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Data science relies on pipelines that are organized in the form of interdependent computational steps. Each step consists of various candidate algorithms that maybe used for performing a particular function. Each algorithm consists of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-04 Aritra Chowdhury , Malik Magdon-Ismail , Bulent Yener

Artifact Detection (AD) techniques minimize the impact of artifacts on physiologic data acquired in Critical Care Units (CCU) by assessing quality of data prior to Clinical Event Detection (CED) and Parameter Derivation (PD). This…

Signal Processing · Electrical Eng. & Systems 2018-05-02 Shermeen Nizami , James R. Green , Carolyn McGregor

Purpose: Automatic methods are required for the early detection of hepatic steatosis to avoid progression to cirrhosis and cancer. Here, we developed a fully automated deep learning pipeline to quantify hepatic steatosis on non-contrast…

Quantitative Methods · Quantitative Biology 2022-02-08 Zhongyi Zhang , Jakob Weiss , Jana Taron , Roman Zeleznik , Michael T. Lu , Hugo J. W. L. Aerts

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Sensitivity to staining variation remains a major barrier to deploying computational pathology (CPath) models as hematoxylin and eosin (H&E) staining varies across laboratories, requiring systematic assessment of how this variability…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Lydia A. Schönpflug , Nikki van den Berg , Sonali Andani , Nanda Horeweg , Jurriaan Barkey Wolf , Tjalling Bosse , Viktor H. Koelzer , Maxime W. Lafarge

4D CT imaging is an essential component of radiotherapy of thoracic/abdominal tumors. 4D CT images are, however, often affected by artifacts that compromise treatment planning quality. In this work, deep learning (DL)-based conditional…

Medical Physics · Physics 2024-11-26 Frederic Madesta , Thilo Sentker , Tobias Gauer , Rene Werner

Vision Transformer (ViT) is becoming widely popular in automating accurate disease diagnosis in medical imaging owing to its robust self-attention mechanism. However, ViTs remain vulnerable to adversarial attacks that may thwart the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Neha A S , Vivek Chaturvedi , Muhammad Shafique

Undersampled CT volumes minimize acquisition time and radiation exposure but introduce artifacts degrading image quality and diagnostic utility. Reducing these artifacts is critical for high-quality imaging. We propose a computationally…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Johannes Thalhammer , Tina Dorosti , Sebastian Peterhansl , Daniela Pfeiffer , Franz Pfeiffer , Florian Schaff

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

Motivation: Identifying the molecular pathways more prone to disruption during a pathological process is a key task in network medicine and, more in general, in systems biology. Results: In this work we propose a pipeline that couples a…

During the computed tomography (CT) imaging process, metallic implants within patients often cause harmful artifacts, which adversely degrade the visual quality of reconstructed CT images and negatively affect the subsequent clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Hong Wang , Yuexiang Li , Haimiao Zhang , Deyu Meng , Yefeng Zheng

Pathological features are the gold standard for tumor diagnosis, guiding treatment and prognosis. However, standard histopathological process is labor-intensive and time-consuming, while frozen sections have lower accuracy. Dynamic…

Mixture-of-Experts (MoE) has emerged as a promising architecture for modern large language models (LLMs). However, massive parameters impose heavy GPU memory (i.e., VRAM) demands, hindering the widespread adoption of MoE LLMs. Offloading…

Machine Learning · Computer Science 2025-09-11 Jiaming Yan , Jianchun Liu , Hongli Xu , Liusheng Huang

Numerous deep learning-based solutions have been proposed for histopathological image analysis over the past years. While they usually demonstrate exceptionally high accuracy, one key question is whether their precision might be affected by…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Andrey Ignatov , Grigory Malivenko

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Currently, industrial anomaly detection suffers from two bottlenecks: (i) the rarity of real-world defect images and (ii) the opacity of sample quality when synthetic data are used. Existing synthetic strategies (e.g., cut-and-paste)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Long Qian , Bingke Zhu , Yingying Chen , Ming Tang , Jinqiao Wang