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We evaluate a new approach for achieving diffusion MRI data with high spatial resolution, large volume coverage, and fast acquisition speed. A recent method called gSlider-SMS enables whole-brain sub-millimeter diffusion MRI with high…

Image and Video Processing · Electrical Eng. & Systems 2019-08-19 Justin P. Haldar , Qiuyun Fan , Kawin Setsompop

Stimulated Raman scattering is a well-known nonlinear process that can be harnessed to produce optical gain in a wide variety of media. This effect has been used to produce the first silicon-based lasers and high-gain amplifiers.…

Optics · Physics 2008-10-13 D. R. Solli , P. Koonath , B. Jalali

The "Impulsive Stimulated Raman Scattering" (ISRS), is generally performed using ultrashort laser pulses. It shifts the frequency of the laser beam without any change of the wave surfaces and any appearance of extra lines. ISRS works with…

Astrophysics · Physics 2007-05-23 Jacques Moret-Bailly

We investigate the prospects of using two-mode intensity squeezed twin-beams, generated in Rb vapor, to improve the sensitivity of spectroscopic measurements by engaging two-photon Raman transitions. As a proof of principle demonstration,…

Atomic Physics · Physics 2021-04-21 Nikunjkumar Prajapati , Ziqi Niu , Irina Novikova

We present super-resolved coherent anti-Stokes Raman scattering (CARS) microscopy by implementing phase-resolved image scanning microscopy (ISM), achieving up to two-fold resolution increase as compared with a conventional CARS microscope.…

Optics · Physics 2024-11-22 Anna Zhitnitsky , Elad Benjamin , Ora Bitton , Dan Oron

The low efficiency of Raman spectroscopy can be overcome by placing the active molecules in the vicinity of scatterers, typically rough surfaces or nanostructures with various shapes. This surface-enhanced Raman scattering (SERS) leads to…

Magnetic resonance spectroscopy is universally regarded as one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to length scales greater than 10 \mu m.…

The tantalizing promise of quantum computational speedup in solving certain problems has been strongly supported by recent experimental evidence from a high-fidelity 53-qubit superconducting processor1 and Gaussian boson sampling (GBS) with…

The ongoing miniaturization in nanoscience and -technology challenges the sensitivity and selectivity of experimental analysis methods to the ultimate level of single atoms and molecules. A promising new approach, addressed here, focuses on…

Mesoscale and Nanoscale Physics · Physics 2014-03-28 Stefan Müllegger , Stefano Tebi , Amal K. Das , Wolfgang Schöfberger , Felix Faschinger , Reinhold Koch

Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…

Biological Physics · Physics 2016-08-04 Partha Pratim Mondal

In atomic and molecular phase measurements using laser-induced fluorescence detection, optical cycling can enhance the effective photon detection efficiency and hence improve sensitivity. We show that detecting many photons per atom or…

Atomic Physics · Physics 2018-11-21 Zack Lasner , David DeMille

Integration of electron spin resonance (ESR) in a scanning tunneling microscope (STM) has enabled an all-electrical control of atomic and molecular spins on solid surfaces with atomic-scale precision and energy resolution beyond thermal…

Mesoscale and Nanoscale Physics · Physics 2025-09-03 Deung-Jang Choi , Soo-hyon Phark , Andreas J. Heinrich , Nicolás Lorente

The bosonisation technique is used to calculate the resonant Raman spectrum of a quantum wire with two electronic sub-bands occupied. Close to resonance, the cross section at frequencies in the region of the inter sub-band transitions shows…

Strongly Correlated Electrons · Physics 2009-11-07 E. Mariani , M. Sassetti , B. Kramer

Noise manifests ubiquitously in nonlinear spectroscopy, where multiple sources contribute to experimental signals generating interrelated unwanted components, from random point-wise fluctuations to structured baseline signals. Mitigating…

Optical quantum computing, as well as quantum communication and sensing technology based on quantum correlations are in preparation. These require photodiodes for the detection of about 10^16 photons per second with close to perfect quantum…

Quantum Physics · Physics 2026-02-16 Leif Albers , Jan-Malte Michaelsen , Roman Schnabel

Squeezed light has revolutionized quantum metrology by enhancing interferometry for sensitive applications such as the detection of gravitational waves. Squeezed light has also played a pivotal role in quantum information science with…

The ability to achieve submillimter isotropic resolution diffusion MR imaging (dMRI) is critically important to study fine-scale brain structures, particularly in the cortex. One of the major challenges in performing submillimeter dMRI is…

Medical Physics · Physics 2020-12-08 Wei-Tang Chang , Khoi Minh Huynh , Pew-Thian Yap , Weili Lin

Since the invention of digital cameras there has been a concerted drive towards detector arrays with higher spatial resolution. Microscanning is a technique that provides a final higher resolution image by combining multiple images of a…

We propose and demonstrate a novel technique that combines Raman scattering and optical cycling in molecules with diagonal Franck-Condon factors. This resonance Raman optical cycling manipulates molecules to behave like efficient…

Atomic Physics · Physics 2021-08-26 J. C. Shaw , J. C. Schnaubelt , D. J. McCarron

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake