Related papers: Med-Real2Sim: Non-Invasive Medical Digital Twins u…
Single-arm trials are an important study design for evaluating drug efficacy and safety without enrolling patients into a control arm. Although they do not provide the gold-standard evidence of randomized controlled trials, they are…
Digital twins are sophisticated software systems for the representation, monitoring, and control of cyber-physical systems, including automotive, avionics, smart manufacturing, and many more. Existing definitions and reference models of…
Systems for transport and processing of granular media are challenging to analyse, operate and optimise. In the mining and mineral processing industries these systems are chains of processes with complex interplay between the equipment,…
We introduce a novel digital twin framework for predictive maintenance of long-term physical systems. Using monitoring tire health as an application, we show how the digital twin framework can be used to enhance automotive safety and…
Patient-specific cardiac computational models are essential for the efficient realization of precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can provide non-invasive characterizations of cardiac…
Central to the digital transformation of the process industry are Digital Twins (DTs), virtual replicas of physical manufacturing systems that combine sensor data with sophisticated data-based or physics-based models, or a combination…
Simulating glucose dynamics in individuals with type 1 diabetes (T1D) is critical for developing personalized treatments and supporting data-driven clinical decisions. Existing models often miss key physiological aspects and are difficult…
With rapid digitization and digitalization, drawing a fine line between the digital and the physical world has become nearly impossible. It has become essential more than ever to integrate all spheres of life into a single Digital Thread to…
Recently there has been a surge of interest in developing Digital Twins of process flows in healthcare to better understand bottlenecks and areas of improvement. A key challenge is in the validation process. We describe a work in progress…
The dynamic nature of human health and comfort calls for adaptive systems that respond to individual physiological needs in real time. This paper presents an AI-enhanced digital twin framework that integrates biometric signals, specifically…
A cardiac digital twin is a virtual replica of a patient-specific heart, mimicking its anatomy and physiology. A crucial step of building a cardiac digital twin is anatomical twinning, where the computational mesh of the digital twin is…
We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…
Digital Twin, as an emerging technology related to Cyber-Physical Systems (CPS) and Internet of Things (IoT), has attracted increasing attentions during the past decade. Conceptually, a Digital Twin is a digital replica of a physical entity…
A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…
Digital twins are becoming powerful tools in industrial applications, offering virtual representations of cyber-physical systems. However, verification of these models remains a significant challenge due to the potentially large datasets…
Digital twins are virtual representations of physical objects or systems used for the purpose of analysis, most often via computer simulations, in many engineering and scientific disciplines. Recently, this approach has been introduced to…
Pedestrian dynamics simulates the fine-scaled trajectories of individuals in a crowd. It has been used to suggest public health interventions to reduce infection risk in important components of air travel, such as during boarding and in…
Smart Digital twins (SDTs) are being increasingly used to virtually replicate and predict the behaviors of complex physical systems through continual data assimilation enabling the optimization of the performance of these systems by…
In this study, we investigate the potential of fast-to-evaluate surrogate modeling techniques for developing a hybrid digital twin of a steel-reinforced concrete beam, serving as a representative example of a civil engineering structure. As…
Training effective artificial intelligence models for telecommunications is challenging due to the scarcity of deployment-specific data. Real data collection is expensive, and available datasets often fail to capture the unique operational…