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Pre-trained language models (PLMs) have been the de facto paradigm for most natural language processing (NLP) tasks. This also benefits biomedical domain: researchers from informatics, medicine, and computer science (CS) communities propose…

Computation and Language · Computer Science 2023-07-18 Benyou Wang , Qianqian Xie , Jiahuan Pei , Zhihong Chen , Prayag Tiwari , Zhao Li , Jie fu

This paper presents a Lisp architecture for a portable NLP system, termed LAPNLP, for processing clinical notes. LAPNLP integrates multiple standard, customized and in-house developed NLP tools. Our system facilitates portability across…

Computation and Language · Computer Science 2018-11-16 Yuan Luo , Peter Szolovits

Writing clinical notes and documenting medical exams is a critical task for healthcare professionals, serving as a vital component of patient care documentation. However, manually writing these notes is time-consuming and can impact the…

Computation and Language · Computer Science 2025-06-17 Yizhan Li , Sifan Wu , Christopher Smith , Thomas Lo , Bang Liu

Scribble annotations significantly reduce the cost and labor required for dense labeling in large medical datasets with complex anatomical structures. However, current scribble-supervised learning methods are limited in their ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Luyi Qiu , Tristan Till , Xiaobao Guo , Adams Wai-Kin Kong

Large Language Models (LLMs) consistently excel in diverse medical Natural Language Processing (NLP) tasks, yet their substantial computational requirements often limit deployment in real-world healthcare settings. In this work, we…

Computation and Language · Computer Science 2026-02-20 Pietro Ferrazzi , Mattia Franzin , Alberto Lavelli , Bernardo Magnini

Long-range sequence processing poses a significant challenge for Transformers due to their quadratic complexity in input length. A promising alternative is Mamba, which demonstrates high performance and achieves Transformer-level…

Machine Learning · Computer Science 2025-04-11 Assaf Ben-Kish , Itamar Zimerman , Shady Abu-Hussein , Nadav Cohen , Amir Globerson , Lior Wolf , Raja Giryes

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Multimodal Large Language Models (MLLMs) have attracted much attention for their multifunctionality. However, traditional Transformer architectures incur significant overhead due to their secondary computational complexity. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Wenjun Huang , Jiakai Pan , Jiahao Tang , Yanyu Ding , Yifei Xing , Yuhe Wang , Zhengzhuo Wang , Jianguo Hu

We present Clinical Camel, an open large language model (LLM) explicitly tailored for clinical research. Fine-tuned from LLaMA-2 using QLoRA, Clinical Camel achieves state-of-the-art performance across medical benchmarks among openly…

Computation and Language · Computer Science 2023-08-21 Augustin Toma , Patrick R. Lawler , Jimmy Ba , Rahul G. Krishnan , Barry B. Rubin , Bo Wang

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

Clinical documentation is a critical factor for patient safety, diagnosis, and continuity of care. The administrative burden of EHRs is a significant factor in physician burnout. This is a critical issue for low-resource languages,…

Computation and Language · Computer Science 2026-03-27 Mohammed Nowshad Ruhani Chowdhury , Mohammed Nowaz Rabbani Chowdhury , Sakari Lukkarinen

With the evolution of large language models, traditional Transformer models become computationally demanding for lengthy sequences due to the quadratic growth in computation with respect to the sequence length. Mamba, emerging as a…

Machine Learning · Computer Science 2024-08-22 Haoran Xu , Ziqian Liu , Rong Fu , Zhongling Su , Zerui Wang , Zheng Cai , Zhilin Pei , Xingcheng Zhang

Large Language Models (LLMs) hold great promise to revolutionize current clinical systems for their superior capacities on medical text processing tasks and medical licensing exams. Meanwhile, traditional ML models such as SVM and XGBoost…

Computation and Language · Computer Science 2024-11-12 Canyu Chen , Jian Yu , Shan Chen , Che Liu , Zhongwei Wan , Danielle Bitterman , Fei Wang , Kai Shu

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

Computation and Language · Computer Science 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Linear RNN architectures, like Mamba, can be competitive with Transformer models in language modeling while having advantageous deployment characteristics. Given the focus on training large-scale Transformer models, we consider the…

Machine Learning · Computer Science 2025-06-30 Junxiong Wang , Daniele Paliotta , Avner May , Alexander M. Rush , Tri Dao

Foundation Models (FMs) trained on Electronic Health Records (EHRs) have achieved state-of-the-art results on numerous clinical prediction tasks. However, most existing EHR FMs have context windows of <1k tokens. This prevents them from…