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As a specific proportional hazard rates model, sequential order statistics can be used to describe the lifetimes of load-sharing systems. Inference for these systems needs to account for small sample sizes, which are prevalent in…

Methodology · Statistics 2019-09-17 Fabian Mies , Stefan Bedbur

In a metapopulation network, infectious diseases spread widely because of the travel of individuals. In the present study, we consider a modified metapopulation Susceptible-Infected-Removed (SIR) model with a latent period, which we call…

Physics and Society · Physics 2017-08-02 Kazue Kudo , Kanako Mizuno

We investigate final outcome properties of an SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than…

Probability · Mathematics 2024-04-08 Frank Ball , David Sirl , Pieter Trapman

Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…

Physics and Society · Physics 2014-07-23 Lara Goscé , David A W Barton , Anders Johansson

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

In this paper we consider a model for the spread of a stochastic SIR (Susceptible $\to$ Infectious $\to$ Recovered) epidemic on a network of individuals described by a random intersection graph. Individuals belong to a random number of…

Probability · Mathematics 2014-04-29 Frank G. Ball , David J. Sirl , Pieter Trapman

Ordinary differential equation (ODE) models used in mathematical epidemiology assume explicitly or implicitly large populations. For the study of infections in a hospital this is an extremely restrictive assumption as typically a hospital…

Populations and Evolution · Quantitative Biology 2023-08-21 Fabio A. C. C. Chalub , Antonio Gómez-Corral , Martín López-García , Fátima Palacios-Rodríguez

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

We study the Susceptible-Infected-Recovered model of epidemics in the vicinity of the threshold infectivity. We derive the distribution of total outbreak size in the limit of large population size $N$. This is accomplished by mapping the…

Populations and Evolution · Quantitative Biology 2009-11-13 David A. Kessler , Nadav M. Shnerb

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

Dynamical Systems · Mathematics 2021-04-27 William G. Faris

Background: The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…

Other Quantitative Biology · Quantitative Biology 2008-01-16 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alessandro Vespignani

The spread of an epidemic process is considered in the context of a spatial SIR stochastic model that includes a parameter $0\le p\le 1$ that assigns weights $p$ and $1- p$ to global and local infective contacts respectively. The model was…

Populations and Evolution · Quantitative Biology 2020-01-29 Gabriel Fabricius , Alberto Maltz

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

The disease spreading on complex networks is studied in SIR model. Simulations on empirical complex networks reveal two specific regimes of disease spreading: local containment and epidemic outbreak. The variables measuring the extent of…

Physics and Society · Physics 2013-04-02 Alen Lancic , Nino Antulov-Fantulin , Mile Sikic , Hrvoje Stefancic

The viral load is known to be a chief predictor of the risk of transmission of infectious diseases. In this work, we investigate the role of the individuals' viral load in the disease transmission by proposing a new…

Adaptation and Self-Organizing Systems · Physics 2023-03-29 Rossella Della Marca , Nadia Loy , Andrea Tosin

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

Epidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of…

Physics and Society · Physics 2020-09-08 Bnaya Gross , Shlomo Havlin

This paper is concerned with the analysis of vaccination strategies in a stochastic SIR (susceptible $\to$ infected $\to$ removed) model for the spread of an epidemic amongst a population of individuals with a random network of social…

Physics and Society · Physics 2016-11-16 Frank Ball , David Sirl

We study the SIR model of epidemics on positively correlated heterogeneous networks with population variability, and explore the dependence of the final outbreak size on the network heterogeneity strength and basic reproduction number $R_0$…

Statistical Mechanics · Physics 2023-06-16 Alexander Leibenzon , Michael Assaf