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Patients with atrial fibrillation have a 5-7 fold increased risk of having an ischemic stroke. In these cases, the most common site of thrombus localization is inside the left atrial appendage (LAA) and studies have shown a correlation…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Kristine Aavild Juhl , Jakob Slipsager , Ole de Backer , Klaus Kofoed , Oscar Camara , Rasmus Paulsen

Atrial fibrillation (AF) is a cardiovascular disease identified as one of the main risk factors for stroke. The majority of strokes due to AF are caused by clots originating in the left atrial appendage (LAA). LAA occlusion is an effective…

Image and Video Processing · Electrical Eng. & Systems 2022-05-16 Hrvoje Leventić , Marin Benčević , Danilo Babin , Marija Habijan , Irena Galić

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting over 1% of the population. It is usually triggered by irregular electrical impulses that cause the atria to contract irregularly and…

We present an open-source software pipeline to create patient-specific left atrial (LA) models with fibre orientations and a fibrosis map, suitable for electrophysiology simulations. The semi-automatic pipeline takes as input a contrast…

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia worldwide, with 2% of the population affected. It is associated with an increased risk of strokes, heart failure and other heart-related complications. Monitoring at-risk…

Machine Learning · Computer Science 2021-11-24 Sideshwar J B , Sachin Krishan T , Vishal Nagarajan , Shanthakumar S , Vineeth Vijayaraghavan

The deformation of the left atrium (LA), or its biomechanical function, is closely linked to the health of this cardiac chamber. In atrial fibrillation (AF), atrial biomechanics are significantly altered but the underlying cause of this…

Background Atrial fibrillation is often missed by traditional intermittent electrocardiogram monitoring after ischemic stroke due to its paroxysmal and asymptomatic nature. The knowledge of the unique characteristics of the population with…

Neurons and Cognition · Quantitative Biology 2023-05-25 Yiming Chen , Sihui Wang , Dong Xu

Background: Despite the significant advances made in the field of computational fluid dynamics (CFD) to simulate the left atrium (LA) in atrial fibrillation (AF) conditions, the connection between atrial structure, flow dynamics, and blood…

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is commonly used to visualize and quantify left atrial (LA) scars. The position and extent of scars provide important information of the pathophysiology and progression of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Lei Li , Veronika A. Zimmer , Julia A. Schnabel , Xiahai Zhuang

Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial…

Machine Learning · Computer Science 2024-01-19 Tian Xie

Purpose: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is correlated with increased morbidity and mortality. It is associated with atrial fibrosis, which may be assessed non-invasively using late gadolinium-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Guang Yang , Xiahai Zhuang , Habib Khan , Shouvik Haldar , Eva Nyktari , Lei Li , Rick Wage , Xujiong Ye , Greg Slabaugh , Raad Mohiaddin , Tom Wong , Jennifer Keegan , David Firmin

Background: The arrhythmogenic role of atrial complex morphology has not yet been clearly elucidated. We hypothesized that bumpy tissue geometry can induce action potential duration (APD) dispersion and wavebreak in atrial fibrillation…

Tissues and Organs · Quantitative Biology 2018-12-31 Jun-Seop Song , Jaehyeok Kim , Byounghyun Lim , Young-Seon Lee , Minki Hwang , Boyoung Joung , Eun Bo Shim , Hui-Nam Pak

Atrial fibrillation (AF) represents the most prevalent type of cardiac arrhythmia for which treatment may require patients to undergo ablation therapy. In this surgery cardiac tissues are locally scarred on purpose to prevent electrical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler

Background: Despite the recent advances in computational fluid dynamics (CFD) techniques applied to blood flow within the left atrium (LA), the relationship between atrial geometry, flow patterns, and blood stasis within the left atrial…

Atrial fibrillation (AF) is considered the most common human arrhythmia. Around 99\% of thrombi in non-valvular AF are formed in the left atrial appendage (LAA). Studies suggest that abnormal LAA haemodynamics and the subsequently stagnated…

Automatic segmentation of left atrial (LA) scars from late gadolinium enhanced CMR images is a crucial step for atrial fibrillation (AF) recurrence analysis. However, delineating LA scars is tedious and error-prone due to the variation of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Mengjun Wu , Wangbin Ding , Mingjin Yang , Liqin Huang

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Atrial fibrillation (AF) increases the risk of stroke by a factor of four to five and is the most common abnormal heart rhythm. The progression of AF with age, from short self-terminating episodes to persistence, varies between individuals…

Tissues and Organs · Quantitative Biology 2016-10-12 Kishan A. Manani , Kim Christensen , Nicholas S. Peters

Left atrial (LA) and atrial scar segmentation from late gadolinium enhanced magnetic resonance imaging (LGE MRI) is an important task in clinical practice. %, to guide ablation therapy and predict treatment results for atrial fibrillation…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Lei Li , Veronika A. Zimmer , Julia A. Schnabel , Xiahai Zhuang

Left atrium shape has been shown to be an independent predictor of recurrence after atrial fibrillation (AF) ablation. Shape-based representation is imperative to such an estimation process, where correspondence-based representation offers…

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