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Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

This study investigates the efficacy of Large Language Models (LLMs) in interactive language therapy for high-functioning autistic adolescents. With the rapid advancement of artificial intelligence, particularly in natural language…

Human-Computer Interaction · Computer Science 2023-11-17 Yujin Cho , Mingeon Kim , Seojin Kim , Oyun Kwon , Ryan Donghan Kwon , Yoonha Lee , Dohyun Lim

Large language models (LLMs) are gaining increasing interests to improve clinical efficiency for medical diagnosis, owing to their unprecedented performance in modelling natural language. Ensuring the safe and reliable clinical…

Computation and Language · Computer Science 2024-03-26 Lei Liu , Xiaoyan Yang , Fangzhou Li , Chenfei Chi , Yue Shen , Shiwei Lyu Ming Zhang , Xiaowei Ma , Xiangguo Lyu , Liya Ma , Zhiqiang Zhang , Wei Xue , Yiran Huang , Jinjie Gu

The rise of large language models (LLMs) has revolutionized the way that we interact with artificial intelligence systems through natural language. However, LLMs often misinterpret user queries because of their uncertain intention, leading…

Computation and Language · Computer Science 2024-02-07 Jing-Cheng Pang , Heng-Bo Fan , Pengyuan Wang , Jia-Hao Xiao , Nan Tang , Si-Hang Yang , Chengxing Jia , Sheng-Jun Huang , Yang Yu

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

This study explores integrating large language models (LLMs) with situational awareness-based planning (SAP) to enhance the decision-making capabilities of AI agents in dynamic and uncertain environments. We employ a multi-agent reasoning…

Artificial Intelligence · Computer Science 2024-06-18 Liman Wang , Hanyang Zhong

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Large language models (LLMs) and large multimodal models (LMMs) promise to accelerate biomedical discovery, yet their reliability remains unclear. We introduce ARIEL (AI Research Assistant for Expert-in-the-Loop Learning), an open-source…

Large Language Models (LLMs) are transforming artificial intelligence, enabling autonomous agents to perform diverse tasks across various domains. These agents, proficient in human-like text comprehension and generation, have the potential…

Artificial Intelligence · Computer Science 2024-04-10 Saikat Barua

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

Computation and Language · Computer Science 2026-01-21 Hongyang Ma , Tiantian Gu , Huaiyuan Sun , Huilin Zhu , Yongxin Wang , Jie Li , Wubin Sun , Zeliang Lian , Yinghong Zhou , Yi Gao , Shirui Wang , Zhihui Tang
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