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In this paper we show how to use one or more assembled or partially assembled genome as the basis for a compressed full-text index of its readset. Specifically, we build a labelled tree by taking the assembled genome as a trunk and grafting…

Data Structures and Algorithms · Computer Science 2021-06-02 Travis Gagie , Garance Gourdel , Giovanni Manzini

The run-length compressed Burrows-Wheeler transform (RLBWT) used in conjunction with the backward search introduced in the FM index is the centerpiece of most compressed indexes working on highly-repetitive data sets like biological…

Data Structures and Algorithms · Computer Science 2021-10-05 Jin Jie Deng , Wing-Kai Hon , Dominik Köppl , Kunihiko Sadakane

Variation graphs, which represent genetic variation within a population, are replacing sequences as reference genomes. Path indexes are one of the most important tools for working with variation graphs. They generalize text indexes to…

Data Structures and Algorithms · Computer Science 2017-01-13 Jouni Sirén

The Extended Burrows Wheeler transform (EBWT) helps to find the distance between two sequences. Implementation of an existing algorithm takes considerable amount of time for small size sequences. In this paper, we give a parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-02-02 Shashank Srikant

There are currently plenty of programs available for mapping short sequences (reads) to a genome. Most of them, however, including such popular and actively developed programs as Bowtie, BWA, TopHat and many others, are based on…

Genomics · Quantitative Biology 2019-08-06 Igor Seledtsov , Jaroslav Efremov , Vladimir Molodtsov , Victor Solovyev

We propose a novel transformer-based styled handwritten text image generation approach, HWT, that strives to learn both style-content entanglement as well as global and local writing style patterns. The proposed HWT captures the long and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Ankan Kumar Bhunia , Salman Khan , Hisham Cholakkal , Rao Muhammad Anwer , Fahad Shahbaz Khan , Mubarak Shah

Cartesian tree matching is a form of generalized pattern matching where a substring of the text matches with the pattern if they share the same Cartesian tree. This form of matching finds application for time series of stock prices and can…

Data Structures and Algorithms · Computer Science 2024-11-20 Eric M. Osterkamp , Dominik Köppl

When building Burrows-Wheeler Transforms (BWTs) of truly huge datasets, prefix-free parsing (PFP) can use an unreasonable amount of memory. In this paper we show how if a dataset can be broken down into small datasets that are not very…

Data Structures and Algorithms · Computer Science 2025-06-09 Diego Diaz-Dominguez , Travis Gagie , Veronica Guerrini , Ben Langmead , Zsuzsanna Liptak , Giovanni Manzini , Francesco Masillo , Vikram Shivakumar

With the rapid growing of data and number of applications, there is a crucial need of dictionary based reversible transformation techniques to increase the efficiency of the compression algorithms and hence contribute towards the…

Information Theory · Computer Science 2014-03-20 R. R. Baruah , V. Deka , M. P. Bhuyan

The Positional Burrows-Wheeler Transform (PBWT) is a fundamental data structure for the efficient representation and analysis of large-scale haplotype panels. For a panel of $h$ sequences $\{S_1, \dots, S_h\}$ over $m$ sites, a key…

Data Structures and Algorithms · Computer Science 2026-05-07 Paola Bonizzoni , Travis Gagie , Younan Gao

A bit catastrophe, loosely defined, is when a change in just one character of a string causes a significant change in the size of the compressed string. We study this phenomenon for the Burrows-Wheeler Transform (BWT), a string transform at…

Data Structures and Algorithms · Computer Science 2025-06-10 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Giuseppe Romana , Marinella Sciortino , Cristian Urbina

Ordering the collection of states of a given automaton starting from an order of the underlying alphabet is a natural move towards a computational treatment of the language accepted by the automaton. Along this path, Wheeler \emph{graphs}…

Formal Languages and Automata Theory · Computer Science 2021-06-14 Giovanna D'Agostino , Davide Martincigh , Alberto Policriti

We show how to build several data structures of central importance to string processing, taking as input the Burrows-Wheeler transform (BWT) and using small extra working space. Let $n$ be the text length and $\sigma$ be the alphabet size.…

Data Structures and Algorithms · Computer Science 2019-08-14 Nicola Prezza , Giovanna Rosone

Some recent results have introduced external-memory algorithms to compute self-indexes of a set of strings, mainly via computing the Burrows-Wheeler Transform (BWT) of the input strings. The motivations for those results stem from…

Data Structures and Algorithms · Computer Science 2015-06-12 Paola Bonizzoni , Gianluca Della Vedova , Yuri Pirola , Marco Previtali , Raffaella Rizzi

The notion of Wheeler languages is rooted in the Burrows-Wheeler transform (BWT), one of the most central concepts in data compression and indexing. The BWT has been generalized to finite automata, the so-called Wheeler automata, by Gagie…

Formal Languages and Automata Theory · Computer Science 2025-04-29 Ruben Becker , Giuseppa Castiglione , Giovanna D'Agostino , Alberto Policriti , Nicola Prezza , Antonio Restivo , Brian Riccardi

We show how to merge two run-length compressed Burrows-Wheeler Transforms (RLBWTs) into a run-length compressed extended Burrows-Wheeler Transform (eBWT) in $O (r)$ space and $O ((r + L) \log (m + n))$ time, where $m$ and $n$ are the…

Data Structures and Algorithms · Computer Science 2026-04-16 Travis Gagie

The Burrows Wheeler transform has applications in data compression as well as full text indexing. Despite its important applications and various existing algorithmic approaches the construction of the transform for large data sets is still…

Data Structures and Algorithms · Computer Science 2016-04-25 German Tischler

Vision Transformers (ViTs) and Swin Transformers (Swin) are currently state-of-the-art in computational pathology. However, domain experts are still reluctant to use these models due to their lack of interpretability. This is not…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Manuel Tran , Amal Lahiani , Yashin Dicente Cid , Melanie Boxberg , Peter Lienemann , Christian Matek , Sophia J. Wagner , Fabian J. Theis , Eldad Klaiman , Tingying Peng

We investigate various connections between the clustering for the Burrows-Wheeler transform, a lossless algorithm used in data compression, and languages of interval exchange transformations. We show that a primitive word $u$ clusters for a…

Combinatorics · Mathematics 2026-03-18 Sébastien Ferenczi , Luca Q. Zamboni

Prior work inspired by compression algorithms has described how the Burrows Wheeler Transform can be used to create a distance measure for bioinformatics problems. We describe issues with this approach that were not widely known, and…

Cryptography and Security · Computer Science 2020-02-19 Edward Raff , Charles Nicholas , Mark McLean