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In recent times, substantial advancements have been witnessed in large language models (LLMs), exemplified by ChatGPT, showcasing remarkable proficiency across a range of complex tasks. However, many mainstream LLMs (e.g. LLaMA) are…

Computation and Language · Computer Science 2024-01-15 Jun Zhao , Zhihao Zhang , Luhui Gao , Qi Zhang , Tao Gui , Xuanjing Huang

Biomedical literature often uses complex language and inaccessible professional terminologies. That is why simplification plays an important role in improving public health literacy. Applying Natural Language Processing (NLP) models to…

Computation and Language · Computer Science 2024-03-19 Zihao Li , Samuel Belkadi , Nicolo Micheletti , Lifeng Han , Matthew Shardlow , Goran Nenadic

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

Objective: to provide a scoping review of papers on clinical natural language processing (NLP) tasks that use publicly available electronic health record data from a cohort of patients. Materials and Methods: We searched six databases,…

Language models are widely used in chemistry for molecular property prediction and small-molecule generation, yet Natural Products (NPs) remain underexplored despite their importance in drug discovery. To address this gap, we develop…

Machine Learning · Computer Science 2026-02-17 Ho-Hsuan Wang , Afnan Sultan , Andrea Volkamer , Dietrich Klakow

Clinical time-series data are difficult to model with methods designed for regular sequences because they exhibit irregular sampling, frequent missing values, and heterogeneous observation patterns across variables. Existing approaches…

Machine Learning · Computer Science 2026-05-19 Jinwoong Kim , Sangjin Park

The Transformer architecture has shown a remarkable ability in modeling global relationships. However, it poses a significant computational challenge when processing high-dimensional medical images. This hinders its development and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Zhaohu Xing , Tian Ye , Yijun Yang , Guang Liu , Lei Zhu

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Clinical trials are a critical process in the medical field for introducing new treatments and innovations. However, cohort selection for clinical trials is a time-consuming process that often requires manual review of patient text records…

Computation and Language · Computer Science 2025-01-22 Chi-en Amy Tai , Xavier Tannier

Medical reports contain rich clinical information but are often unstructured and written in domain-specific language, posing challenges for information extraction. While proprietary large language models (LLMs) have shown promise in…

Computation and Language · Computer Science 2026-03-12 Luc Builtjes , Joeran Bosma , Mathias Prokop , Bram van Ginneken , Alessa Hering

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome…

Computation and Language · Computer Science 2023-01-30 Yanjun Gao , Dmitriy Dligach , Timothy Miller , John Caskey , Brihat Sharma , Matthew M Churpek , Majid Afshar

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

Convolutional neural networks (CNNs) and transformers are widely employed in constructing UNet architectures for medical image segmentation tasks. However, CNNs struggle to model long-range dependencies, while transformers suffer from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Shaolei Zhang , Jinyan Liu , Tianyi Qian , Xuesong Li

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of…

Language models serve as a cornerstone in natural language processing (NLP), utilizing mathematical methods to generalize language laws and knowledge for prediction and generation. Over extensive research spanning decades, language modeling…

Computation and Language · Computer Science 2024-09-24 Zichong Wang , Zhibo Chu , Thang Viet Doan , Shiwen Ni , Min Yang , Wenbin Zhang

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare…

The typical Selective State-Space Model (SSM) used in Mamba addresses several limitations of Transformers, such as the quadratic computational complexity with respect to sequence length and the significant memory requirements during…

Computation and Language · Computer Science 2025-10-24 Shengkun Tang , Liqun Ma , Haonan Li , Mingjie Sun , Zhiqiang Shen
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