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Related papers: MedSafetyBench: Evaluating and Improving the Medic…

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Large language models (LLMs) have a transformative impact on a variety of scientific tasks across disciplines including biology, chemistry, medicine, and physics. However, ensuring the safety alignment of these models in scientific research…

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large language models (LLMs) demonstrate significant potential in advancing medical applications, yet their capabilities in addressing medical ethics challenges remain underexplored. This paper introduces MedEthicEval, a novel benchmark…

Computation and Language · Computer Science 2025-03-05 Haoan Jin , Jiacheng Shi , Hanhui Xu , Kenny Q. Zhu , Mengyue Wu

Ensuring the general efficacy and goodness for human beings from medical large language models (LLM) before real-world deployment is crucial. However, a widely accepted and accessible evaluation process for medical LLM, especially in the…

As large language models (LLMs) are increasingly deployed as agents, their integration into interactive environments and tool use introduce new safety challenges beyond those associated with the models themselves. However, the absence of…

Computation and Language · Computer Science 2025-05-21 Zhexin Zhang , Shiyao Cui , Yida Lu , Jingzhuo Zhou , Junxiao Yang , Hongning Wang , Minlie Huang

Large language models (LLMs) are increasingly applied in financial scenarios. However, they may produce harmful outputs, including facilitating illegal activities or unethical behavior, posing serious compliance risks. To systematically…

Computation and Language · Computer Science 2026-05-04 Yutao Hou , Yihan Jiang , Yuhan Xie , Jian Yang , Liwen Zhang , Hailiang Huang , Guanhua Chen , Yun Chen

In the rapidly evolving field of artificial intelligence, large language models (LLMs) have emerged as powerful tools for a myriad of applications, from natural language processing to decision-making support systems. However, as these…

Computation and Language · Computer Science 2025-07-08 Jianchao Ji , Yutong Chen , Mingyu Jin , Wujiang Xu , Wenyue Hua , Yongfeng Zhang

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

The code generation capabilities of large language models(LLMs) have emerged as a critical dimension in evaluating their overall performance. However, prior research has largely overlooked the security risks inherent in the generated code.…

Cryptography and Security · Computer Science 2025-06-23 Xinghang Li , Jingzhe Ding , Chao Peng , Bing Zhao , Xiang Gao , Hongwan Gao , Xinchen Gu

As large language models (LLMs) evolve from conversational assistants into autonomous agents, evaluating the safety of their actions becomes critical. Prior safety benchmarks have primarily focused on preventing generation of harmful…

Computation and Language · Computer Science 2026-03-04 Adi Simhi , Jonathan Herzig , Martin Tutek , Itay Itzhak , Idan Szpektor , Yonatan Belinkov

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

The application of large language models (LLMs) in healthcare holds significant promise for enhancing clinical decision-making, medical research, and patient care. However, their integration into real-world clinical settings raises critical…

Computers and Society · Computer Science 2025-09-18 Manar Aljohani , Jun Hou , Sindhura Kommu , Xuan Wang

Most safety testing efforts for large language models (LLMs) today focus on evaluating foundation models. However, there is a growing need to evaluate safety at the application level, as components such as system prompts, retrieval…

Software Engineering · Computer Science 2025-07-15 Jia Yi Goh , Shaun Khoo , Nyx Iskandar , Gabriel Chua , Leanne Tan , Jessica Foo

Inaccuracies in existing or generated clinical text may lead to serious adverse consequences, especially if it is a misdiagnosis or incorrect treatment suggestion. With Large Language Models (LLMs) increasingly being used across diverse…

Computation and Language · Computer Science 2026-02-06 Congbo Ma , Yichun Zhang , Yousef Al-Jazzazi , Ahamed Foisal , Laasya Sharma , Yousra Sadqi , Khaled Saleh , Jihad Mallat , Farah E. Shamout

While Medical Large Language Models (MedLLMs) have demonstrated remarkable potential in clinical tasks, their ethical safety remains insufficiently explored. This paper introduces $\textbf{MedEthicsQA}$, a comprehensive benchmark comprising…

Computation and Language · Computer Science 2025-07-01 Jianhui Wei , Zijie Meng , Zikai Xiao , Tianxiang Hu , Yang Feng , Zhijie Zhou , Jian Wu , Zuozhu Liu

Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-30 Kaixuan Wang , Chenxin Diao , Jason T. Jacques , Zhongliang Guo , Shuai Zhao