniques is central to many researchers, particularly in the medical field around the world. In this paper, we present a unique outlook of a very familiar problem of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Sairamvinay Vijayaraghavan , David Haddad , Shikun Huang , Seongwoo Choi

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

We trained and evaluated a localization-based deep CNN for breast cancer screening exam classification on over 200,000 exams (over 1,000,000 images). Our model achieves an AUC of 0.919 in predicting malignancy in patients undergoing breast…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Thibault Févry , Jason Phang , Nan Wu , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Moinak Bhattacharya , Angelica P. Kurtz , Fabio M. Iwamoto , Prateek Prasanna , Gagandeep Singh

Breast cancer is the most commonly occurring cancer worldwide. This cancer caused 670,000 deaths globally in 2022, as reported by the WHO. Yet since health officials began routine mammography screening in age groups deemed at risk in the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Mahmudul Hasan

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Regression via classification (RvC) is a common method used for regression problems in deep learning, where the target variable belongs to a set of continuous values. By discretizing the target into a set of non-overlapping classes, it has…

Machine Learning · Computer Science 2022-04-11 Axel Berg , Magnus Oskarsson , Mark O'Connor

Contrastive learning methods enforce label distance relationships in feature space to improve representation capability for regression models. However, these methods highly depend on label information to correctly recover ordinal…

Machine Learning · Computer Science 2025-12-11 Ce Wang , Weihang Dai , Hanru Bai , Xiaomeng Li

Deep reinforcement learning (RL) algorithms suffer severe performance degradation when the interaction data is scarce, which limits their real-world application. Recently, visual representation learning has been shown to be effective and…

Machine Learning · Computer Science 2022-08-17 Yang Yue , Bingyi Kang , Zhongwen Xu , Gao Huang , Shuicheng Yan

Causal inference, or counterfactual prediction, is central to decision making in healthcare, policy and social sciences. To de-bias causal estimators with high-dimensional data in observational studies, recent advances suggest the…

Machine Learning · Statistics 2020-10-20 Shuxi Zeng , Serge Assaad , Chenyang Tao , Shounak Datta , Lawrence Carin , Fan Li

Background. Absorbed radiation dose to the mandible is an important risk factor in the development of mandibular osteoradionecrosis (ORN) in head and neck cancer (HNC) patients treated with radiotherapy (RT). The prediction of mandibular…

Medical Physics · Physics 2022-06-24 Laia Humbert-Vidan , Vinod Patel , Robin Andlauer , Andrew P King , Teresa Guerrero Urbano

Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…

Genomics · Quantitative Biology 2022-07-12 Xing Wu , Qiulian Fang

Survival analysis consists of studying the elapsed time until an event of interest, such as the death or recovery of a patient in medical studies. This work explores the potential of neural networks in survival analysis from clinical and…

Statistics Theory · Mathematics 2021-05-19 Mathilde Sautreuil , Sarah Lemler , Paul-Henry Cournède