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We develop a mathematical model of the lung that can estimate independently the air flows and pressures in the upper bronchi. It accounts for the lung multi-scale properties and for the air-tissue interactions. The model equations are…

Tissues and Organs · Quantitative Biology 2025-01-27 Riccardo Di Dio , Michaël Brunengo , Benjamin Mauroy

Disease outbreaks, such as those of Severe Acute Respiratory Syndrome in 2003 and the 2009 pandemic A(H1N1) influenza, have highlighted the potential for airborne transmission in indoor environments. Respirable pathogen-carrying droplets…

Physics and Society · Physics 2012-01-10 M. Robinson , N. I. Stilianakis , Y. Drossinos

This study explores the use of deep learning techniques for analyzing lung Computed Tomography (CT) images. Classic deep learning approaches face challenges with varying slice counts and resolutions in CT images, a diversity arising from…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Chih-Chung Hsu , Chia-Ming Lee , Yang Fan Chiang , Yi-Shiuan Chou , Chih-Yu Jiang , Shen-Chieh Tai , Chi-Han Tsai

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

Chronic obstructive pulmonary disease (COPD) is a lung disease which can be quantified using chest computed tomography (CT) scans. Recent studies have shown that COPD can be automatically diagnosed using weakly supervised learning of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Veronika Cheplygina , Isabel Pino Peña , Jesper Holst Pedersen , David A. Lynch , Lauge Sørensen , Marleen de Bruijne

We propose a simple model of spreading of some infection in an originally healthy population which is different from other models existing in the literature. In particular, we use an operator technique which allows us to describe in a…

Populations and Evolution · Quantitative Biology 2020-10-29 F. Bagarello , F. Gargano , F. Roccati

We examine the spread of an infectious disease, such as one that is caused by a respiratory virus, with two distinct modes of transmission. To do this, we consider a susceptible--infected--susceptible (SIS) disease on a hypergraph, which…

Physics and Society · Physics 2026-01-09 Tung D. Nguyen , Mason A. Porter

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

Seasonal variations in the incidence of infectious diseases are a well-established phenomenon, driven by factors such as climate changes, social behaviors, and ecological interactions that influence host susceptibility and transmission…

Populations and Evolution · Quantitative Biology 2024-10-23 Mahmudul Bari Hridoy

Modeling of respiratory motion is important for a more accurate understanding and accounting of its effect on dose to cancers in the thorax and abdomen by radiotherapy. We have developed a model of respiration-induced organ motion in the…

We develop a spatially dependent generalisation to the Wells-Riley model and its extensions applied to COVID-19, that determines the infection risk due to airborne transmission of viruses. We assume that the concentration of infectious…

Quantitative Methods · Quantitative Biology 2021-05-19 Zechariah Lau , Ian M. Griffiths , Aaron English , Katerina Kaouri

The present paper introduces a new model used to study and analyse the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) epidemic-reported-data from Spain. This is a Hidden Markov Model whose hidden layer is a regeneration process…

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

Populations and Evolution · Quantitative Biology 2021-12-21 Rajat Desikan , Pranesh Padmanabhan , Andrzej M. Kierzek , Piet H. van der Graaf

Breathing is one of the most important body functions because it provides it with oxygen, which is vital for energy production. In addition, the removal of carbon dioxide actively regulates the acid-base level, which is essential for the…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Janosch Kunczik , Kerstin Hubbermann , Lucas Mösch , Andreas Follmann , Michael Czaplik , Carina Barbosa Pereira

Probabilistic forecasting of infectious diseases is crucial for public health but relies on labor-intensive manual model curation by expert modeling teams. This bespoke development bottlenecks scalability to granular geographic resolutions…

Artificial Intelligence · Computer Science 2026-05-18 Sarah Martinson , Michael P. Brenner , Martyna Plomecka , Brian P. Williams , Nicholas G. Reich , Zahra Shamsi

Real-world growth processes, such as epidemic growth, are inherently noisy, uncertain and often involve multiple growth phases. The logistic-sigmoid function has been suggested and applied in the domain of modelling such growth processes.…

Neural and Evolutionary Computing · Computer Science 2020-12-10 Oluwasegun A. Somefun , Kayode Akingbade , Folasade Dahunsi