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We present a causal inference framework to improve Weakly-Supervised Semantic Segmentation (WSSS). Specifically, we aim to generate better pixel-level pseudo-masks by using only image-level labels -- the most crucial step in WSSS. We…

Computer Vision and Pattern Recognition · Computer Science 2020-10-08 Dong Zhang , Hanwang Zhang , Jinhui Tang , Xiansheng Hua , Qianru Sun

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Medical image datasets can have large number of images representing patients with different health conditions and various disease severity. When dealing with raw unlabeled image datasets, the large number of samples often makes it hard for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Roozbeh Yousefzadeh

Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Muyi Sun , Guanhong Zhang

Segmentation in dense visual scenes poses significant challenges due to occlusions, background clutter, and scale variations. To address this, we introduce PerSense, an end-to-end, training-free, and model-agnostic one-shot framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Muhammad Ibraheem Siddiqui , Muhammad Umer Sheikh , Hassan Abid , Kevin Henry , Muhammad Haris Khan

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

Applications · Statistics 2024-03-07 Giacomo Lancia , Meri Varkila , Olaf Cremer , Cristian Spitoni

Medical images are often acquired in different settings, requiring harmonization to adapt to the operating point of algorithms. Specifically, to standardize the physical spacing of imaging voxels in heterogeneous inference settings, images…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Samuel Joutard , Maximilian Pietsch , Raphael Prevost

In decision-making systems, it is important to have classifiers that have calibrated uncertainties, with an optimisation objective that can be used for automated model selection and training. Gaussian processes (GPs) provide uncertainty…

Machine Learning · Statistics 2020-03-05 Vincent Dutordoir , Mark van der Wilk , Artem Artemev , James Hensman

Population-level disease prediction estimates the number of potential patients of particular diseases in some location at a future time based on (frequently updated) historical disease statistics. Existing approaches often assume the…

Social and Information Networks · Computer Science 2022-02-08 Junyi Gao , Cao Xiao , Lucas M. Glass , Jimeng Sun

Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

Computer Vision and Pattern Recognition · Computer Science 2018-03-07 Ruqayya Awan , Navid Alemi Koohbanani , Muhammad Shaban , Anna Lisowska , Nasir Rajpoot

We consider a classifier whose test set is exposed to various perturbations that are not present in the training set. These test samples still contain enough features to map them to the same class as their unperturbed counterpart. Current…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Yuchen Li , Safwan Hossain , Kiarash Jamali , Frank Rudzicz

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

Domain gaps arising from variations in imaging devices and population distributions pose significant challenges for machine learning in medical image analysis. Existing image-to-image translation methods primarily aim to learn mappings…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Tianyang Zhang , Xinxing Cheng , Jun Cheng , Shaoming Zheng , He Zhao , Huazhu Fu , Alejandro F Frangi , Jiang Liu , Jinming Duan

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

Saliency map detection, as a method for detecting important regions of an image, is used in many applications such as image classification and recognition. We propose that context detection could have an essential role in image saliency…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Mahdi Ahmadi , Mohsen Hajabdollahi , Nader Karimi , Shadrokh Samavi

Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tianyi Ren , Juampablo Heras Rivera , Hitender Oswal , Yutong Pan , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Unsupervised pathology detection trains models on non-pathological data to flag deviations as pathologies, offering strong generalizability for identifying novel diseases and avoiding costly annotations. However, building reliable normality…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Sinchee Chin , Yinuo Ma , Xiaochen Yang , Jing-Hao Xue , Wenming Yang

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge