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The lack of molecular-level understanding for the electronic excitation response of DNA to charged particle radiation, such as high-energy protons, remains a fundamental scientific bottleneck in advancing proton and other ion beam cancer…

Soft Condensed Matter · Physics 2023-03-17 Christopher Shepard , Dillon Yost , Yosuke Kanai

We develop an analytical theory that accounts for the image and surface charge interactions between a charged dielectric membrane and a DNA molecule translocating through the membrane. Translocation events through neutral carbon-based…

Soft Condensed Matter · Physics 2016-08-03 Sahin Buyukdagli , T. Ala-Nissila

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

The electrical properties of DNA molecules are investigated by charge injection and electric force microscopy experiments. Prior to injection, DNA molecules exhibit a weak positively charged state. We probe the electrical behaviour of DNA…

Materials Science · Physics 2009-11-10 Thomas Heim , Thierry Melin , Dominique Deresmes , Dominique Vuillaume

The response of a semiflexible polyelectrolyte chain to stretching in the regimes of moderate and weak screening is studied theoretically, with a special focus on DNA experiments. By using the nonlinear Poisson--Boltzmann description of…

Soft Condensed Matter · Physics 2007-05-23 Alexei V. Tkachenko

The effect of electrostatic interactions on the stretching of DNA is investigated using a simple worm like chain model. In the limit of small force there are large conformational fluctuations which are treated using a self-consistent…

Soft Condensed Matter · Physics 2009-10-31 Namkyung Lee , D. Thirumalai

The adsorption of DNA or other polyelectrolyte molecules on charged membranes is a recurrent motif in soft matter and bionanotechnological systems. Two typical situations encountered are the deposition of single DNA chains onto substrates…

Soft Condensed Matter · Physics 2016-10-19 Sahin Buyukdagli , Ralf Blossey

Due to its polyionic character the DNA double helix is stable and biologically active only in salty aqueous media where its charge is compensated by solvent counterions. Monovalent metal ions are ubiquitous in DNA environment and they are…

Biological Physics · Physics 2007-05-23 Alexey K. Mazur

A study of a model rod-like polyelectrolyte molecule immersed into a monovalent or divalent electrolyte is presented. Results from the hypernetted-chain/mean spherical approximation (HNC/MSA) theory, for inhomogeneous charged fluids, {\ch…

Soft Condensed Matter · Physics 2007-05-23 Markus Deserno , Felipe Jimenez-Angeles , Christian Holm , Marcelo Lozada-Cassou

When the DNA double helix is subjected to external forces it can stretch elastically to elongations reaching 100% of its natural length. These distortions, imposed at the mesoscopic or macroscopic scales, have a dramatic effect on…

Materials Science · Physics 2009-11-13 Ryan Barnett , Paul Maragakis , Ari Turner , Maria Fyta , Efthimios Kaxiras

Microscopic mechanisms of positive charge transfer in DNA remain unclear. A quantum state of electron hole in DNA is determined by the competition of a pi-stacking interaction $b$ smearing a charge between different base pairs and…

Soft Condensed Matter · Physics 2008-03-15 D. B. Uskov , A. L. Burin

Charge diffusion through desoxyribonucleic acid (DNA) is a physico-chemical phenomenon that on the one hand is being explored for technological purposes, on the other hand is applied by nature for various informational processes in life.…

Biological Physics · Physics 2024-07-22 Mirko Rossini , Ole Ammerpohl , Reiner Siebert , Joachim Ankerhold

DNA is an essential molecule central to the survival and propagation of life, it was imperative to investigate possible electromagnetic properties inherent to it, such as the existence of any non-trivial interactions of this molecule with…

Biological Physics · Physics 2017-04-25 M. H. S. Bukhari , Y. Raza , S. Batool , T. Razzaki , A. Bukhari , F. Memon , M. A. Rauf , A. Rizvi , O. Bagasra

The electrodynamic response of DNA in the millimeter wave range is investigated. By performing measurements under a wide range of humidity conditions and comparing the response of single strand DNA and double strand DNA, we show that the…

Disordered Systems and Neural Networks · Physics 2015-06-24 M. Briman , N. P. Armitage , E. Helgren , G. Gruner

We consider voltage-driving DNA translocation through a nanopore in the present study. By assuming the DNA is coaxial with the cylindrical nanopore, a hydrodynamic model for determining effective force on a single DNA molecule in a nanopore…

Soft Condensed Matter · Physics 2013-06-19 Wen-Yue Tang , Guo-Hui Hu

Understanding how the electronic excitation of DNA changes in response to different high-energy particles is central to advancing ion beam cancer therapy. While protons have been the predominant ion of choice in beam cancer therapy, heavier…

Soft Condensed Matter · Physics 2024-01-10 Christopher Shepard , Yosuke Kanai

Microscopic mechanisms of positive charge transfer in DNA remain unclear. A quantum state of electron hole in DNA is determined by the competition of the pi-stacking interaction $b$ sharing a charge between different base pairs and the…

Soft Condensed Matter · Physics 2008-06-06 Dmitry B. Uskov , Alexander L. Burin

Numerous experiments on charge transfer in DNA yield a contradictory picture of the transfer: on the one hand they suggest that it is a very slow process and the charge is almost completely localized on one Watson-Crick pair, but on the…

Biological Physics · Physics 2013-04-22 V. D. Lakhno , V. B. Sultanov

Strong influence of water molecules on the transport and magnetic properties of DNA, observed in this study, opens up real opportunities for application of DNA in molecular electronics. Interaction of the nucleobases with water molecules…

Chemical Physics · Physics 2010-08-13 Julia Berashevich , Tapash Chakraborty

The high linear charge density of 20-base-pair oligomers of DNA is shown to lead to a striking non-monotonic dependence of the long-time self-diffusion on the concentration of the DNA in low-salt conditions. This generic non-monotonic…

Soft Condensed Matter · Physics 2009-11-13 M. G. McPhie , G. Naegele
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