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Machine learning and quantum computing are two technologies each with the potential for altering how computation is performed to address previously untenable problems. Kernel methods for machine learning are ubiquitous for pattern…

The main goal of this master's thesis is to introduce Quantum Natural Language Processing (QNLP) in a way understandable by both the NLP engineer and the quantum computing practitioner. QNLP is a recent application of quantum computing that…

Computation and Language · Computer Science 2022-02-25 Shervin Le Du , Senaida Hernández Santana , Giannicola Scarpa

Quantum machine learning is considered one of the current research fields with immense potential. In recent years, Havl\'i\v{c}ek et al. [Nature 567, 209-212 (2019)] have proposed a quantum machine learning algorithm with quantum-enhanced…

Quantum Physics · Physics 2025-06-09 Chao Ding , Shi Wang , Yaonan Wang , Weibo Gao

The knowledge regarding the function of proteins is necessary as it gives a clear picture of biological processes. Nevertheless, there are many protein sequences found and added to the databases but lacks functional annotation. The…

Quantitative Methods · Quantitative Biology 2018-09-13 Anu Vazhayil , Vinayakumar R , Soman KP

Advances in classical machine learning and single-cell technologies have paved the way to understand interactions between disease cells and tumor microenvironments to accelerate therapeutic discovery. However, challenges in these machine…

Quantum Physics · Physics 2023-10-18 Anupama Ray , Dhiraj Madan , Srushti Patil , Maria Anna Rapsomaniki , Pushpak Pati

In the present article, we propose a paradigm shift on evolving Artificial Neural Networks (ANNs) towards a new bio-inspired design that is grounded on the structural properties, interactions, and dynamics of protein networks (PNs): the…

Neural and Evolutionary Computing · Computer Science 2024-06-10 Oscar Lao , Konstantinos Zacharopoulos , Apostolos Fournaris , Rossano Schifanella , Ioannis Arapakis

Attention mechanisms have revolutionized natural language processing. Combining them with quantum computing aims to further advance this technology. This paper introduces a novel Quantum Mixed-State Self-Attention Network (QMSAN) for…

Quantum Physics · Physics 2024-12-03 Fu Chen , Qinglin Zhao , Li Feng , Chuangtao Chen , Yangbin Lin , Jianhong Lin

Machine learning algorithms perform well on identifying patterns in many different datasets due to their versatility. However, as one increases the size of the dataset, the computation time for training and using these statistical models…

Quantum Physics · Physics 2024-09-19 Abhijat Sarma , Rupak Chatterjee , Kaitlin Gili , Ting Yu

Tensor Network (TN) Kernel Machines speed up model learning by representing parameters as low-rank TNs, reducing computation and memory use. However, most TN-based Kernel methods are deterministic and ignore parameter uncertainty. Further,…

Machine Learning · Statistics 2025-07-16 Afra Kilic , Kim Batselier

Machine learning has been applied on a wide variety of models, from classical statistical mechanics to quantum strongly correlated systems for the identification of phase transitions. The recently proposed quantum convolutional neural…

Strongly Correlated Electrons · Physics 2021-11-10 Nathaniel Wrobel , Anshumitra Baul , Juana Moreno , Ka-Ming Tam

With the exponential increase of the protein sequence databases over time, multiple-sequence alignment (MSA) methods, like PSI-BLAST, perform exhaustive and time-consuming database search to retrieve evolutionary information. The resulting…

Quantitative Methods · Quantitative Biology 2023-08-21 Issar Arab

With near-term quantum devices available and the race for fault-tolerant quantum computers in full swing, researchers became interested in the question of what happens if we replace a supervised machine learning model with a quantum…

Quantum Physics · Physics 2021-04-20 Maria Schuld

Hybrid quantum-classical classifiers promise to positively impact critical aspects of natural language processing tasks, particularly classification-related ones. Among the possibilities currently investigated, quantum transfer learning,…

Computation and Language · Computer Science 2024-01-17 Giuseppe Buonaiuto , Raffaele Guarasci , Aniello Minutolo , Giuseppe De Pietro , Massimo Esposito

Quantum neural networks are deemed suitable to replace classical neural networks in their ability to learn and scale up network models using quantum-exclusive phenomena like superposition and entanglement. However, in the noisy intermediate…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Dibyasree Guha , Shyamali Mitra , Somenath Kuiry , Nibaran Das

Over the past decade, machine learning revolutionized vision-based quality assessment for which convolutional neural networks (CNNs) have now become the standard. In this paper, we consider a potential next step in this development and…

Quantum Physics · Physics 2022-06-09 Barry D. Reese , Marek Kowalik , Christian Metzl , Christian Bauckhage , Eldar Sultanow

Large protein language models are adept at capturing the underlying evolutionary information in primary structures, offering significant practical value for protein engineering. Compared to natural language models, protein amino acid…

Computation and Language · Computer Science 2023-10-27 Yang Tan , Mingchen Li , Pan Tan , Ziyi Zhou , Huiqun Yu , Guisheng Fan , Liang Hong

The 21st century is presenting humankind with unprecedented environmental and medical challenges. The ability to design novel proteins tailored for specific purposes could transform our ability to respond timely to these issues. Recent…

Biomolecules · Quantitative Biology 2022-08-24 Noelia Ferruz , Birte Höcker

Deep neural networks, particularly Transformers, have been widely adopted for predicting the functional properties of proteins. In this work, we focus on exploring whether Protein Transformers can capture biological intelligence among…

Machine Learning · Computer Science 2025-06-10 Fudong Lin , Wanrou Du , Jinchan Liu , Tarikul Milon , Shelby Meche , Wu Xu , Xiaoqi Qin , Xu Yuan

Quantum computing, leveraging principles of quantum mechanics, represents a transformative approach in computational methodologies, offering significant enhancements over traditional classical systems. This study tackles the complex and…

Quantum Physics · Physics 2024-05-21 Mohammadreza Soltaninia , Junpeng Zhan

Protein-nucleic acid interactions play a very important role in a variety of biological activities. Accurate identification of nucleic acid-binding residues is a critical step in understanding the interaction mechanisms. Although many…

Quantitative Methods · Quantitative Biology 2024-01-23 Wenwu Zeng , Dafeng Lv , Wenjuan Liu , Shaoliang Peng