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The aim of this article is to introduce a new methodology for constructing morphings between shapes that have identical topology. The morphings are obtained by deforming a reference shape, through the resolution of a sequence of linear…

Numerical Analysis · Mathematics 2025-02-04 Abbas Kabalan , Fabien Casenave , Felipe Bordeu , Virginie Ehrlacher , Alexandre Ern

High-resolution full lung CT scans now enable the detailed segmentation of airway trees up to the 6th branching generation. The airway binary masks display very complex tree structures that may encode biological information relevant to…

Atrial fibrillation (AF) is a leading cause of morbidity and mortality. AF prevalence increases with age, which is attributed to pathophysiological changes that aid AF initiation and perpetuation. Current state-of-the-art models are only…

Tissues and Organs · Quantitative Biology 2015-10-05 Julie Eatock , Yen Ting Lin , Eugene T. Y. Chang , Tobias Galla , Richard H. Clayton

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Length of stay (LOS) prediction in acute stroke is critical for improving care planning. Existing machine learning models have shown suboptimal predictive performance, limited generalisability, and have overlooked system-level factors. We…

Machine Learning · Computer Science 2025-06-17 Zhenran Xu

Appropriate antithrombotic therapy for patients with atrial fibrillation (AF) requires assessment of ischemic stroke and bleeding risks. However, risk stratification schemas such as CHA2DS2-VASc and HAS-BLED have modest predictive capacity…

Cardiac MRI late gadolinium enhancement (LGE) enables non-invasive identification of left atrial (LA) scar, whose spatial distribution is strongly associated with atrial fibrillation (AF) severity and recurrence. However, automatic LA scar…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Jing Zhang , Bastien Bergere , Emilie Bollache , Jonas Leite , Mikaël Laredo , Alban Redheuil , Nadjia Kachenoura

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

Left atrial (LA) segmentation from late gadolinium enhanced magnetic resonance imaging (LGE MRI) is a crucial step needed for planning the treatment of atrial fibrillation. However, automatic LA segmentation from LGE MRI is still…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Lei Li , Veronika A. Zimmer , Julia A. Schnabel , Xiahai Zhuang

There is increasing evidence on the importance of brain morphology in predicting and classifying mental disorders. However, the vast majority of current shape approaches rely heavily on vertex-wise analysis that may not successfully capture…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Yuexuan Wu , Suprateek Kundu , Jennifer S. Stevens , Negar Fani , Anuj Srivastava

We present a fully-automated segmentation and quantification of the left atrial (LA) fibrosis and scars combining two cardiac MRIs, one is the target late gadolinium-enhanced (LGE) image, and the other is an anatomical MRI from the same…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Fuping Wu , Lei Li , Guang Yang , Tom Wong , Raad Mohiaddin , David Firmin , Jennifer Keegan , Lingchao Xu , Xiahai Zhuang

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

Left ventricular assist devices (LVADs) are an increasingly common therapy for patients with advanced heart failure. However, implantation of the LVAD increases the risk of stroke, infection, bleeding, and other serious adverse events…

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motor neuron degeneration, with alterations in neural excitability serving as key indicators. Recent advancements in induced pluripotent stem cell…

Signal Processing · Electrical Eng. & Systems 2025-05-27 Nisal Ranasinghe , Dzung Do-Ha , Simon Maksour , Tamasha Malepathirana , Sachith Seneviratne , Lezanne Ooi , Saman Halgamuge

Atrial Fibrillation is a heart condition characterized by erratic heart rhythms caused by chaotic propagation of electrical impulses in the atria, leading to numerous health complications. State-of-the-art models employ complex algorithms…

Quantitative Methods · Quantitative Biology 2019-12-02 Paul Samuel Ignacio , David Uminsky , Christopher Dunstan , Esteban Escobar , Luke Trujillo

Effectively modeling irregularly sampled longitudinal data is essential for understanding disease progression and improving risk prediction. We propose a two-view mixture model that integrates static baseline covariates and longitudinal…

Quantitative Methods · Quantitative Biology 2026-04-03 Shen Jia , David Selby , Mark A Little , Tin Lok James Ng

Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia and is associated with increased morbidity and mortality. The effectiveness of current clinical interventions for AF is often limited by an incomplete understanding…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Lucas Beveridge , Le Zhang

Amyotrophic lateral sclerosis (ALS) is a severe disease with a typical survival of 3-5 years after symptom onset. Current treatments offer only limited life extension, and the variability in patient responses highlights the need for…

Machine Learning · Computer Science 2025-11-05 Guillaume Tejedor , Veronika Peralta , Nicolas Labroche , Patrick Marcel , Hélène Blasco , Hugo Alarcan

Federated Learning (FL) faces major challenges in real-world deployments due to statistical heterogeneity across clients and system heterogeneity arising from resource-constrained devices. While clustering-based approaches mitigate…

Machine Learning · Computer Science 2026-03-03 Om Govind Jha , Harsh Shukla , Haroon R. Lone

BACKGROUND: Atrial fibrillation (AF), the most common arrhythmia, is linked to high morbidity and mortality. In a fast-evolving AF rhythm control treatment era, predicting AF recurrence after its onset may be crucial to achieve the optimal…