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Related papers: Med-Real2Sim: Non-Invasive Medical Digital Twins u…

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A digital health twin can be defined as a virtual model of a physical person, in this specific case, a patient. This virtual model is constituted by multidimensional data that can host from clinical, molecular and therapeutic parameters to…

Computers and Society · Computer Science 2022-12-02 Manuel Cossio

Digital twins are virtual systems designed to predict how a real-world process will evolve in response to interventions. This modelling paradigm holds substantial promise in many applications, but rigorous procedures for assessing their…

Methodology · Statistics 2023-11-03 Rob Cornish , Muhammad Faaiz Taufiq , Arnaud Doucet , Chris Holmes

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

A digital twin is a computer model that represents an individual, for example, a component, a patient or a process. In many situations, we want to gain knowledge about an individual from its data while incorporating imperfect physical…

Machine Learning · Statistics 2023-05-03 Michail Spitieris , Ingelin Steinsland

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Purpose: Digital twins are virtual interactive models of the real world, exhibiting identical behavior and properties. In surgical applications, computational analysis from digital twins can be used, for example, to enhance situational…

A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

Cardiac digital twins are computational tools capturing key functional and anatomical characteristics of patient hearts for investigating disease phenotypes and predicting responses to therapy. When paired with large-scale computational…

Computational Engineering, Finance, and Science · Computer Science 2024-01-19 Julia Camps , Zhinuo Jenny Wang , Ruben Doste , Maxx Holmes , Brodie Lawson , Jakub Tomek , Kevin Burrage , Alfonso Bueno-Orovio , Blanca Rodriguez

Background and Objective: Precise preoperative planning and effective physician training for coronary interventions are increasingly important. Despite advances in medical imaging technologies, transforming static or limited dynamic imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

Digital Twins technology is revolutionizing decision-making in scientific research by integrating models and simulations with real-time data. Unlike traditional Structural Health Monitoring methods, which rely on computationally intensive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Mehrdad Shafiei Dizaji

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

This work is interested in digital twins, and the development of a simplified framework for them, in the context of dynamical systems. Digital twin is an ingenious concept that helps on organizing different areas of expertise aiming at…

Signal Processing · Electrical Eng. & Systems 2021-01-29 TG Ritto , FA Rochinha

Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…

Machine Learning · Computer Science 2023-07-12 Logan Nye

Digital twins are transforming engineering and applied sciences by enabling real-time monitoring, simulation, and predictive analysis of physical systems and processes. However, conventional digital twins rely primarily on passive data…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Matteo Torzoni , Domenico Maisto , Andrea Manzoni , Francesco Donnarumma , Giovanni Pezzulo , Alberto Corigliano

Insufficient data volume and quality are particularly pressing challenges in the adoption of modern subsymbolic AI. To alleviate these challenges, AI simulation uses virtual training environments in which AI agents can be safely and…

Artificial Intelligence · Computer Science 2025-09-01 Xiaoran Liu , Istvan David

Digital twins for cardiac electrophysiology are an enabling technology for precision cardiology. Current forward models are advanced enough to simulate the cardiac electric activity under different pathophysiological conditions and…

Optimization and Control · Mathematics 2025-05-05 Thomas Grandits , Karli Gillette , Gernot Plank , Simone Pezzuto

Digital twins are virtual replicas of physical entities and are poised to transform personalized medicine through the real-time simulation and prediction of human physiology. Translating this paradigm from engineering to biomedicine…

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge. Traditional physics-based modeling approaches are…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Xiajun Jiang , Sumeet Vadhavkar , Yubo Ye , Maryam Toloubidokhti , Ryan Missel , Linwei Wang

This paper explores the development and practical application of a predictive digital twin specifically designed for condition monitoring, using advanced mathematical models and thermal imaging techniques. Our work presents a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Daniel Menges , Florian Stadtmann , Henrik Jordheim , Adil Rasheed
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