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We introduce a quantum neural network, QNN, that can represent labeled data, classical or quantum, and be trained by supervised learning. The quantum circuit consists of a sequence of parameter dependent unitary transformations which acts…

Quantum Physics · Physics 2018-09-03 Edward Farhi , Hartmut Neven

Tensor Networks have emerged as a prominent alternative to neural networks for addressing Machine Learning challenges in foundational sciences, paving the way for their applications to real-life problems. This paper introduces tn4ml, a…

We present a quantum computing approach to analyzing Large Language Model (LLM) embeddings, leveraging complex-valued representations and modeling semantic relationships using quantum mechanical principles. By establishing a direct mapping…

Quantum Physics · Physics 2025-12-03 Timo Aukusti Laine

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

Quantum Neural Networks (QNNs), a prominent approach in Quantum Machine Learning (QML), are emerging as a powerful alternative to classical machine learning methods. Recent studies have focused on the applicability of QNNs to various tasks,…

Machine Learning · Computer Science 2025-07-01 Batuhan Hangun , Oguz Altun , Onder Eyecioglu

Predicting the three-dimensional (3D) structure of a protein from its primary sequence of amino acids is known as the protein folding (PF) problem. Due to the central role of proteins' 3D structures in chemistry, biology and medicine…

Quantum Physics · Physics 2021-03-18 Anton Robert , Panagiotis Kl. Barkoutsos , Stefan Woerner , Ivano Tavernelli

We demonstrate the feasibility of framing a classically learned deep neural network as an energy based model that can be processed on a one-step quantum annealer in order to exploit fast sampling times. We propose approaches to overcome two…

Quantum Physics · Physics 2021-07-20 Catherine F. Higham , Adrian Bedford

We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein sequencing relies on mass spectrometry, with some novel edman degregation based…

Quantum algorithms based on quantum kernel methods have been investigated previously [1]. A quantum advantage is derived from the fact that it is possible to construct a family of datasets for which, only quantum processing can recognise…

Quantum Physics · Physics 2024-05-08 Sanjeev Naguleswaran

According to the statistical interpretation of quantum theory, quantum computers form a distinguished class of probabilistic machines (PMs) by encoding n qubits in 2n pbits (random binary variables). This raises the possibility of a…

Quantum Physics · Physics 2007-05-23 P. Gralewicz

Quantum-inspired neural network is one of the interesting researches at the junction of the two fields of quantum computing and deep learning. Several models of quantum-inspired neurons with real parameters have been proposed, which are…

Quantum natural language processing (QNLP) offers a novel approach to semantic modeling by embedding compositional structure directly into quantum circuits. This paper investigates the application of QNLP models to the task of Natural…

Computation and Language · Computer Science 2025-10-21 Ling Sun , Peter Sullivan , Michael Martin , Yun Zhou

Circuit knitting offers a promising path to the scalable execution of large quantum circuits by breaking them into smaller sub-circuits whose output is recombined through classical postprocessing. However, current techniques face excessive…

Quantum Physics · Physics 2024-10-22 Nathaniel Tornow , Christian B. Mendl , Pramod Bhatotia

Quantum and quantum-inspired machine learning has emerged as a promising and challenging research field due to the increased popularity of quantum computing, especially with near-term devices. Theoretical contributions point toward…

Quantum Physics · Physics 2023-12-08 C. Moussa , H. Wang , M. Araya-Polo , T. Bäck , V. Dunjko

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

Breast cancer diagnosis through thermographic image analysis remains a critical challenge in medical AI, with classical deep learning approaches facing limitations in complex thermal pattern classification tasks. This paper presents a novel…

The use of advanced quantum neuron models for pattern recognition applications requires fault tolerance. Therefore, it is not yet possible to test such models on a large scale in currently available quantum processors. As an alternative, we…

Quantum Physics · Physics 2022-02-18 London A. Cavaletto , Luca Candelori , Alex Matos-Abiague

Modern machine learning (ML) systems excel in recognising and classifying images with remarkable accuracy. However, like many computer software systems, they can fail by generating confusing or erroneous outputs or by deferring to human…

Machine Learning · Computer Science 2024-12-12 Milan Maksimovic , Ivan S. Maksymov