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Graph Neural Networks (GNNs) have shown great superiority on non-Euclidean graph data, achieving ground-breaking performance on various graph-related tasks. As a practical solution to train GNN on large graphs with billions of nodes and…

Machine Learning · Computer Science 2024-09-24 Zeyu Zhu , Peisong Wang , Qinghao Hu , Gang Li , Xiaoyao Liang , Jian Cheng

The work for predicting drug and target affinity(DTA) is crucial for drug development and repurposing. In this work, we propose a novel method called GDGRU-DTA to predict the binding affinity between drugs and targets, which is based on…

Quantitative Methods · Quantitative Biology 2022-04-27 Lyu Zhijian , Jiang Shaohua , Liang Yigao , Gao Min

In the realm of Text-attributed Graphs (TAGs), traditional graph neural networks (GNNs) often fall short due to the complex textual information associated with each node. Recent methods have improved node representations by leveraging large…

Machine Learning · Computer Science 2025-06-10 Huanyi Xie , Lijie Hu , Lu Yu , Tianhao Huang , Longfei Li , Meng Li , Jun Zhou , Huan Wang , Di Wang

Achieving high performance for GPU codes requires developers to have significant knowledge in parallel programming and GPU architectures, and in-depth understanding of the application. This combination makes it challenging to find…

Software Engineering · Computer Science 2022-08-29 Jhe-Yu Liou , Muaaz Awan , Steven Hofmeyr , Stephanie Forrest , Carole-Jean Wu

Motivation: Read mapping is a computationally expensive process and a major bottleneck in genomics analyses. The performance of read mapping is mainly limited by the performance of three key computational steps: Index Querying, Seed…

Hardware Architecture · Computer Science 2023-10-02 Julien Eudine , Mohammed Alser , Gagandeep Singh , Can Alkan , Onur Mutlu

Program synthesis is an umbrella term for generating programs and logical formulae from specifications. With the remarkable performance improvements that GPUs enable for deep learning, a natural question arose: can we also implement a…

Programming Languages · Computer Science 2025-04-29 Martin Berger , Nathanaël Fijalkow , Mojtaba Valizadeh

Genetic Algorithms (GAs) are known for their efficiency in solving combinatorial optimization problems, thanks to their ability to explore diverse solution spaces, handle various representations, exploit parallelism, preserve good…

Neural and Evolutionary Computing · Computer Science 2023-09-29 Majid Sohrabi , Amir M. Fathollahi-Fard , Vasilii A. Gromov

Approximate nearest neighbor (ANN) search in high dimensions is an integral part of several computer vision systems and gains importance in deep learning with explicit memory representations. Since PQT, FAISS, and SONG started to leverage…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Fabian Groh , Lukas Ruppert , Patrick Wieschollek , Hendrik P. A. Lensch

Process mapping asks to assign vertices of a task graph to processing elements of a supercomputer such that the computational workload is balanced while the communication cost is minimized. Motivated by the recent success of GPU-based graph…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-16 Petr Samoldekin , Christian Schulz , Henning Woydt

High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS…

Hardware Architecture · Computer Science 2023-06-01 Onur Mutlu , Can Firtina

Based on SGD, previous works have proposed many algorithms that have improved convergence speed and generalization in stochastic optimization, such as SGDm, AdaGrad, Adam, etc. However, their convergence analysis under non-convex conditions…

Machine Learning · Computer Science 2024-02-05 Yichuan Deng , Zhao Song , Chiwun Yang

Gait recognition is emerging as a promising and innovative area within the field of computer vision, widely applied to remote person identification. Although existing gait recognition methods have achieved substantial success in controlled…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Zhengxian Wu , Chuanrui Zhang , Hangrui Xu , Peng Jiao , Haoqian Wang

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…

Quantum Physics · Physics 2020-05-22 Aritra Sarkar , Zaid Al-Ars , Carmen G. Almudever , Koen Bertels

In this paper, we present CT-AGD (Curvature-Tuned Accelerated Gradient Descent), an optimization method for non-convex optimization problems in deep learning training tasks. CT-AGD is a general boosting procedure that accelerates…

Machine Learning · Computer Science 2026-05-18 Manuel Graca , L. Miguel Silveira , Arlindo Oliveira , Frank Liu

We present a set of rules to guide the design of GPU algorithms. These rules are grounded on the principle of reducing waste in GPU utility to achieve good speed up. In accordance to these rules, we propose GPU algorithms for 2D…

Graphics · Computer Science 2020-07-02 Zhenghai Chen , Tiow-Seng Tan , Hong-Yang Ong

Similarity search, the task of identifying objects most similar to a given query object under a specific metric, has gathered significant attention due to its practical applications. However, the absence of coordinate information to…

Databases · Computer Science 2024-05-14 Yifan Zhu , Ruiyao Ma , Baihua Zheng , Xiangyu Ke , Lu Chen , Yunjun Gao

In this paper, we propose a new algorithm to speed-up the convergence of accelerated proximal gradient (APG) methods. In order to minimize a convex function $f(\mathbf{x})$, our algorithm introduces a simple line search step after each…

Machine Learning · Statistics 2014-06-19 Ziming Zhang , Venkatesh Saligrama

The Random Phase Approximation (RPA) for correlation energy in the grid-based projector augmented wave (gpaw) code is accelerated by porting to the Graphics Processing Unit (GPU) architecture. The acceleration is achieved by grouping…

Computational Physics · Physics 2013-07-31 Jun Yan , Lin Li , Christopher O'Grady

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk
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