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Due to their large sizes, volumetric scans and whole-slide pathology images (WSIs) are often processed by extracting embeddings from local regions and then an aggregator makes predictions from this set. However, current methods require…

Image and Video Processing · Electrical Eng. & Systems 2025-08-15 Wenbo Zhang , Junyu Chen , Christopher Kanan

The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity. Current CNN-Transformer hybrids use static…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Gia Huy Thai , Hoang-Nguyen Vu , Anh-Minh Phan , Quang-Thinh Ly , Tram Dinh , Thi-Ngoc-Truc Nguyen , Nhat Ho

Transformer has been widely used in histopathology whole slide image (WSI) classification for the purpose of tumor grading, prognosis analysis, etc. However, the design of token-wise self-attention and positional embedding strategy in the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yushan Zheng , Jun Li , Jun Shi , Fengying Xie , Zhiguo Jiang

Gigapixel image analysis, particularly for whole slide images (WSIs), often relies on multiple instance learning (MIL). Under the paradigm of MIL, patch image representations are extracted and then fixed during the training of the MIL…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Kunming Tang , Zhiguo Jiang , Jun Shi , Wei Wang , Haibo Wu , Yushan Zheng

Graph representation learning aims to effectively encode high-dimensional sparse graph-structured data into low-dimensional dense vectors, which is a fundamental task that has been widely studied in a range of fields, including machine…

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Learning-based methods have become increasingly popular for solving vehicle routing problems due to their near-optimal performance and fast inference speed. Among them, the combination of deep reinforcement learning and graph representation…

Machine Learning · Computer Science 2024-05-22 Zhenwei Wang , Ruibin Bai , Fazlullah Khan , Ender Ozcan , Tiehua Zhang

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practicality in diverse real-world applications. In healthcare,…

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Face parsing infers a pixel-wise label to each facial component, which has drawn much attention recently. Previous methods have shown their efficiency in face parsing, which however overlook the correlation among different face regions. The…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Gusi Te , Yinglu Liu , Wei Hu , Hailin Shi , Tao Mei

In this paper, we focus on graph representation learning of heterogeneous information network (HIN), in which various types of vertices are connected by various types of relations. Most of the existing methods conducted on HIN revise…

Machine Learning · Computer Science 2019-12-24 Huiting Hong , Hantao Guo , Yucheng Lin , Xiaoqing Yang , Zang Li , Jieping Ye

Graph representation learning is a fast-growing field where one of the main objectives is to generate meaningful representations of graphs in lower-dimensional spaces. The learned embeddings have been successfully applied to perform various…

Machine Learning · Computer Science 2021-12-21 Md. Khaledur Rahman , Ariful Azad

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

We propose a new method for embedding graphs while preserving directed edge information. Learning such continuous-space vector representations (or embeddings) of nodes in a graph is an important first step for using network information…

Machine Learning · Computer Science 2017-09-15 Sami Abu-El-Haija , Bryan Perozzi , Rami Al-Rfou

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud

The expensive fine-grained annotation and data scarcity have become the primary obstacles for the widespread adoption of deep learning-based Whole Slide Images (WSI) classification algorithms in clinical practice. Unlike few-shot learning…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Kexue Fu , Xiaoyuan Luo , Linhao Qu , Shuo Wang , Ying Xiong , Ilias Maglogiannis , Longxiang Gao , Manning Wang

Automated pathology report generation from Whole Slide Images (WSIs) faces two key challenges: (1) lack of semantic content in visual features and (2) inherent information redundancy in WSIs. To address these issues, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Ling Zhang , Boxiang Yun , Qingli Li , Yan Wang

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan
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