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Related papers: Guiding Clinical Reasoning with Large Language Mod…

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The continued success of Large Language Models (LLMs) and other generative artificial intelligence approaches highlights the advantages that large information corpora can have over rigidly defined symbolic models, but also serves as a…

Large language models (LLMs) often struggle with complex mathematical tasks, prone to "hallucinating" incorrect answers due to their reliance on statistical patterns. This limitation is further amplified in average Small LangSLMs with…

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

Computation and Language · Computer Science 2026-01-21 Kie Shidara , Preethi Prem , Jonathan Kim , Anna Podlasek , Feng Liu , Ahmed Alaa , Danilo Bernardo

A seminal paper published by Ledley and Lusted in 1959 introduced complex clinical diagnostic reasoning cases as the gold standard for the evaluation of expert medical computing systems, a standard that has held ever since. Here, we report…

Inductive reasoning is an essential capability for large language models (LLMs) to achieve higher intelligence, which requires the model to generalize rules from observed facts and then apply them to unseen examples. We present MIRAGE, a…

Computation and Language · Computer Science 2025-03-03 Jiachun Li , Pengfei Cao , Zhuoran Jin , Yubo Chen , Kang Liu , Jun Zhao

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria

A central goal of cognitive science is to provide a computationally explicit account of both the structure of the mind and its development: what are the primitive representational building blocks of cognition, what are the rules via which…

Artificial Intelligence · Computer Science 2025-07-08 Alyssa Loo , Ellie Pavlick , Roman Feiman

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

The rapid advancements in large Language models (LLMs) have significantly enhanced their reasoning capabilities, driven by various strategies such as multi-agent collaboration. However, unlike the well-established performance improvements…

Artificial Intelligence · Computer Science 2026-04-23 Zihan Chen , Song Wang , Zhen Tan , Xingbo Fu , Zhenyu Lei , Peng Wang , Huan Liu , Cong Shen , Jundong Li

Language serves as a vehicle for conveying thought, enabling communication among individuals. The ability to distinguish between diverse concepts, identify fairness and injustice, and comprehend a range of legal notions fundamentally relies…

Computation and Language · Computer Science 2023-11-23 Ha-Thanh Nguyen , Wachara Fungwacharakorn , Ken Satoh

Large language models (LLMs) have shown an impressive ability to perform tasks believed to require thought processes. When the model does not document an explicit thought process, it becomes difficult to understand the processes occurring…

Computation and Language · Computer Science 2024-06-21 Yuval Shalev , Amir Feder , Ariel Goldstein

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

The integration of Large Language Models (LLMs) into healthcare holds significant potential to enhance diagnostic accuracy and support medical treatment planning. These AI-driven systems can analyze vast datasets, assisting clinicians in…

Computation and Language · Computer Science 2025-04-15 Diogo Sousa , Guilherme Barbosa , Catarina Rocha , Dulce Oliveira

Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…

Computation and Language · Computer Science 2026-04-28 Yimin Deng , Zhenxi Lin , Yejing Wang , Guoshuai Zhao , Pengyue Jia , Zichuan Fu , Derong Xu , Yefeng Zheng , Xiangyu Zhao , Li Zhu , Xian Wu , Xueming Qian

Analogical reasoning -- the capacity to identify and map structural relationships between different domains -- is fundamental to human cognition and learning. Recent studies have shown that large language models (LLMs) can sometimes match…

Computation and Language · Computer Science 2025-11-21 Sam Musker , Alex Duchnowski , Raphaël Millière , Ellie Pavlick

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

Large language models (LLMs) are powerful artificial intelligence (AI) tools transforming how research is conducted. However, their use in research has been met with skepticism, due to concerns about hallucinations, biases and potential…

Artificial Intelligence · Computer Science 2025-07-08 Ruian Ke , Ruy M. Ribeiro