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Related papers: MolBind: Multimodal Alignment of Language, Molecul…

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We present TerraBind, a foundation model for protein-ligand structure and binding affinity prediction that achieves 26-fold faster inference than state-of-the-art methods while improving affinity prediction accuracy by $\sim$20\%. Current…

In this paper, we propose EventBind, a novel and effective framework that unleashes the potential of vision-language models (VLMs) for event-based recognition to compensate for the lack of large-scale event-based datasets. In particular,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Jiazhou Zhou , Xu Zheng , Yuanhuiyi Lyu , Lin Wang

Despite progress in gloss-free Sign Language Translation (SLT), traditional single modality end-to-end approaches consistently fail on two critical components of natural signing: the precise recognition of high-speed fingerspelling and the…

Computation and Language · Computer Science 2025-12-05 Marshall Thomas , Edward Fish , Richard Bowden

We present BioLangFusion, a simple approach for integrating pre-trained DNA, mRNA, and protein language models into unified molecular representations. Motivated by the central dogma of molecular biology (information flow from gene to…

Machine Learning · Computer Science 2025-06-11 Amina Mollaysa , Artem Moskale , Pushpak Pati , Tommaso Mansi , Mangal Prakash , Rui Liao

In this paper, we study how to use masked signal modeling in vision and language (V+L) representation learning. Instead of developing masked language modeling (MLM) and masked image modeling (MIM) independently, we propose to build joint…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Gukyeong Kwon , Zhaowei Cai , Avinash Ravichandran , Erhan Bas , Rahul Bhotika , Stefano Soatto

This paper presents M3L-Contrast -- a novel multimodal multilingual (M3L) neural topic model for comparable data that maps texts from multiple languages and images into a shared topic space. Our model is trained jointly on texts and images…

Computation and Language · Computer Science 2022-11-16 Elaine Zosa , Lidia Pivovarova

The integration of molecular and natural language representations has emerged as a focal point in molecular science, with recent advancements in Language Models (LMs) demonstrating significant potential for comprehensive modeling of both…

Biomolecules · Quantitative Biology 2025-03-19 Qizhi Pei , Rui Yan , Kaiyuan Gao , Jinhua Zhu , Lijun Wu

Most machine learning models for molecular property prediction rely on a single molecular representation (either a sequence, a graph, or a 3D structure) and treat molecular geometry as static. We present MolFM-Lite, a multi-modal model that…

Multimodal learning seeks to combine data from multiple input sources to enhance the performance of different downstream tasks. In real-world scenarios, performance can degrade substantially if some input modalities are missing. Existing…

Machine Learning · Computer Science 2024-10-10 Niki Nezakati , Md Kaykobad Reza , Ameya Patil , Mashhour Solh , M. Salman Asif

We explore Multimodal Large Language Models (MLLMs), which integrate LLMs like GPT-4 to handle multimodal data, including text, images, audio, and more. MLLMs demonstrate capabilities such as generating image captions and answering…

Computation and Language · Computer Science 2025-01-09 Shezheng Song , Xiaopeng Li , Shasha Li , Shan Zhao , Jie Yu , Jun Ma , Xiaoguang Mao , Weimin Zhang

Recently, a noticeable trend has emerged in developing pre-trained foundation models in the domains of CV and NLP. However, for molecular pre-training, there lacks a universal model capable of effectively applying to various categories of…

Biomolecules · Quantitative Biology 2024-05-21 Shikun Feng , Yuyan Ni , Minghao Li , Yanwen Huang , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

A unified representation space in multi-modal learning is essential for effectively integrating diverse data sources, such as text, images, and audio, to enhance efficiency and performance across various downstream tasks. Recent binding…

Machine Learning · Computer Science 2025-10-08 Minoh Jeong , Zae Myung Kim , Min Namgung , Dongyeop Kang , Yao-Yi Chiang , Alfred Hero

Recent advances in image-text pretraining have significantly enhanced visual understanding by aligning visual and textual representations. Contrastive Language-Image Pretraining (CLIP) has played a pivotal role in multimodal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Zihan Li , Yiqing Wang , Sina Farsiu , Paul Kinahan

We propose to solve the natural language inference problem without any supervision from the inference labels via task-agnostic multimodal pretraining. Although recent studies of multimodal self-supervised learning also represent the…

Computation and Language · Computer Science 2020-10-19 Wanyun Cui , Guangyu Zheng , Wei Wang

Large-scale natural image-text datasets, especially those automatically collected from the web, often suffer from loose semantic alignment due to weak supervision, while medical datasets tend to have high cross-modal correlation but low…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shengzhu Yang , Jiawei Du , Shuai Lu , Weihang Zhang , Ningli Wang , Huiqi Li

Multi-modal embeddings form the foundation for vision-language models, such as CLIP embeddings, the most widely used text-image embeddings. However, these embeddings are vulnerable to subtle misalignment of cross-modal features, resulting…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Yilin Ye , Shishi Xiao , Xingchen Zeng , Wei Zeng

Until recently, the number of public real-world text images was insufficient for training scene text recognizers. Therefore, most modern training methods rely on synthetic data and operate in a fully supervised manner. Nevertheless, the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Aviad Aberdam , Roy Ganz , Shai Mazor , Ron Litman

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

Drug target interaction (DTI) prediction is a cornerstone of computational drug discovery, enabling rational design, repurposing, and mechanistic insights. While deep learning has advanced DTI modeling, existing approaches primarily rely on…

Machine Learning · Computer Science 2025-11-05 Feng Jiang , Amina Mollaysa , Hehuan Ma , Tommaso Mansi , Junzhou Huang , Mangal Prakash , Rui Liao

Existing foundation models, such as CLIP, aim to learn a unified embedding space for multimodal data, enabling a wide range of downstream web-based applications like search, recommendation, and content classification. However, these models…

Machine Learning · Computer Science 2025-04-28 Yufei He , Yuan Sui , Xiaoxin He , Yue Liu , Yifei Sun , Bryan Hooi
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