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The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning…

An arbitrary Lagrangian--Eulerian (ALE) finite element method for arbitrarily curved and deforming two-dimensional materials and interfaces is presented here. An ALE theory is developed by endowing the surface with a mesh whose in-plane…

Computational Physics · Physics 2020-03-24 Amaresh Sahu , Yannick A. D. Omar , Roger A. Sauer , Kranthi K. Mandadapu

Elastic Riemannian metrics have been used successfully in the past for statistical treatments of functional and curve shape data. However, this usage has suffered from an important restriction: the function boundaries are assumed fixed and…

Methodology · Statistics 2021-05-19 Darshan Bryner , Anuj Srivastava

The echocardiographic measurement of left ventricular ejection fraction (LVEF) is fundamental to the diagnosis and classification of patients with heart failure (HF). In order to quantify LVEF automatically and accurately, this paper…

Lung adenocarcinoma (LUAD) is a morphologically heterogeneous disease, characterized by five primary histological growth patterns. The classification of such patterns is crucial due to their direct relation to prognosis but the high…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , David Snead , Nasir M. Rajpoot , Shan E Ahmed Raza

Functional properties of neurons are strongly coupled with their morphology. Changes in neuronal activity alter morphological characteristics of dendritic spines. First step towards understanding the structure-function relationship is to…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Muhammad Usman Ghani , Ertunc Erdil , Sumeyra Demir Kanik , Ali Ozgur Argunsah , Anna Felicity Hobbiss , Inbal Israely , Devrim Unay , Tolga Tasdizen , Mujdat Cetin

Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with a five-fold increase in stroke risk. Many individuals with AF go undetected. These individuals are often asymptomatic. There are ongoing debates on whether…

Signal Processing · Electrical Eng. & Systems 2020-10-19 Armand Chocron , Roi Efraim , Franck Mandel , Michael Rueschman , Niclas Palmius , Thomas Penzel , Meyer Elbaz , Joachim A. Behar

Joint models for longitudinal and time-to-event data are increasingly used in health research to characterize the association between biomarker trajectories and the risk of clinical events. However, these models usually assume a linear…

Methodology · Statistics 2026-04-21 Denis Rustand , Håvard Rue , Lisa Le Gall , Karen Leffondre

Accurate delineation of acute ischemic stroke lesions in MRI is a key component of stroke diagnosis and management. In recent years, deep learning models have been successfully applied to the automatic segmentation of such lesions. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Vincent Roca , Martin Bretzner , Hilde Henon , Laurent Puy , Grégory Kuchcinski , Renaud Lopes

Femoroacetabular impingement (FAI) cam morphology is routinely assessed using two-dimensional alpha angles which do not provide specific data on cam size characteristics. The purpose of this study is to implement a novel, automated…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Jessica M. Bugeja , Ying Xia , Shekhar S. Chandra , Nicholas J. Murphy , Jillian Eyles , Libby Spiers , Stuart Crozier , David J. Hunter , Jurgen Fripp , Craig Engstrom

Incorporating shape information is essential for the delineation of many organs and anatomical structures in medical images. While previous work has mainly focused on parametric spatial transformations applied on reference template shapes,…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Wang Zihao , Demarcy Thomas , Vandersteen Clair , Gnansia Dan , Raffaelli Charles , Guevara Nicolas , Delingette Hervé

The basic problem of shape complementarity analysis appears fundamental to applications as diverse as mechanical design, assembly automation, robot motion planning, micro- and nano-fabrication, protein-ligand binding, and rational drug…

Computational Geometry · Computer Science 2017-12-05 Morad Behandish , Horea T. Ilies

Recent research reveals that machine learning (ML) models are highly sensitive to minor changes in their training procedure, such as the inclusion or exclusion of a single data point, leading to conflicting predictions on individual data…

Machine Learning · Computer Science 2025-07-15 Falaah Arif Khan , Denys Herasymuk , Nazar Protsiv , Julia Stoyanovich

Understanding how segmentation performance scales with training data is fundamental for developing data-efficient medical AI systems. In this study, we systematically revisit data scaling behavior across 15 anatomical segmentation tasks…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuetan Chu , Zhongyi Han , Gongning Luo , Xin Gao

Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Utsav Ratna Tuladhar , Richard Simon , Doran Mix , Michael Richards

We propose the approximate Laplace approximation (ALA) to evaluate integrated likelihoods, a bottleneck in Bayesian model selection. The Laplace approximation (LA) is a popular tool that speeds up such computation and equips strong model…

Computation · Statistics 2021-10-07 David Rossell , Oriol Abril , Anirban Bhattacharya

In this paper, we investigate the hemodynamics of a left atrium (LA) by proposing a computational model suitable to provide physically meaningful fluid dynamics indications and detailed blood flow characterization. In particular, we…

Fluid Dynamics · Physics 2022-07-08 Alberto Zingaro , Luca Dede' , Filippo Menghini , Alfio Quarteroni

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

When an amorphous solid is deformed homogeneously, the response exhibits heterogeneous plastic instabilities with localized cooperative rearrangement of cluster of particles. The heterogeneous behavior plays an important role in deciding…

Soft Condensed Matter · Physics 2022-01-31 Meenakshi L , Bhaskar Sen Gupta

Objective: To establish an automated pipeline for post-processing of quantitative spin-lattice relaxation time constant in the rotating frame ($T_{1\rho}$) imaging of knee articular cartilage. Design: The proposed post-processing pipeline…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Junru Zhong , Yongcheng Yao , Fan Xiao , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Siyue Li , Chaoxing Huang , Queenie Chan , James F. Griffith , Weitian Chen