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Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shuo Han , Ahmed Karam Eldaly , Solomon Sunday Oyelere

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

While microscopic analysis of histopathological slides is generally considered as the gold standard method for performing cancer diagnosis and grading, the current method for analysis is extremely time consuming and labour intensive as it…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Rene Bidart , Alexander Wong

Manual counting of mitotic tumor cells in tissue sections constitutes one of the strongest prognostic markers for breast cancer. This procedure, however, is time-consuming and error-prone. We developed a method to automatically detect…

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 So Won Jeong , Veronika Ročková

Rationale: Computer aided detection (CAD) algorithms for Pulmonary Embolism (PE) algorithms have been shown to increase radiologists' sensitivity with a small increase in specificity. However, CAD for PE has not been adopted into clinical…

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Histopathological image analysis is crucial for accurate cancer diagnosis and treatment planning. While deep learning models, especially convolutional neural networks, have advanced this field, their "black-box" nature raises concerns about…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Pardis Afshar , Sajjad Hashembeiki , Pouya Khani , Emad Fatemizadeh , Mohammad Hossein Rohban

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Intelligent fault-tolerant (FT) computing has recently demonstrated significant advantages in predicting and diagnosing faults proactively, thereby ensuring reliable service delivery. However, due to the heterogeneity of fault knowledge,…

Machine Learning · Computer Science 2025-12-15 Wenjing Xiao , Wenhao Song , Miaojiang Chen , Min Chen

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

Reproducibility of AI models on biomedical data still stays as a major concern for their acceptance into the clinical practice. Initiatives for reproducibility in the development of predictive biomarkers as the MAQC Consortium already…

Quantitative Methods · Quantitative Biology 2020-11-18 Nicole Bussola , Alessia Marcolini , Valerio Maggio , Giuseppe Jurman , Cesare Furlanello

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

Cone-beam computed tomography (CBCT) is a valuable imaging method in dental diagnostics that provides information not available in traditional 2D imaging. However, interpretation of CBCT images is a time-consuming process that requires a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Adel Zakirov , Matvey Ezhov , Maxim Gusarev , Vladimir Alexandrovsky , Evgeny Shumilov

We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…

In the field of transmission electron microscopy, data interpretation often lags behind acquisition methods, as image processing methods often have to be manually tailored to individual datasets. Machine learning offers a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 C. K. Groschner , Christina Choi , M. C. Scott

The formation of biomolecular materials via dynamical interfacial processes such as self-assembly and fusion, for diverse compositions and external conditions, can be efficiently probed using ensemble Molecular Dynamics. However, this…

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