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Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in…

Machine Learning · Computer Science 2019-08-14 Vikram Venkatraghavan , Esther E. Bron , Wiro J. Niessen , Stefan Klein

Background: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients,…

Machine Learning · Computer Science 2024-08-09 Candi Zheng , Kun Liu , Yang Wang , Shiyi Chen , Hongli Li

Background: Artificial intelligence (AI) models in healthcare depend on the fidelity of diagnostic data, yet the quality of such data is often compromised by variability in clinical documentation practices. In dementia, a condition already…

Purpose: To construct a neural network model that can learn the different diagnosing strategies of radiologists to better classify aneurysm status in magnetic resonance angiography images. Materials and methods: This retrospective study…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Yasuhiko Tachibana , Masataka Nishimori , Naoyuki Kitamura , Kensuke Umehara , Junko Ota , Takayuki Obata , Tatsuya Higashi

Alzheimer's Disease (AD) is marked by significant inter-individual variability in its progression, complicating accurate prognosis and personalized care planning. This heterogeneity underscores the critical need for predictive models…

Machine Learning · Computer Science 2025-05-01 Gulsah Hancerliogullari Koksalmis , Bulent Soykan , Laura J. Brattain , Hsin-Hsiung Huang

Predicting extubation failure in intensive care is challenging due to complex data and the severe consequences of inaccurate predictions. Machine learning shows promise in improving clinical decision-making but often fails to account for…

Machine Learning · Computer Science 2024-12-03 Akram Yoosoofsah

Predicting future disease progression risk from medical images is challenging due to patient heterogeneity, and subtle or unknown imaging biomarkers. Moreover, deep learning (DL) methods for survival analysis are susceptible to image domain…

Chronic obstructive pulmonary disease (COPD) represents a significant global health burden, where precise severity assessment is particularly critical for effective clinical management in intensive care unit (ICU) settings. This study…

Machine Learning · Computer Science 2025-04-29 Akram Shojaei , Mehdi Delrobaei

Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

Extensive bedside monitoring in Intensive Care Units (ICUs) has resulted in complex temporal data regarding patient physiology, which presents an upscale context for clinical data analysis. In the other hand, identifying the time-series…

Machine Learning · Computer Science 2023-08-25 Manel Mili , Asma Kerkeni , Asma Ben Abdallah , Mohamed Hedi Bedoui

Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…

Machine Learning · Computer Science 2025-04-29 Rumeng Li , Xun Wang , Dan Berlowitz , Brian Silver , Wen Hu , Heather Keating , Raelene Goodwin , Weisong Liu , Honghuang Lin , Hong Yu

Predicting user preferences and sequential dependencies based on historical behavior is the core goal of sequential recommendation. Although attention-based models have shown effectiveness in this field, they often struggle with inference…

Machine Learning · Computer Science 2024-06-11 Yuda Wang , Xuxin He , Shengxin Zhu

The brain-age gap is one of the most investigated risk markers for brain changes across disorders. While the field is progressing towards large-scale models, recently incorporating uncertainty estimates, no model to date provides the…

Major depressive disorder (MDD), a leading cause of disability and mortality, is associated with reward-processing abnormalities and concentration issues. Motivated by the probabilistic reward task from the Establishing Moderators and…

Methodology · Statistics 2026-02-23 Yuan Bian , Xingche Guo , Yuanjia Wang

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Suryansh Vidya , Kush Gupta , Amir Aly , Andy Wills , Emmanuel Ifeachor , Rohit Shankar

Human engagement estimation in conversational scenarios is essential for applications such as adaptive tutoring, remote healthcare assessment, and socially aware human--computer interaction. Engagement is a dynamic, multimodal signal…

Artificial Intelligence · Computer Science 2025-09-23 Shenwei Kang , Xin Zhang , Wen Liu , Bin Li , Yujie Liu , Bo Gao

Unsupervised Continuous Anomaly Detection (UCAD) is gaining attention for effectively addressing the catastrophic forgetting and heavy computational burden issues in traditional Unsupervised Anomaly Detection (UAD). However, existing UCAD…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Mingle Zhou , Jiahui Liu , Jin Wan , Gang Li , Min Li

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

Machine Learning · Computer Science 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Early recognition of clinical deterioration is one of the main steps for reducing inpatient morbidity and mortality. The challenging task of clinical deterioration identification in hospitals lies in the intense daily routines of healthcare…