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We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

Probability · Mathematics 2012-06-20 Sylvie Méléard , Viet Chi Tran

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

A fundamental problem in the study of phylogenetic networks is to determine whether or not a given phylogenetic network contains a given phylogenetic tree. We develop a quadratic-time algorithm for this problem for binary nearly-stable…

Data Structures and Algorithms · Computer Science 2022-08-29 Philippe Gambette , Andreas D. M. Gunawan , Anthony Labarre , Stéphane Vialette , Louxin Zhang

Phylogenetic networks extend phylogenetic trees to model non-vertical inheritance, by which a lineage inherits material from multiple parents. The computational complexity of estimating phylogenetic networks from genome-wide data with…

Populations and Evolution · Quantitative Biology 2022-06-28 Jingcheng Xu , Cécile Ané

The evolutionary processes of complex systems contain critical information regarding their functional characteristics. The generation time of edges provides insights into the historical evolution of various networked complex systems, such…

Artificial Intelligence · Computer Science 2025-01-14 En Xu , Can Rong , Jingtao Ding , Yong Li

We propose a reinforcement-learning algorithm to tackle the challenge of reconstructing phylogenetic trees. The search for the tree that best describes the data is algorithmically challenging, thus all current algorithms for phylogeny…

Populations and Evolution · Quantitative Biology 2023-03-14 Dana Azouri , Oz Granit , Michael Alburquerque , Yishay Mansour , Tal Pupko , Itay Mayrose

We present TreeClone, a latent feature allocation model to reconstruct tumor subclones subject to phylogenetic evolution that mimics tumor evolution. Similar to most current methods, we consider data from next-generation sequencing of tumor…

Applications · Statistics 2017-10-26 Tianjian Zhou , Subhajit Sengupta , Peter Mueller , Yuan Ji

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of evolutionary events acting at the population level, like recombination between genes, hybridization between lineages, and lateral gene…

Populations and Evolution · Quantitative Biology 2007-11-26 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

Probability · Mathematics 2012-11-30 Elchanan Mossel , Sebastien Roch

The reconstruction of phylogenetic trees based on viral genetic sequence data sequentially sampled from an epidemic provides estimates of the past transmission dynamics, by fitting epidemiological models to these trees. To our knowledge,…

Populations and Evolution · Quantitative Biology 2013-06-17 Amaury Lambert , Helen K. Alexander , Tanja Stadler

Phylogenetic trees describe the evolutionary history of a group of present-day species from a common ancestor. These trees are typically reconstructed from aligned DNA sequence data. In this paper we analytically address the following…

Populations and Evolution · Quantitative Biology 2008-07-14 Mike Steel , Laszlo Szekely , Elchanan Mossel

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

Populations and Evolution · Quantitative Biology 2016-10-03 Laura Jetten , Leo van Iersel

The adoption of the distributed paradigm has allowed applications to increase their scalability, robustness and fault tolerance, but it has also complicated their structure, leading to an exponential growth of the applications'…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-05-23 Ioannis Giannakopoulos , Dimitrios Tsoumakos , Nectarios Koziris

Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…

Data Structures and Algorithms · Computer Science 2008-12-10 Radu Mihaescu , Cameron Hill , Satish Rao

We introduce a new phylogenetic reconstruction algorithm which, unlike most previous rigorous inference techniques, does not rely on assumptions regarding the branch lengths or the depth of the tree. The algorithm returns a forest which is…

Populations and Evolution · Quantitative Biology 2011-09-30 Constantinos Daskalakis , Elchanan Mossel , Sebastien Roch

Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train…

Machine Learning · Computer Science 2023-02-22 Alberto Archetti , Eugenio Lomurno , Francesco Lattari , André Martin , Matteo Matteucci

We demonstrate the use of computational phylogenetic techniques to solve a central problem in inferential network monitoring. More precisely, we design a novel algorithm for multicast-based delay inference, i.e. the problem of…

Probability · Mathematics 2011-09-07 Shankar Bhamidi , Ram Rajagopal , Sebastien Roch

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

The automatic generation of computer programs is one of the main applications with practical relevance in the field of evolutionary computation. With program synthesis techniques not only software developers could be supported in their…

Neural and Evolutionary Computing · Computer Science 2021-08-30 Dominik Sobania , Dirk Schweim , Franz Rothlauf

Designing flexible probabilistic models over tree topologies is important for developing efficient phylogenetic inference methods. To do that, previous works often leverage the similarity of tree topologies via hand-engineered heuristic…

Populations and Evolution · Quantitative Biology 2023-10-17 Tianyu Xie , Cheng Zhang
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