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Multimodal Large Language Models (MLLMs) suffer from severe training inefficiency issue, which is associated with their massive model sizes and visual token numbers. Existing efforts in efficient training focus on reducing model sizes or…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Dingkun Zhang , Shuhan Qi , Yulin Wu , Xinyu Xiao , Xuan Wang , Long Chen

Pre-training large language models has become a standard in the natural language processing community. Such models are pre-trained on generic data (e.g. BookCorpus and English Wikipedia) and often fine-tuned on tasks in the same domain.…

Computation and Language · Computer Science 2020-10-05 Kristjan Arumae , Qing Sun , Parminder Bhatia

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Clinical Question-Answering (CQA) industry systems are increasingly rely on Large Language Models (LLMs), yet their deployment is often guided by the assumption that domain-specific fine-tuning is essential. Although specialised medical…

Computation and Language · Computer Science 2026-01-21 Sushant Kumar Ray , Gautam Siddharth Kashyap , Sahil Tripathi , Nipun Joshi , Vijay Govindarajan , Rafiq Ali , Jiechao Gao , Usman Naseem

Dense large language models(LLMs) face critical efficiency bottlenecks as they rigidly activate all parameters regardless of input complexity. While existing sparsity methods(static pruning or dynamic activation) address this partially,…

Computation and Language · Computer Science 2025-02-27 Yiheng Yang , Yujie Wang , Chi Ma , Lei Yu , Emmanuele Chersoni , Chu-Ren Huang

Sparsity-aware training is an effective approach for transforming large language models (LLMs) into hardware-friendly sparse patterns, thereby reducing latency and memory consumption during inference. In this paper, we propose Continuous…

Machine Learning · Computer Science 2025-10-01 Weiyu Huang , Yuezhou Hu , Jun Zhu , Jianfei Chen

Recent studies have shown that Machine Learning (ML) models can exhibit bias in real-world scenarios, posing significant challenges in ethically sensitive domains such as healthcare. Such bias can negatively affect model fairness, model…

Machine Learning · Computer Science 2025-09-05 Junyu Yan , Feng Chen , Yuyang Xue , Yuning Du , Konstantinos Vilouras , Sotirios A. Tsaftaris , Steven McDonagh

This paper introduces an approach that combines the language reasoning capabilities of large language models (LLMs) with the benefits of local training to tackle complex, domain-specific tasks. Specifically, the authors demonstrate their…

Computation and Language · Computer Science 2023-08-04 V. K. Cody Bumgardner , Aaron Mullen , Sam Armstrong , Caylin Hickey , Jeff Talbert

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

Large language models (LLMs) have demonstrated increasingly sophisticated performance in medical and other fields of knowledge. Traditional methods of creating specialist LLMs require extensive fine-tuning and training of models on large…

Computation and Language · Computer Science 2025-02-25 Sean Wu , Michael Koo , Fabien Scalzo , Ira Kurtz

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Deploying Large Language Models (LLMs) on edge devices remains challenging due to their quadratically increasing computations with the sequence length. Existing studies for dynamic attention pruning are designed for hardware with massively…

Artificial Intelligence · Computer Science 2025-07-29 Jiawen Qi , Chang Gao , Zhaochun Ren , Qinyu Chen

Biomedical literature often uses complex language and inaccessible professional terminologies. That is why simplification plays an important role in improving public health literacy. Applying Natural Language Processing (NLP) models to…

Computation and Language · Computer Science 2024-03-19 Zihao Li , Samuel Belkadi , Nicolo Micheletti , Lifeng Han , Matthew Shardlow , Goran Nenadic

Chat models are capable of answering a wide range of questions, however, the accuracy of their responses is highly uncertain. In this research, we propose a specialized PEFT-MedAware model where we utilize parameter-efficient fine-tuning…

Computation and Language · Computer Science 2023-11-20 Keivalya Pandya

Fine-tuning LLMs is both computationally and memory-intensive. While parameter-efficient fine-tuning methods, such as QLoRA and DoRA, reduce the number of trainable parameters and lower memory usage, they do not decrease computational cost.…

Unsupervised multitask pre-training has been the critical method behind the recent success of language models (LMs). However, supervised multitask learning still holds significant promise, as scaling it in the post-training stage trends…

Computation and Language · Computer Science 2024-12-02 Daixuan Cheng , Yuxian Gu , Shaohan Huang , Junyu Bi , Minlie Huang , Furu Wei

The performance on deep learning is significantly affected by volume of training data. Models pre-trained from massive dataset such as ImageNet become a powerful weapon for speeding up training convergence and improving accuracy. Similarly,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-18 Sihong Chen , Kai Ma , Yefeng Zheng

Vision-language foundation models (VLMs) show promise for diverse imaging tasks but often underperform on medical benchmarks. Prior efforts to improve performance include model finetuning, which requires large domain-specific datasets and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Arnav Singhvi , Vasiliki Bikia , Asad Aali , Akshay Chaudhari , Roxana Daneshjou

Large Transformer-based language models are pre-trained on corpora of varying sizes, for a different number of steps and with different batch sizes. At the same time, more fundamental components, such as the pre-training objective or…

Computation and Language · Computer Science 2021-05-12 M. Aßenmacher , P. Schulze , C. Heumann