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Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Customized medical prompts enable Large Language Models (LLM) to effectively address medical dialogue summarization. The process of medical reporting is often time-consuming for healthcare professionals. Implementing medical dialogue…

Computation and Language · Computer Science 2024-01-22 Daphne van Zandvoort , Laura Wiersema , Tom Huibers , Sandra van Dulmen , Sjaak Brinkkemper

Large Language Models (LLMs) evaluation is a patchy and inconsistent landscape, and it is becoming clear that the quality of automatic evaluation metrics is not keeping up with the pace of development of generative models. We aim to improve…

Computation and Language · Computer Science 2023-10-24 Andrea Sottana , Bin Liang , Kai Zou , Zheng Yuan

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

Large Language Models (LLMs) like the GPT and LLaMA families have demonstrated exceptional capabilities in capturing and condensing critical contextual information and achieving state-of-the-art performance in the summarization task.…

Computation and Language · Computer Science 2023-11-06 Prakamya Mishra , Zonghai Yao , Shuwei Chen , Beining Wang , Rohan Mittal , Hong Yu

Modern affective computing systems rely heavily on datasets with human-annotated emotion labels, for training and evaluation. However, human annotations are expensive to obtain, sensitive to study design, and difficult to quality control,…

Computation and Language · Computer Science 2024-12-12 Minxue Niu , Yara El-Tawil , Amrit Romana , Emily Mower Provost

Although supervised machine learning is popular for information extraction from clinical notes, creating large annotated datasets requires extensive domain expertise and is time-consuming. Meanwhile, large language models (LLMs) have…

Computation and Language · Computer Science 2024-01-26 Madhumita Sushil , Travis Zack , Divneet Mandair , Zhiwei Zheng , Ahmed Wali , Yan-Ning Yu , Yuwei Quan , Atul J. Butte

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

Computation and Language · Computer Science 2025-11-17 Arsh Gupta , Ajay Narayanan Sridhar , Bonam Mingole , Amulya Yadav

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Patients must possess the knowledge necessary to actively participate in their care. We present NoteAid-Chatbot, a conversational AI that promotes patient understanding via a novel 'learning as conversation' framework, built on a…

Artificial Intelligence · Computer Science 2025-10-28 Won Seok Jang , Hieu Tran , Manav Mistry , SaiKiran Gandluri , Yifan Zhang , Sharmin Sultana , Sunjae Kown , Yuan Zhang , Zonghai Yao , Hong Yu

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

The escalating volume of collected healthcare textual data presents a unique challenge for automated Multi-Label Text Classification (MLTC), which is primarily due to the scarcity of annotated texts for training and their nuanced nature.…

Computation and Language · Computer Science 2025-03-04 Hajar Sakai , Sarah S. Lam

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

Automated generation of scientific protocols executable by robots can significantly accelerate scientific research processes. Large Language Models (LLMs) excel at Scientific Protocol Formulation Tasks (SPFT), but the evaluation of their…

Computation and Language · Computer Science 2025-04-15 Seungjun Yi , Jaeyoung Lim , Juyong Yoon

This study investigates GPT-4's assessment of its performance in healthcare applications. A simple prompting technique was used to prompt the LLM with questions taken from the United States Medical Licensing Examination (USMLE)…

Artificial Intelligence · Computer Science 2024-03-28 Uttam Dhakal , Aniket Kumar Singh , Suman Devkota , Yogesh Sapkota , Bishal Lamichhane , Suprinsa Paudyal , Chandra Dhakal

Given the rapid ascent of large language models (LLMs), we study the question: (How) can large language models help in reviewing of scientific papers or proposals? We first conduct some pilot studies where we find that (i) GPT-4 outperforms…

Computation and Language · Computer Science 2023-06-02 Ryan Liu , Nihar B. Shah
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