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While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

The advent of large language models (LLMs) has unlocked great opportunities in complex data management tasks, particularly in question answering (QA) over complicated multi-table relational data. Despite significant progress, systematically…

Artificial Intelligence · Computer Science 2024-12-02 Zipeng Qiu , You Peng , Guangxin He , Binhang Yuan , Chen Wang

During the patient's hospitalization, the physician must record daily observations of the patient and summarize them into a brief document called "discharge summary" when the patient is discharged. Automated generation of discharge summary…

Computation and Language · Computer Science 2023-03-13 Kenichiro Ando , Mamoru Komachi , Takashi Okumura , Hiromasa Horiguchi , Yuji Matsumoto

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language models (LLMs) are increasingly evident for accurate question answering across various domains. However, rigorous evaluation of their performance on complex question-answering (QA) capabilities is essential before deployment…

Computation and Language · Computer Science 2025-09-03 Reem Abdel-Salam , Mary Adewunmi , Modinat A. Abayomi

The growing volume of academic papers has made it increasingly difficult for researchers to efficiently extract key information. While large language models (LLMs) based agents are capable of automating question answering (QA) workflows for…

Computation and Language · Computer Science 2026-03-31 Tiancheng Huang , Ruisheng Cao , Yuxin Zhang , Zhangyi Kang , Zijian Wang , Chenrun Wang , Yijie Luo , Hang Zheng , Lirong Qian , Lu Chen , Kai Yu

Recent advances in Large Language Models (LLMs) have enabled the development of text-to-SQL models that allow clinicians to query structured data stored in Electronic Health Records (EHRs) using natural language. However, deploying these…

Computation and Language · Computer Science 2025-12-23 Gyubok Lee , Woosog Chay , Edward Choi

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

To facilitate healthcare delivery, language models (LMs) have significant potential for clinical prediction tasks using electronic health records (EHRs). However, in these high-stakes applications, unreliable decisions can result in high…

Computation and Language · Computer Science 2024-11-07 Zizhang Chen , Peizhao Li , Xiaomeng Dong , Pengyu Hong

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Large Language Models (LLMs) perform well on standard reasoning and question-answering benchmarks, yet such evaluations often fail to capture their ability to handle long-tail, expertise-intensive knowledge in real-world professional…

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

The discharge summary is a one of critical documents in the patient journey, encompassing all events experienced during hospitalization, including multiple visits, medications, tests, surgery/procedures, and admissions/discharge. Providing…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Imjin Ahn , Hansle Gwon , Young-Hak Kim , Tae Joon Jun , Sanghyun Park

OpenNotes enables patients to access EHR notes, but medical jargon can hinder comprehension. To improve understanding, we evaluated closed- and open-source LLMs for extracting and prioritizing key medical terms using prompting, fine-tuning,…

Computation and Language · Computer Science 2026-05-08 Won Seok Jang , Sharmin Sultana , Zonghai Yao , Hieu Tran , Zhichao Yang , Sunjae Kwon , Hong Yu

By summarizing longer consumer health questions into shorter and essential ones, medical question-answering systems can more accurately understand consumer intentions and retrieve suitable answers. However, medical question summarization is…

Computation and Language · Computer Science 2025-10-01 Wenpeng Lu , Sibo Wei , Xueping Peng , Yi-fei Wang , Usman Naseem , Shoujin Wang

In this paper, we introduce S-MedQA, an English medical question-answering (QA) dataset designed for benchmarking large language models (LLMs) in fine-grained clinical specialties. S-MedQA consists of over 24k examples, covering 15 medical…

Computation and Language · Computer Science 2026-01-28 Xinlan Yan , Di Wu , Yibin Lei , Christof Monz , Iacer Calixto

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Artificial Intelligence · Computer Science 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Electronic medical records (EMRs) contain essential data for patient care and clinical research. With the diversity of structured and unstructured data in EHR, data visualization is an invaluable tool for managing and explaining these…

Databases · Computer Science 2025-06-17 Haodi Zhang , Siqi Ning , Qiyong Zheng , Jinyin Nie , Liangjie Zhang , Weicheng Wang , Yuanfeng Song