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Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Biological imaging data are often partially confounded or contain unwanted variability. Examples of such phenomena include variable lighting across microscopy image captures, stain intensity variation in histological slides, and batch…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Craig A. Glastonbury , Michael Ferlaino , Christoffer Nellåker , Cecilia M. Lindgren

We propose an attention-based method that aggregates local image features to a subject-level representation for predicting disease severity. In contrast to classical deep learning that requires a fixed dimensional input, our method operates…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Sumedha Singla , Mingming Gong , Siamak Ravanbakhsh , Frank Sciurba , Barnabas Poczos , Kayhan N. Batmanghelich

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

This paper studies the context aggregation problem in semantic image segmentation. The existing researches focus on improving the pixel representations by aggregating the contextual information within individual images. Though impressive,…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Zhenchao Jin , Tao Gong , Dongdong Yu , Qi Chu , Jian Wang , Changhu Wang , Jie Shao

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Soumick Chatterjee , Franziska Gaidzik , Alessandro Sciarra , Hendrik Mattern , Gábor Janiga , Oliver Speck , Andreas Nürnberger , Sahani Pathiraja

As black-box AI-driven decision-making systems become increasingly widespread in modern document processing workflows, improving their transparency and reliability has become critical, especially in high-stakes applications where biases or…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Saifullah Saifullah , Stefan Agne , Andreas Dengel , Sheraz Ahmed

Learning medical visual representations from image-report pairs through joint learning has garnered increasing research attention due to its potential to alleviate the data scarcity problem in the medical domain. The primary challenges stem…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jun Wang , Lixing Zhu , Xiaohan Yu , Abhir Bhalerao , Yulan He

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Trust in predictions made by machine learning models is increased if the model generalizes well on previously unseen samples and when inference is accompanied by cogent explanations of the reasoning behind predictions. In the image…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Edward Verenich , Alvaro Velasquez , Nazar Khan , Faraz Hussain

In biomedical research, to obtain more accurate prediction results from a target study, leveraging information from multiple similar source studies is proved to be useful. However, in many biomedical applications based on real-world data,…

Methodology · Statistics 2025-12-29 Xiaokang Liu , Jie Hu , Naimin Jing , Yang Ning , Cheng Yong Tang , Runze Li , Yong Chen

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

In biological research, fluorescence staining is a key technique to reveal the locations and morphology of subcellular structures. However, it is slow, expensive, and harmful to cells. In this paper, we model it as a deep learning task…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Donghao Zhou , Chunbin Gu , Junde Xu , Furui Liu , Qiong Wang , Guangyong Chen , Pheng-Ann Heng

Lesion detection is a fundamental problem in the computer-aided diagnosis scheme for mammography. The advance of deep learning techniques have made a remarkable progress for this task, provided that the training data are large and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Zheren Li , Zhiming Cui , Sheng Wang , Yuji Qi , Xi Ouyang , Qitian Chen , Yuezhi Yang , Zhong Xue , Dinggang Shen , Jie-Zhi Cheng

In applied image segmentation tasks, the ability to provide numerous and precise labels for training is paramount to the accuracy of the model at inference time. However, this overhead is often neglected, and recently proposed segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Kuai Yu , Hakeem Frank , Daniel Wilson

With the spread of COVID-19 over the world, the need arose for fast and precise automatic triage mechanisms to decelerate the spread of the disease by reducing human efforts e.g. for image-based diagnosis. Although the literature has shown…

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

Existing plant disease classification models have achieved remarkable performance in recognizing in-laboratory diseased images. However, their performance often significantly degrades in classifying in-the-wild images. Furthermore, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Tianqi Wei , Zhi Chen , Zi Huang , Xin Yu