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Traditional depression screening methods, such as the PHQ-9, are particularly challenging for children in pediatric primary care due to practical limitations. AI has the potential to help, but the scarcity of annotated datasets in mental…

Machine Learning · Computer Science 2025-01-30 Mariia Ignashina , Paulina Bondaronek , Dan Santel , John Pestian , Julia Ive

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

Generative Large Language Models (LLMs) have achieved remarkable advancements in various NLP tasks. However, these advances have not been reflected in the translation task, especially those with moderate model sizes (i.e., 7B or 13B…

Computation and Language · Computer Science 2024-02-07 Haoran Xu , Young Jin Kim , Amr Sharaf , Hany Hassan Awadalla

As ChatGPT and GPT-4 spearhead the development of Large Language Models (LLMs), more researchers are investigating their performance across various tasks. But more research needs to be done on the interpretability capabilities of LLMs, that…

Computation and Language · Computer Science 2023-10-27 Dongfang Li , Jindi Yu , Baotian Hu , Zhenran Xu , Min Zhang

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

Large Language Models (LLMs) consistently excel in diverse medical Natural Language Processing (NLP) tasks, yet their substantial computational requirements often limit deployment in real-world healthcare settings. In this work, we…

Computation and Language · Computer Science 2026-02-20 Pietro Ferrazzi , Mattia Franzin , Alberto Lavelli , Bernardo Magnini

In radiology, Artificial Intelligence (AI) has significantly advanced report generation, but automatic evaluation of these AI-produced reports remains challenging. Current metrics, such as Conventional Natural Language Generation (NLG) and…

Computation and Language · Computer Science 2024-02-20 Qingqing Zhu , Xiuying Chen , Qiao Jin , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Xin Gao , Ronald M Summers , Zhiyong Lu

FPGAs are increasingly adopted in datacenter environments for their reconfigurability and energy efficiency. High-Level Synthesis (HLS) tools have eased FPGA programming by raising the abstraction level from RTL to untimed C/C++, yet…

Machine Learning · Computer Science 2025-05-01 Neha Prakriya , Zijian Ding , Yizhou Sun , Jason Cong

Improving performance on complex tasks and enabling interpretable decision making in large language models (LLMs), especially for clinical applications, requires effective reasoning. Yet this remains challenging without supervised…

Computation and Language · Computer Science 2025-05-26 Che Liu , Haozhe Wang , Jiazhen Pan , Zhongwei Wan , Yong Dai , Fangzhen Lin , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains and are moving towards more specialized areas. Recent advanced proprietary models such as GPT-4 and Gemini have achieved significant advancements…

Computation and Language · Computer Science 2024-10-30 Kaiyan Zhang , Sihang Zeng , Ermo Hua , Ning Ding , Zhang-Ren Chen , Zhiyuan Ma , Haoxin Li , Ganqu Cui , Biqing Qi , Xuekai Zhu , Xingtai Lv , Hu Jinfang , Zhiyuan Liu , Bowen Zhou

Large language models (LLMs) have shown substantial progress in natural language understanding and generation, proving valuable especially in the medical field. Despite advancements, challenges persist due to the complexity and diversity…

Computation and Language · Computer Science 2024-10-18 Yusheng Liao , Shuyang Jiang , Zhe Chen , Yanfeng Wang , Yu Wang

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Hacking poses a significant threat to cybersecurity, inflicting billions of dollars in damages annually. To mitigate these risks, ethical hacking, or penetration testing, is employed to identify vulnerabilities in systems and networks.…

Cryptography and Security · Computer Science 2025-02-24 Isamu Isozaki , Manil Shrestha , Rick Console , Edward Kim

The rapid development of large language models (LLMs) has transformed many industries, including healthcare. However, previous medical LLMs have largely focused on leveraging general medical knowledge to provide responses, without…

Computation and Language · Computer Science 2024-12-23 Ruize Shi , Hong Huang , Wei Zhou , Kehan Yin , Kai Zhao , Yun Zhao

Large language models (LLMs) can potentially democratize access to medical knowledge. While many efforts have been made to harness and improve LLMs' medical knowledge and reasoning capacities, the resulting models are either closed-source…

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu